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Division of Infectious Diseases Clinical Fellows

Eran Bendavid

Alicia Chang

Aarthi Chary

Birgitt Dau

Shirit Einav

Philip Grant

Anita Koshy

Philip Pang

Cybèle Renault

Frank Trinh

Stephanie Barrett Troy

 

Eran Bendavid

Eran Bendavid, completing his 2 nd year as a Clinical Fellow, is a native of Israel. He received his MD degree from Harvard Medical School, and completed his residency at the University of Pennsylvania and at Stanford.

His research interests include: Utilizing methods from several disciplines -- political science, economics and epidemiology -- to study the prevention and treatment of infectious diseases in developing countries. His current projects are focused on modeling cost effectiveness of increasing the use of CD4 counts in resource poor setting; the relationship of governance to health care delivery; the behavioral effects of increased HAART availability; and the design of affordable genotyping techniques for resource-poor regions.

Among his mentors are Drs. Doug Owens, Dennis Israelski, David Katzenstein, and Bob Shafer.

List of publications:

1. Weissman JS, Rothschild J, Bendavid E, Cook, EF, Sprivulis P, David-Kasdan J, Bender M, Evans S, Haug P, Lloyd J, Selbovitz LG, Murff H, Bates DW. Hospital Workload and Adverse Events. Accepted, Medical Care.

2. Bendavid E, Kaganova J, Needleman J, Gruenberg L, Weissman JS. Complication Rates on Weekends and Weekdays in U.S. Hospitals. Accepted, American Journal of Medicine.

3. Campbell EG, Vogeli C, Yucel R, Bendavid E, Jones LM, Anderson LA, Louis KS. Data Withholding and the Next Generation Scientists: Results of a National Survey. Academic Medicine. 81(2): 128-136, 2006.

4. Weissman, JS, Bendavid E. Should U.S. Hospitals Go 24/7? American Journal of Medicine. 117(3): 202-203, 2004.

5. Campbell EG, Bendavid E. Data-sharing and data-withholding in genetics and the life sciences: results of a national survey of technology transfer officers. Journal of Health Care Law & Policy. 6(2):241-55, 2003.

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Alicia Chang

Alicia Chang received her MD degree from UCSF, and completed her residency in Internal Medicine at Brigham and Women’s Hospital in Boston. Currently in her 4 th year at Stanford, she is completing the MS degree in Epidemiology under the mentorship of Dr. Julie Parsonnet. Dr. Chang’s research interests include understanding the effects of chronic disease on host susceptibility to infections, principally to M. tuberculosis. Her current projects include a clinical study to evaluate the effect of diabetes on risk of active TB, a collaboration with the Santa Clara County TB clinic to study the effect of lengthening isoniazid therapy for latent TB infection, and a clinical challenge study to evaluate the effect of H. pylori and hypochlorhydria on subsequent infection with enteropathogenic E. coli.

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Aarthi Chary

Aarthi Chary, MD is a 1st year fellow originally from Ohio, where she  completed medical school at Case Western Reserve University. More recently she has called Oregon home, after completing her internal medicine training at Oregon Health Sciences University and spending an interim year working as both a teaching hospitalist and a research assistant in a tuberculosis lab. Her research interests are focused primarily on clinical HIV, public health and epidemiology.

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Birgitt Dau

Birgitt L. Dau, MD, is a 2nd year ID fellow.  She completed her medical
school training at the University of Chicago Pritzker School of Medicine.
Her residency training was at the University of Washington in Seattle.  Her
research is focused on looking at mutational patterns in HIV and how they
are associated with clinical outcomes for HIV-infected patients.  Currently
she is analysing the connection domain of HIV reverse transciptase in a
population of highly treatment-experienced patients.  She is looking at what
antiretroviral treatment history is associated with developing these
mutations, and what impact these mutations have on response to future
antiretroviral therapy.

Mentor: Mark Holodniy, MD

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Shirit Enav

Shirit Einav, MD, 3rd year ID fellow. She completed her medical school training at the Sackler school of medicine in Tel-Aviv university, Israel. She did her residency in Internal Medicine at Beth Israel Deaconess Medical Center, Harvard University, Boston. Her research interest is molecular virology of Hepatitis C virus. More specifically, she is interested in identifying new viral targets for potential novel anti-HCV specific treatment. She is also interested in viral-host interactions and in viral-induced oncogenesis.

Mentor: Dr. Jeffrey Glenn (GI)

Included among her ongoing projects: translating her recently identified target of NS4B GTpase domain to the development of a novel anti-HCV strategy, identifying new viral-host protein-protein interactions by a novel methodology, identifying novel mechanisms for viral related hepatocarcinogenesis and more.

