2016

November

Ngan Huang presents a poster at the American Heart Association Scientific Sessions on: Co-Injection of Induced Pluripotent Stem Cell-Derived Endothelial Cells With Shear Thinning Hydrogel Enhances Survival and Angiogenesis In A Murine Model of Peripheral Arterial Disease

October

Karina Nakayama gives an oral presentation at the Biomedical Engineering Society Annual Conference on: Engineering Pre-Vascularized Skeletal Muscle with Physiologically-Relevant Cellular Organization for Treatment of Volumetric Muscle Loss

Ngan Huang presents a poster at the Biomedical Engineering Society Annual Conference on:Aligned Nanofibrillar Scaffolds for Controlled Delivery of Modified mRNA

September

Congratulations to Karina Nakayama for receiving the NIH F32 Postdoctoral Fellowship!

Congratulations to Maureen Wanjare for receiving an NIH Postdoctoral Diversity Supplement award!

Karina Nakayama received a travel award to present her research at the 5th Annual Symposium on Regenerative Rehabilitation in Atlanta, GA

Karina Nakayama gave an oral presentation at the 6th Tissue Engineering Symposium at Stanford University on: Engineering Pre-Vascularized Skeletal Muscle with Physiologically-Relevant Cellular Organization for Treatment of Volumetric Muscle Loss

August

The lab welcomes Guang Yang, the newest postdoc addition to our lab!

New! Lab publication from Luqia Hou in Acta Biomater that utilizes high throughout extracellular matrix microenvironments to understand the role of combinatorial extracellular matrices on the survival and phenotype of human induced pluripotent stem cell-derived endothelial cells.

July

The lab welcomes Cynthia Alcazar, our new lab manager and animal technician!

New! Lab publication from Joseph Kim and Luqia that reviews the bioengineering strategies for engineering vascularized three-dimensional cardiovascular tissue constructs.

Maureen Wanjare presented a poster at the Basic Cardiovascular Sciences (BCVS) 2016 Scientific Sessions.  Her poster is on: Engineered Anisotropic Substrates Promote the Function of Cocultured Cardiomyocytes Derived from Human Pluripotent Stem Cells.

Luqia Hou presented a poster at the Basic Cardiovascular Sciences (BCVS) 2016 Scientific Sessions.  His poster is on: ole of Combinatorial Extracellular Matrix Proteins in Modulating Endothelial Differentiation of Human Induced Pluripotent Stem Cells.

June

Ngan Huang is a co-author of a new publication in Science Translational Medicine that describes our opinion of the challenges and opportunities in cardiovascular tissue engineering. She is joined by other top researchers in the field like Gordana Vunjak-Novakovic, Milica Radisic, and Jay Zhang.

Along with our collaborators Stanley Rockson and Fibralign Corporation, we published the findings of a porcine study evaluating the therapeutic efficacy and safety of nanofibrillar scaffolds that release vascular endothelial growth factor-C for treatment of lymphedema  in Biomaterials.

This publication received some press from Stanford School of Medicine as well as other media outlets.

May

Karina Nakayama and Ngan Huang were featured in the Stanford Cardiovascular Institute 2016 Spring Quarterly Report for their recent publication in Nano Letters.

February

Ngan Huang receives a $1.5 million R01 grant from the NHLBI to study and apply nanofibrillar scaffolds for treatment of peripheral arterial disease

January

Department of Defense awards Fibralign Corporation and Ngan Huang a $1 million SBIR grant to translate nanofibrillar scaffolds for treatment of lower extremity vascular and muscular injuries.

Lab publication in collaboration with cardiothoracic surgery chair Dr. Y. Joseph Woo in Am J Physiol Heart Circ Physiol. 

2015

Karina Nakayama

Joseph Kim

Ngan Huang chaired two sessions at the BMES conference in  “Imaging in Cardiovascular Systems” and “Angiogenesis II”

September

Lab publication in collaboration with Dr. Phillip Yang and Rajesh Dash in J Am Heart Assoc.

July

Ngan Huang was selected to receive the McCormick Gabilan Faculty Fellowship.  This award is intended to support the advancement of women, and mentoring of women to pursue the study of medicine and medical research.

Karina Nakayama and Ngan Huang were featured in the Stanford Cardiovascular Institute 2015 Summer Quarterly Report for her recent publication in ACS Nano.

Veteran undergraduate researcher Nicholas Mezak was featured in the Veterans resource publication, G.I. Jobs, for his research in the Huang lab.  Nick strives to inspire other Veterans to pursue research biomedical careers.  

