Clinical Research

Our
Clinical
Research

Serum and cellular biomarkers to predicting disease activity in MS and Neuromyelitis optica

Blood and imaging biomarkers to predict disease activity in MS

Cognitive impairment in MS

The Collaborative International Research in Clinical and Longitudinal Experience for Neuromyelitis Optica (NMO) Studies (CIRCLES)

Neuromyelitis
Optica
(NMO)

Is an inflammatory demyelinating disorder of the Central Nervous System (CNS) primarily affecting the optic nerve and spinal cord. Individuals suffering from NMO mainly present with vision impairment, weakness and paralysis, and bladder and bowel problems. NMO patients most often have relapses and progressive neurologic disability.

Collaborative
International
Research

The Collaborative International Research in Clinical and Longitudinal Experience for Neuromyelitis Optica (NMO) Studies (CIRCLES) is a study that aims to create an open-access repository of data and samples from participants with NMO and from control participants.  These materials are intended to be used in research to better understand:

  • NMO Pathogenesis,
  • Clinical Course
  • Impact of Therapy

Results of these studies may identify:

  • The etiology and risk factors
  • Biomarkers for disease progression
  • Treatment outcomes to guide development of novel therapies

Findings may also facilitate future research and clinical trials to investigate specific hypotheses related to NMO and to improve the lives of individuals suffering from NMO.

Clinical Trials

Blood, CSF and Tissue Repository To Identify Biomarkers in Multiple Sclerosis
Stanford Protocol #16691
Sponsor: Stanford University
PI: May Han, MD
Study Active, Enrollment Open

Clinical Trials Contact:

Kara Richardson
Co-Manager, Stanford Neuroscience Clinical Research Group
Clinical Research Coordinator
Neurosurgery and Neurology Departments
Stanford School of Medicine
(650) 736-6171

Clinical Research Questions?

For more information regarding the Han Lab Clinical Reseach:

Anna Tomczak
Clinical Research Coordinator, CIRCLES Study
Phone: 650-721-8489
Cell: 650-796-8420
Fax: 650-498-6262
Email: atomc96@stanford.edu

Mike Feng
Clinical Research Coordinator, CIRCLES Study
Phone: 650-721-8490
Cell: 650-529-5935
Fax: 650-498-6262
Email: fengh@stanford.edu

Guthy-Jackson Charitable Foundation

 

This work is funded by the Guthy-Jackson Charitable Foundation for NMO research.

We are currently recruiting participants for the CIRCLES study.

Participants will answer patient questionnaires and donate blood samples.