List of publications:

• Chou S, Einav S, and Shafer RW (2007). Mechanisms of resistance to antiviral agents. In Manual of clinical microbiology, 9th edition, Murray PR ed, Baron EJ ed, Jorgensen JH ed, Pfaller MA ed, Tenover FC ed, and Yolken RH ed. Americal Society of Microbiology, In press.

• Einav S, Elazar M, Danieli T, and Glenn JS. A nucleotide binding motif in HCV NS4B mediates HCV RNA replication. Journal of virology. 2004 Oct 78 (20):11288-95.

• Einav S, Glenn JS. Prenylation inhibitors: a novel class of antiviral agents. J antimicrob chemo. 2003 November; 52: 883-886. Review.

• Einav S, Koziel MJ. Immunopathogenesis of Hepatitis C in the Immunosuppressed host. Transpl Infect Dis. 2002 June; 4(2):85-92. Review.

• Einav S, Pozdnyakova OO, Ma M, Carroll MC. Complement C4 is protective for lupus disease independent of C3. Journal of Immunology. 2002 Feb1;168(3):1036-41.

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Philip Grant

Phil Grant, MD, is a 1st year fellow originally from Pasadena, California. He completed his medical school at UCSF and residency at University of Washington. His research interests are focused on clinical HIV.

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Anita Koshy

Anita Koshy, MD (2 nd year) originally hails from the great state of New Mexico. She attended medical school at Duke University, where she was voted least likely to ever recross the Mason-Dixon Line. She began her training in Internal Medicine at University of Washington in Seattle, WA. After a scant two years, she decided Internal Medicine residency was too short and changed to Neurology residency at the University of California, San Francisco. After completing her Neurology residency, she decided to further extend her housestaff years by becoming an Infectious Disease fellow, with the goal of ultimately settling in the small but burgeoning field of neuro-infectious disease. Her research interests are in the immunology and pathogenesis of central nervous system infections. To that end, she will be working with John Boothroyd, PhD who studies Toxoplasmosis gondiiin vitro as well as in a murine model. Her specific fellowship projects have not been defined at this time, as she is currently on maternity leave.

Mentor: John Boothroyd, PhD

Publications:

Chiu, CY, Rouskin S, Koshy A, Urisman A, Fischer K, Yagi S, Schnurr D, Eckburg PB, Tompkins LS, Blackburn BG, Ganem D, DeRisi JC. Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult. CID 2006; 43 (8): e71-e76.

Jiang X, Mu D, Manabal C, Koshy AA, Christen S, Tauber MG, Vexler ZS, Ferriero D. Differential vulnerability of immature murine neurons to oxygen-glucose deprivation. Exp Neurology 2004; 190(1): 224-32.

Almli LA, Hamrick SE, Koshy AA, Tauber MG, Ferriero DM. Multiple pathways of neuroprotection against oxidative stress and excitotoxic injury in the immature primary hippocampal neurons. Dev Brain Research 2001; 132: 121-129.

Koshy AA, Almli LM, Tauber M, Ferriero DM. Immature hippocampal neurons in vitro show increased susceptibility to reactive oxygen species. Society for Neurosci Abst 1998; 24:805.

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Philip Pang

Phillip S. Pang, M.D., Ph.D., went to Stanford University for his undergraduate degree in biological sciences.  He completed the MST program at Columbia University in 2004, and returned to Stanford for his residency in Internal Medicine.  He is currently fast tracking in the Infectious Disease Fellowship here at Stanford.  His Ph.D. thesis primarily focused on RNA protein interactions, specifically the NS3 helicase from hepatitis C and it's molecular properties.  A second part of his Ph.D. work focused on designing new statistical techniques to analyze related genomes in an effort to extract functional information: in silico molecular analysis. International and domestic patents on the SHEVEK method which resulted from his work are currently pending.  His current interests are exploring through both wet lab and dry lab techniques the immunology and pathogenesis of viruses.

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Cybèle Renault

Cybèle Renault, M.D., D.T.M.H. (3rd year) is originally from Bethesda, Maryland. She completed her medical school training at The University of Chicago, Pritzker School of Medicine and continued at The University of Chicago for her residency in Internal Medicine, followed by a Chief Resident year at John H. Stroger, Jr. Hospital of Cook
County. She received her Diploma in Tropical Medicine and Hygiene (D.T.M.H.) from the Gorgas Memorial Institute in Lima, Peru in March 2007. Her research interests include evaluating the use of low-cost diagnostic tests in developing countries, studying the clinical use of diagnostic tests for sexually transmitted infections at both urogenital and extragenital sites, and examining the relationship between sexually transmitted infections and HIV infectivity. Her specific fellowship projects include: a validation study of a new technology for CD4+ T lymphocyte enumeration in rural Burkina Faso, a test-of-cure study for chlamydial cervicitis, and an evaluation of the impact of genital and non-genital gonococcal and chlamydial infections on plasma HIV viral load in HIV-infected patients.