Ngan Huang was invited to give a presentation at the K-to-R01 Workshop at the NIH in Bethesda, MD

June

Karina Nakayama was awarded a postdoctoral fellowship from the American Heart Association.

Lab publication from Karina Nakayama in ACS Nano.

May

The Huang lab is represented at the ATVB/PVD Scientific Sessions in San Francisco.  Karina Nakayama presented an abstract on “Nanoscale Extracellular Matrix Alters Endothelial Function under Disturbed Flow.”  Luqia Hou presented an abstract on “Combinatorial Extracellular Matrix Microarrays for Probing Endothelial Differentiation of Human Induced Pluripotent Stem Cells.”

Ngan Huang is co-organizing the 2015 Cardiovascular Tissue Engineering Symposium at Stanford University.  Huang lab members are also represented in research posters.

February

We welcome Joseph Kim, a new postdoctoral fellow to the Huang lab.

Ngan Huang gave a guest seminar at the Cañada College STEM Speaker Series.

January

We welcome Maureen Wanjare, a new research associate to the Huang lab. 

We also welcome Monica Gole, a research volunteer to the Huang lab.

2014

December

Read our latest publication: Multi-cellular interactions sustain long-term contractility of human pluripotent stem cell-derived cardiomyocytes (Burridge, et al. Am J Trans Res, 2014). Link

November

The Huang lab was represented at the American Heart Association Scientific Sessions conference in Chicago, IL. 

Ngan Huang gave a talk on “Nanopatterned Extracellular Matrices Promote Endothelial Sprouting and Arteriogenesis in a Murine Model of Peripheral Arterial Disease.”  Her conference attendance was supported by a travel award from the Council for Peripheral Vascular Disease.

Karina Nakayama presented a poster on “3D Tri-culture Model Promotes Enhanced Mechanical Forces and Sustained Long-Term Contractility of Human Pluripotent Stem Cell-Derived Cardiomyocytes.”  Her conference attendance was supported by travel awards from the Stanford Cardiovascular Institute and the Council for Cardiovascular Surgery and Anesthesia.

August

We welcome Nick Mezak, a Veteran college student from Cañada College for a research internship in the Huang lab!

July

Congratulations to Karina Nakayama for being awarded a T32 postdoctoral fellowship!

Congratulations to the Huang lab for being selected for a CHEM-H New Materials Seed Grant in collaboration with the Sarah Heilshorn lab (Mat Sci & Eng). More

Ngan Huang was profiled in The Science Runway, to inspire the next generation of women leaders in healthcare and sciences. More

June

Welcome Prajakta Joshi, a CIRM fellow from San Jose State University, to the Huang laboratory!

Read our latest publication: Mulyasasmita W, Cai L, Dewi RE, Jha A, Ullmann SD, Luong RH, Huang NF, Heilshorn SC. Avidity-controlled hydrogels for injectable co-delivery of induced pluripotent stem cell-derived endothelial cells and growth factors. J Control Release. 2014. (epub) Pubmed

May

Ngan Huang received a travel award from the Peripheral Vascular Disease Council to present her abstract at the Arteriosclerosis Thrombosis and Vascular Biology Meeting Scientific Sessions, May 1-3, 2014, Toronto, Canada

April

We welcome Zachary Strassberg to join the Huang lab as a Life Sciences Research Assistant.

The Huang lab is represented at the Experimental Biology Conference in San Diego.  Luqia Hou will be presenting an abstract on “Extracellular Matrix-Mediated Differentiation of Human Induced Pluripotent Stem Cells.”

The Huang lab is represented at the 3rd Annual Symposium on Regenerative Rehabilitation in San Francisco.  Karina Nakayama is presenting an abstract on “Engineering Vascularized Skeletal Muscle with Physiologically-Relevant Cellular Organization.”

March

Congratulations to Luqia Hou for receiving a travel award from the Stanford Cardiovascular Institute for his abstract for the Experimental Biology Conference in San Diego in April.

A new exciting lab publication this month.  Read it here.

Hong G, Lee JC, Jha A, Diao S, Nakayama KH, Hou L, Doyle TC, Robinson JT, Antaris AL, Dai H, Cooke JP, Huang NF.  Near-Infrared II Fluorescence for Imaging Hindlimb Vessel Regeneration with Dynamic Tissue Perfusion Measurement. Circ Cardiovasc Imaging, 2014, (epub) Pubmed

Ngan Huang gave an invited lecture at the Department of Pharmaceutics and Pharmaceutical Chemistry Seminar Series at the University of Utah.  The talk was entitled, “Biophysical Regulation of Endothelial Cell Differentiation, Atheroprotection, and Survival”

February

Two new lab publications this month.  Read them here.

