Research & Publications

Our Research

Overview

In addition to clinical and educational duties, our Hospitalists are active in the research community and we promote discoveries through innovative research and technology. Our focus areas include; inpatient hospital care, quality improvement and medical education.

Our faculty conduct research at Stanford University and Stanford ValleyCare and we are currently recruiting for clinical trials as part of the global response to COVID-19.

The Division of Hospital Medicine are actively involved in academic pursuits and publish in numerous prominent journals. We invite you to read more about our research below.

Clinical Trial Information

A Multicenter, Adaptive, Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Adults
Conducting a randomized, double-blind, placebo-controlled phase 2 trial to evaluate the safety and efficacy of the Ebola drug remdesivir in hospitalized adult patients diagnosed with COVID-19. The study is sponsored by the National Institutes of Health and is a multicenter trial that will be conducted at as many as 50 sites globally.

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate The Safety And Efficacy of Tocilizumab in Patients with Severe COVID-19 Pneumonia
Conducting a randomized, double-blind, placebo-controlled phase 3 trial to evaluate the safety and efficacy of tocilizumab, an interleukin-6 receptor antibody, in hospitalized adult patients diagnosed with severe COVID-19 pneumonia. This multicenter trial is being conducted at 65 sites globally.

Publications

2020

Slade J, Rohatgi N, Weng Y, Hom J, Ahuja N. Comparison of Outcomes for Adult Inpatients With Sickle Cell Disease Cared for by Hospitalists Versus Hematologists.

Rohatgi N, Weng Y, Ahuja N. Surgical Comanagement by Hospitalists: Continued Improvement Over 5 Years.

Li R, Marafino B, Nielsen D, Baiocchi M, Shieh L. Assessment of a Real-Time Locator System to Identity Physician and Nurse Locations.

Caton J, Penn E, Nemer M, Katz J, Yialamas MA. Getting Up to Speed: A Resident-Led Inpatient Curriculum for New Internal Medicine Interns.

Kumar A, Weng Y, Wang L, Bentley J, Almli M, Hom J, Witteles R, Ahuja N, Kugler J. Portable Ultrasound Device Usage and Learning Outcomes Among Internal Medicine Trainees: A Parallel-Group Randomized Trial.

2019

Rohatgi N, Wei PH, Grujic O, Ahuja N . Surgical co-management by hospitalists in colorectal surgery.

Ndichu E, Ohiri K, Sekoni O, Makinde O, Schulman K. Evaluation the quality of antihypersensetive drugs in Lagos State, Nigeria.

Wang J, Ouyang D, Hom J, Chi J, Chen J. Characterizing electronic health record usage patterns of inpatient medicine residents using event log data.

Kumar A, Chi J. CMS billing guidelines and student documentation: A new ear or new burden.

Schulman K, Milstein A. The implications of “Medicare for All” for US Hospitals.

Rudy M, Ahuja N. Acute kidney injury in lower extremity joint arthroplasty.

Ogbechie-Godec O, Wiske C, Schulman K. Decomposing the value of health insurance. Health Management Policy and Innovation.

Chin KK, Hom J, Tan M, Sharp C, Wang S, Chen YR, Chen D. Effect of electronic clinical decision support on 25 (OH) Vitamin D testing.

Zhu G, Li Y, Ding V, Jiang B, Ball RL, Rodriguez F, Fleischmann D, Desai M, Saloner D, Gupta A, Saba L, Hom J, Wintermark M. Semiautomated characterization of carotid artery plaque features from computerized tomography angiography to predict atherosclerotic cardiovascular disease risk score.

Alipanah N, Shete P, Nguyen H, Nguyen NV, Luu L, Pham Y, Nguyen H, Nguyen P, Tran MC, Pham N, Phan H, Phillips P, Cattamanachi A, Nahid P. Feasibility of direct sputum molecular testing for drug resistance as part of tuberculosis clinical trials eligibility screening.

Hom J, Marwaha S, Postolova A, Kittle J, Vaquez R, Davidson J, Kohler J, Dries A, Fernandez-Betancourt L, Majcherska M, Dearlove J, Raghavan S, Vogel H, Bernstein JA, Fisher P, Ashley E, Sampson J, Wheeler M, Undiagnosed Diseases Network. A patient with Sjorgren’s syndrome and subsequent diagnosis of inclusion body myositis and light-chain amyloidosis.