Mentor: Dennis M. Israelski, MD

Publications:

Renault CA, Eckburg PB. Internal Medicine: Handbook for Clinicians
(Resident Survival Guide), Infectious Diseases chapter (Accepted;
Publication pending, 2007).

Renault CA, Hall C, Kent CK, Klausner JD. Use of NAATs for STD
diagnosis of GC and CT in non-FDA-cleared anatomic specimens. Medical
Laboratory Observer 2006;38(7):10-15, 21-22.

Renault CA, Eckburg PB. An uncommon cause of malignant otitis externa.
Infections in Medicine 2005;22(11):566.

Eckburg PB, Schneider JJ, Renault CA. Avian influenza in humans: A
practical review for clinicians. Infections In Medicine
2005;22(11):535-542.

Kassaye S, Renault CA, Israelski DM. Book chapter: "Lower-Cost Laboratory Monitoring for CD4+ T-Lymphocyte Enumeration, HIV RNA Quantitation and Drug Resistance," From the Ground Up [in press].

Renault CA, Eckburg PB. Book chapter: "Infectious Diseases," Internal Medicine: Handbook for Clinicians: Resident Survival Guide [in press].

Renault CA, Hall C, Kent CK, Klausner JD. Use of NAATs for STD diagnosis of GC and CT in non-FDA-cleared anatomic specimens. Medical Laboratory Observer 2006;38(7):10-15, 21-22.

Renault CA, Eckburg PB. An uncommon cause of malignant otitis externa. Infections in Medicine 2005;22(11):566.

Eckburg PB, Schneider JJ, Renault CA . Avian influenza in humans: A practical review for clinicians. Infections In Medicine 2005;22(11):535-542.

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Frank Trinh

Frank Duy Trinh, MD (4th Year) grew up in Rockville , MD.   He received his medical training at the University of Maryland School of Medicine in Baltimore and stayed at the University of Maryland for his Internal Medicine residency.  After residency, he spent one year working as a hospitalist at the Martinsburg, WV VA Medical Center prior to starting his fellowship at Stanford.  His research interests include hepatitis B virus pathogenesis in monoinfected and HIV-coinfected individuals.  Current projects include a retrospective study evaluating the relationship between hepatitis B cccDNA and clinical outcomes and a prospective study investigating the relationship between hepatitis B and HIV genital shedding in coinfected patients. 
Mentor: Dennis M. Israelski, MD
 
Publications:
 
Toledano MB , I Kullik, F Trinh, PT Baird, TD Schneider, and G Storz.  “Redox-dependent shift of OxyR-DNA contacts along an extended DNA-binding site: a mechanism for differential promoter selection.”  Cell, 1994, Vol. 78, pp 897-909.
 
Toledano MB , D Ghosh, F Trinh, and WJ Leonard.  “N-Terminal DNA-binding domains
contribute to differential DNA-binding specificities of NF-kB p50 and p65.”  Molecular and Cellular Biology, 1993, Vol. 13, pp 852-860.

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Stephanie Barrett Troy

Stephanie Barrett Troy, who started her fellowship in July 2007, 
received her MD degree from the University of California at San Diego 
and completed her residency at the University of Illinois at Chicago.

Her research interests broadly include international health and HIV 
but will be further defined when she starts the research portion of 
her fellowship in July 2008.

List of Publications:

1. Troy SB, Rickman LS, and Davis CE.  Brucellosis in San Diego: 
Epidemiology and Species-Related Differences in Acute Clinical 
Presentations. Medicine. 2005;84:174-187.

2. Davis CE, Troy SB. Brucellosis.  The New England Journal of 
Medicine. 2005;353: 1071-1072.

3. Dapper G, Wallace DG, Yamamoto R, Barrett (Troy) S, Ly D, Nguyen M, 
Moravcsik P, Lifrieri J, Tran H, Reich C, and Sawyer PN.  Attachment 
of gelatin films to tissue using argon beam coagulator. Journal of 
Biomedical Materials Research: Applied Biomaterials. 1998;43(2):89-98.

4. Lahey J and Barrett (Troy) S.  Elective Chemistry Resource Manual 
for Teachers in Senior Secondary Schools.  Peace Corps Ghana.  May 1998.

 

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