Ghebremariam YT, Huang NF, Kambhampati S, Volz KS, Joshi GG, Anslyn EV, Cooke JP. Characterization of a Fluorescent Probe for Imaging Nitric Oxide. J Vasc Surg, 51:68-79, 2014.Pubmed

Ostrowski MA, Huang NF, Walker TW, Verwijlen T, Poplawski C, Khoo AS, Cooke JP, Fuller GG, Dunn AR. Microvascular Endothelial Cells Migrate Upstream and Align Against the Shear Stress Field Created by Impinging Flow. Biophys J 106:366-374, 2014. Pubmed

Ngan Huang gave a talk at the ASME Global Congress on Nanoengineering for Medicine and Biology on “Anisotropic Nanofibrillar Collagen Modulates Endothelial Cell Morphology, Function, and Survival”

Ngan Huang was the instructor for the Stanford laboratory course, “Differentiation of Pluripotent Stem Cells into Cardiovascular Lineages” held at the Lokey Stem Cell Building.

January

Congrats to Karina Nakayama and Luqia Hou on their first publication in the Huang lab.  Read it here

Nakayama K, Hou L, Huang NF. Role of Extracellular Matrix Signaling Cues in Modulating Cell Fate Commitment for Cardiovascular Tissue Engineering. Adv Healthc Mater, 2014 (epub) Pubmed

2013

September

Welcome Arshi to the Huang lab as a Life Sciences Research Assisant!

August

Ngan Huang has a new publication in Arterioscler Thromb Vasc Biol.  Read it here!

Huang NF, Dewi RE, Okogbaa J, Lee JC, Rufaihah AJ, Heilshorn SC, Cooke, JC. Chemotaxis of human induced pluripotent stem cell-derived endothelial cells. Am J Transl Res 5:510-520, 2013. (*co-first author). Pubmed

June

Ngan Huang was the instructor for the Stanford laboratory course, “Differentiation of Pluripotent Stem Cells into Cardiovascular Lineages” held at the Lokey Stem Cell Building.

April

Ngan Huang gave a talk entitled, “Collagen Topographical Patterning Modulates Endothelial Cell Morphology, Gene Expression, And Function” at the Materials Research Society Spring Conference, San Francisco, CA.

Ngan Huang and Karina Nakayama co-lectured for MED223 course (Cardiovascular and Pulmonary Sciences Seminar) on the topic of “Stem Cell Approaches to Cardiovascular Tissue Engineering.”  The lecture was well-received by medical students and postdocs.

Ngan Huang attended the AHA Round Table Luncheon in Burlingame, CA, where significant funds were raised for research purposes.

March

Karina Nakayama joined the Huang lab as a postdoctoral fellow.  Welcome Karina!

Ngan Huang has a new publication in Arterioscler Thromb Vasc Biol.  Read them here!

Li J, Huang NF*, Zou J, Laurent TJ, Lee JC, Okogbaa J, Cooke JP, Ding S. Conversion of Human Fibroblasts to Functional Endothelial Cells by Defined Factors. Arterioscler Thromb Vasc Biol, 2013, epub. (*co-first author). Pubmed

February

Luqia Hou joined the Huang lab as a postdoctoral fellow.  Welcome Luqia!

Ngan Huang has a new publication in Biomaterials.  Read it here!

Huang NF, Okogbaa JN, Lee JC, Paukshto M, Zaitseva T, Cooke JP. The Modulation of Endothelial Cell Morphology, Function, and Survival Using Anisotropic Nanofibrillar Collagen Scaffolds.Biomaterials, 34: 4038-4047, 2013. Pubmed

January

Ngan Huang published 2 papers this month.  Read them here!

Jalil RA, Huang NF*, Kim J, Herold J, Volz KS, Park TS, Lee JC, Zambidis ET, Reijo-Pera R, Cooke, JP. Human Induced Pluripotent Stem Cell-Derived Endothelial Cells Exhibit Functional Heterogeneity. Am J Transl Res 2013 (in press) (*co-first author). Pubmed

Huang NF, Lai E, Fuller GG, Ribeiro AS, Pan S, Pruitt B, Fuller GG, Cooke JP. Spatial patterning and shear stress modulate endothelial cell morphology, gene expression, and function: implications for vascular tissue engineering. Biomaterials 34: 2928-2937, 2013. Pubmed