Kumar A, Kugler J, Jensen T. Evaluation of the trainee competency with point-of-care untrasonography (POCUS): A conceptual framework and review of existing assessments.

Li R, Wang JK, Sharp C, Chen J. When order sets do not align with clinician workflow: assessing practice patterns in the electronic health record.

Rohatgi N, Weng Y, Bentley J, Lansberg M, Shepard J, Mazur D, Ahuja N, Hopkins J. Initiative for Prevention and Early Identification for Delirium in Medical Surgical Units: Lessons Learned in the Past Five Years.

Rudy M, Bently J, Ahuja N, Rohatgi N. Determinants of cost variation in total hip and knee arthroplasty: implication for alternative payments models.

Schulman K, Milstein A, Barak D. Resolving Surprise Medical Bills.

2018

Chi J, Hosamani P. Is It Time To Re-Examine The Physical Exam?

Rudy M, Ahuja N, Aaronson A. Diabetes and Hyperglycemia in Lower-Extremity Total Joint Arthroplasty: Clinical Epidemiology, Outcomes, and Management.

Kane M, Rohatgi N, Heidenreich P, Thakur A, Winget M, Shum K, Hereford J, Shieh L, Lew T, Hom J, Chi J, Weinacker A, Seay-Morrison T, Ahuja N. Lean-Based Redesign of Multidisciplinary Rounds on General Medicine Service. Journal Of Hospital Medicine.

Kumar A, Liu G, Chi J, Kugler J. The Role of Technology in the Bedside Encounter.

Rohatgi N, Kane M, Winget M, Haji-Sheikhi F, Ahuja N. Factors Associated With Delayed Discharge on General Medicine Service at an Academic Medical Center.

Li Y, Zhu G, Ding V, Jiang B, Ball R, Ahuja N, Rodriguez F, Fleischmann D, Desai M, Saloner D, Saba L, Wintermark M, Hom J. Assessing the relationship between American Heart Association atherosclerotic cardiovascular disease risk score and coronary artery imaging findings.

Jun T, Kwang H, Mou E, Berbube C, Bentley J, Shieh L, Hom J. An Electronic best practice alert based on choosing wisely guidelines reduces Thrombophilia testing in the outpatient setting.

2017

Wang B, Svec D. Physicians and blocking: can we tear down this wall?

Garth M, Millet A, Shearer E, Stafford S., Merrell SB, Bruce J, Schillinger E, Aaronson A, Svec D. Interprofessional Collaboration: A Qualitative Studyof Non-Physician Perspectives on Resident Competency

Ahuja, N. Perioperative Medicine Meets Hospital Medicine, Lane Library, Stanford Medicine, Stanford University, 2017, Sep

Kroll H, Hom J, Ahuja N, Smith C, Wintermark M. R-SCAN: Imaging for Uncomplicated Acute Rhinosinusitis.

Hosamani P, Verghese A. Annals for Hospitalists Inpatient Notes - Rituals in Chaos

Ragavan M, Svec D, Shieh L. Barriers to Timely Discharge from the General Medicine Service at an Academic Teaching Hospital.

Kumar A, Chi J. The Illness of Present Histories.

Kittle J, Lopes R, Huang M, Marquess M, Wilson M, Ascher J, Krishen A, Hasselbald V, Kolls B, Roe M, McGuire D, Russell S, Mahaffey K. Cardiovascular Adverse Events in the Drug-Developed Program of Bupropion for Smoking Cessation: A Systematic Retrospective Adjudication Effort.

Hom J, Kumar A, Evans K, Svec D, Richman I, Fang D, Smeralgio A, Holubar M, Johnson T, Shah N, Renault C, Ahuja N, Witteles R, Harman S, Sheih L. A High Value Care Curriculum for Interns: A Description of Curricular Design, Implementation and Housestaff Feedback.

Chen J, Asch S. Machine Learning and Prediction in Medicine - Beyond the Peak of Inflated Expectations

2016

Lin S, Osborn K, Sattler A, Nelligan I, Svec D, Aaronson A, Schillinger E .Creating the medical school of the future through incremental curricular transformation: the Stanford Healthcare Innovations and Experiential Learning Directive (SHIELD).

Hom J, Richman I, Hall P, Ahuja N, Harman S, Harrington R, Witteles R. The State of Medical Student Performance Evaluations: Improved Transparency or Continued Obfuscation?

Mazer L, Storage T, Bereknyei S, Chi J, Skeff K. A Pilot Study of the Chronology of Present Illness: Restructuring the HPI to Improve Physician Cognitionand Communication.

Chen J, Goldstein M, Asch S, Mackey L, Altman R. Predicting inpatient clinical order patterns with probabilistic topic models vs conventional order sets.

Lembke A, Chen J .Use of Opioid Agonist Therapy for Medicare Patients in 2013.

Desautels T, Calvert J, Hoffman J, Jay M, Kerem Y, Shieh L, Shimabukuro D, Chettipally U, Feldman MD, Barton C, Wales D, Das R. Prediction of Sepsis in the Intensive Care Unit With Minimal Electronic Health Record Data: A Machine Learning Approach.

Chen J, Hom J, Richman I, Asch S, Podchiyska T, Johansen N. Effect of opioid prescribing guidelines in primary care. Medicine (Baltimore).

Rohatgi N, Loftus P, Grujic O, Cullen M, Hopkins J, Ahuja N. Surgical Comanagement by Hospitalists Improves Patient Outcomes: A Propensity Score Analysis.

Rolnick J, Downing NL, Shepard J, Chu W, Tam J, Wessels A, Li R, Dietrich B, Rudy M,Castaneda L, Shieh L. Validation of test performance and clinical time zero for an electronic health record embedded severe sepsis alert.

Hom J, Richman I, Chen J, Singh B, Crump C, Chi J. Fulfilling outpatient medicine responsibilities during internal medicine residency: a quantitative study of housestaff participation with between visit tasks.

Chen J. A PIECE OF MY MIND. The Patient You Least Want to See.

Ouyang D, Chen J, Krishnan G, Hom J, Witteles R, Chi J. Patient Outcomes When Housestaff Exceed Eighty Hours per Week.

Evans K, Ozdalga E, Ahuja N. The Medical Education of Generation Y.

Ahuja N, Ozdalga E, Aaronson A. Integrating Mobile Fitness Trackers into the Practice of Medicine. American Journal of Lifestyle Medicine.

Chi J, Artandi M, Kugler J, Ozdalga E, Hosamani P, Koehler E, Osterberg L, Zaman J, Thadaney S, Elder A, Verghese A. The Five-Minute Moment.

Chang A, Kittle J, Wu S. Regenerative Medicine: Potential Mechanisms of Cardiac Recovery in Takotsubo Cardiomyopathy Curr Treat Options Cardiovasc Med.

Chen J, Podchiyska T, Altman R. OrderRex: clinical order decision support and outcome predictions by data-mining electronic medical records.

Barroso V, Caceres W, Loftus P, Evans K, Shieh L. Hand hygiene of medical students and resident physicians: predictors of attitudes and behaviour.

Ouyang D, Chen J, Hom J, Chi J. Internal Medicine Resident Computer Usage: An Electronic Audit of an Inpatient Service.

Chen J, Humphreys, Shah N, Lembke A. Distribution of Opioids by Different Types of Medicare Prescribers.

2015

Svec D, Ahuja N, Evans K, Hom J, Garg T, Loftus P, Shieh L. Hospitalist intervention for appropriate use of telemetry reduces length of stay and cost.

Shieh L, Go M, Gessner D, Chen J, Hopkins J, Maggio P. Improving and sustaining a reduction in iatrogenic pneumothorax through a multifaceted quality-improvement approach.

Kantor MA, Evans K, Shieh L. Pending Studies at Hospital Discharge.

Garg T, Lee JY, Evans K, Chen J, Shieh L. Development and evaluation of an electronic health record-based best-practice discharge checklist for hospital patients.

Liao C, Thosani N, Kothari S, Friedland S, Chen A, Banerjee S. Radiation exposure to patients during ERCP is significantly higher with low-volume endoscopists.

Evans K, Daines W, Tsui J, Strehlow M, Maggio P, Shieh L. Septris: a novel, mobile, online, simulation game that improves sepsis recognition and management.

Gyang E, Shieh L, Forsey L, Maggio P. A nurse-driven screening tool for the early identification of sepsis in an intermediate care unit setting.

Chen J, Fang DZ, Tim Goodnough L, Evans K, Lee Porter M, Shieh L. Why providers transfuse blood products outside recommended guidelines in spite of integrated electronic best practice alerts.

2010

2011

2011

Verghese A, Charlton B, Cotter B, Kugler J.A history of physical examination texts and the conception of bedside diagnosis.

Shelby S, Ho C, Brooks E, Winslow DL, Kamal A, Doorley S. HIV and the Homeless: The Effect of Housing Status on HIV Disease Progression and Healthcare Access.

Nguyen CT, Aaronson A, Morrissey RP, Agarwal M, Willix RD, Schwarz ER. Myths and Truths of Growth Hormone and Testosterone Therapy in Heart Failure.

Aaronson AJ, Morrissey RP, Nguyen CT, Willix R, Schwarz ER. Update on the Safety of Testosterone Therapy in Cardiac Disease.

2012

2012

Andres Schuster, Akanksha Thakur, Zeneng Wang, Allen G. Borowski, James D. Thomas, MD,1 And W. H. Wilson Tang Increased Exhaled Nitric Oxide Levels After Exercise in Patients With Chronic Systolic Heart Failure With Pulmonary Venous Hypertension.

Ozdalga E, Ozdalga A, Ahuja N. The smartphone in medicine: a review of current and potential use among physicians and students.

Shao Z, Wang Z, Shrestha K, Thakur A, Borowski AG, Sweet W, Thomas JD, Moravec CS, Hazen SL, Tang WH. Pulmonary hypertension associated with advanced systolic heart failure: dysregulated arginine metabolism and importance of compensatory dimethylarginine dimethylaminohydrolase-1.

Detels RW, Winslow DL. Treatment as Prevention: Some Additional Thoughts (editorial).

2013

2013

Eisenberg M, Hom J, Sharp C. The electronic health record as a healthcare management strategy and implications for obstetrics and gynecologic practice.

Chi J, Verghese A. Improving communication with patients: learning by doing.

Tan M, Hooper Evans K, Braddock CH 3rd, Shieh L. Patient whiteboards to improve patient-centred care in the hospital.

Elder A, Chi J, Ozdalga E, Kugler J, Verghese A. A piece of my mind. The road back to the bedside.

Kochar, R, Liao, C, et al. Patient Radiation Exposure During ERCP Can Be Successfully Reduced by Education of Endoscopists: Prospective Evaluation of the Impact of an Educational Program.

Aaronson A, Kittleson M, Patel J, Rafiei M, Osborne A, Chang D, Czer L, Kobashigawa J. Benefit of Tacrolimus/Mycophenolate to Reduce Cardiac Allograft Vasculopathy after Heart Transplantation.

2014

2014

Fang DZ, Sran G, Gessner D, Loftus PD, Folkins A, Christopher JY 3rd, Shieh L. Cost and turn-around time display decreases inpatient ordering of reference laboratory tests: a time series.

Chi J, Verghese A. Clinical education and the electronic health record: the flipped patient.

Chi J, Kugler J, Chu IM, Loftus PD, Evans KH, Oskotsky T, Basaviah P, Braddock CH 3rd. Medical students and the electronic health record: 'an epic use of time'.

Przybylo JA, Wang A, Loftus P, Evans KH, Chu I, Shieh L. Smarter hospital communication: secure smartphone text messaging improves provider satisfaction and perception of efficacy, workflow.

Shao Z, Zhang R, Shrestha K, Borowski AG, Schuster A, Thakur A, Hazen SL, Tang WH. Usefulness of Elevated Urine Neopterin Levels in Assessing Cardiac Dysfunction and Exercise Ventilation Inefﬁciency in Patients With Chronic Systolic Heart Failure.

Thosani, N, Liao, C, et al. Delivery of Monthly Patient Radiation Exposure Report Cards to Endoscopists Significantly Reduces Patient Radiation Exposure During ERCP: a Prospective Quality Improvement Study.

Chen JH, Altman RB. Automated physician order recommendations and outcome predictions by data-mining electronic medical records.

Thakur A, Witteles RM. Cancer Therapy-Induced Left Ventricular Dysfunction: Interventions and Prognosis.

Shieh L, Chi J, Kulik C, Momeni A, Shelton A, DePorte C, Hopkins J. Assigning a team-based pager for on-call physicians reduces paging errors in a large academic hospital.

Batniji R, Khatib L, Cammett M, Sweet J, Basu S, Jamal A, Wise P, Giacaman R. Governance and health in the Arab world.

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