Meet Our Team
Alakananda Das, Ph.D.
Ph.D.: University of North Carolina at Chapel Hill
Year started in lab: 2016
Project Title: Studying the relationship between integrins, ion channels and extracellular matrix in C. elegans touch sensation.
Expertise: Worm genome editing, protein structure and function.
I am interested in studying the molecular basis of how cells sense and interact with their environment. In particular I am studying the process of mechanosensation in worms. I want to work out the molecular details of whether there is a cross-talk between different kinds of cellular mechanoreceptors and the degree of their interdependence.
Sylvia Fechner, Ph.D.
Ph.D.: Rheinische Friedrich-Wilhelms-University
Year started in lab: 2014
Project Title: Investigating the stoichiometry of the ion channel pore units underlying touch sensation with structural-functional studies
Expertise: Patch-Clamp experiments with tiny cells from sperm to neurons
As I became really fond of ion channels, I decided to do my PostDoc in the lab of Dr. Miriam Goodman at Stanford. Here, I study the role of ion channels and their stoichiometry in touch receptor neurons of the nematode C. elegans. I use piezoresistive cantilevers to apply controlled mechanical loads combined with the patch-clamp technique to record the neuronsâ€™ response (setup name: FALCON). From whole brain recordings, via patch-clamping zebrafish sperm to mechanosensitive neurons in C. elegans, I am curious what the future targets will be.
Holger Fehlauer, Ph.D.
Ph.D.: Leibniz University of Hannover
Year started in lab: 2015
Project Title: Investigation of neuronal activity in complex systems
Expertise: Fluorescence (single-molecule) microscopy, Microfluidics, Calcium imaging, Image and data analysis with ImageJ and Python
For my Postdoc I joined Dr. Goodman’s lab at Stanford University. Here I investigate the neuronal activity of two sets of neurons in C. elegans: the response of touch receptor neurons to different touch stimuli, and of neurons involved in food - salt associative learning to salt. I am fascinated how elegant the nervous system of a “simple” organism is able to distinguish between small differences in stimuli, habituate and learn.
Sammy is studying how membrane composition and mechanoreceptor channel structure govern touch sensitivity. She graduated from UC Berkeley in 2011 with a B.A. in Molecular and Cell Biology and a minor in Global Poverty and Practice. At Stanford, Sammy helped found the scicomm group NeuWrite West for students who wanted science to be understandable to the public (www.neuwritewest.org). In her spare time, she is also president of the Stanford Jujitsu Club.
BS Degree: University of Calfornia, Berkeley
Year started in lab: 2013
Project Title: Molecular and cellular role of CMK-1 in associative learning
Expertise: Chemosensation, worm behavior
Jana is a PhD candidate who is co-advised by Drs. Anne Brunet and Miriam Goodman. The roots of her scientific interests run deep, from her high school days of pollinating roses in her father's research greenhouses, to studying trans-generational epigenetic inheritance in maize at UC Berkeley. Currently, Jana is dissecting the role of a kinase in associative learning in C. elegans, an organism with far fewer neurons than mice yet a great toolkit for understanding basic mechanisms of behavioral plasticity. Outside of lab, Jana is a traveler and an aspiring yogi.
I'm a PhD student co-mentored by Beth Pruitt and Miriam Goodman. My background is in mechanical engineering, but I am venturing into the world of biological research. My research interests focus on understanding how the mechanical properties of the worm's tissues affect its ability to sense touch stimuli. Outside the lab, I enjoy spending time biking, hiking, skiing, and running in the California sunshine.
Zhiwen (Carmen) Liao
Year started in the lab: 2002
Expertise: Oocyte isolation, C. elegans husbandry, freezing/thawing worms, TEVC of oocytes, C. elegans genetics, C. elegans transgenesis, measuring surface expression of membrane proteins expressed in oocytes, cRNA synthesis, plasmid propagation and maintenance.
Born and grew up in Guangzhou, China. Came to the Golden State in 2000. Became a worm sensorian soon after till now.
I began my academic career as a marine biologist working on algae, but switched to cell and molecular biology for my PhD. I completed my thesis work in 1986 on mammalian rod photoreceptor development, examining disc development. After a post-doc at U Penn, I started working for Howard Hughes Medical Institute in 1989 in the lab of Corey Goodman at UC Berkeley on aspects of neuronal pathfinding and neuromuscular development by electron microscopy. Subsequently I worked in Cori Bargmann's lab at UCSF and The Rockefeller University on C. elegans. In 2007 I was asked to set up and run the EM facility at HHMI's Janelia Research Campus in Ashburn, VA. In August 2015 I retired from HHMI and returned to the Bay Area where I currently provide EM support for labs at Stanford and UCSF.
|Austin L. Brown||2002-2007||National Renewable Energy Laboratory|
|Joseph C. Doll||2006-2012||Apple, Inc.|
|Brandon E. Johnson||2004-2010||Menlo College|
|Eileen Mazzochette||2012-2016||Apple, Inc.|
||2004-2009||Research Associate, Harvard University|
|Bryan Petzold||2007-2013||McKinsey & Company|
|Daniel Ramot||2002-2007||Co-founder & CEO, Via|
|Dean Lockhead||2010-2016||Consulting Associate, Charles River Associates|
|Juan Cueva||2003-2009||Co-founder, Curium; Scientist, Aratome|
|Amy L. Eastwood||2008-2013|
|Shana L. Geffeney||2005-2011||Lecturer, Utah State University- Uintah Basin|
|Dominique A. Glauser||2008-2010||SNSF Associate Professor, Freiburg University, Switzerland|
|Diana Koulechova||2014-2015||Senior Scientist II, Boehringer-Ingleheim, Inc.|
||2015-2017||Postdoctoral Research Fellow, Stanford Radiological Sciences Laboratory||CAP Profile|
|Samuel Lasse||2011-2014||Technical Support Specialist, Fluidigm, Inc.|
|Bronwyn L. MacInnis||2004-2008||Assistant Director, Malaria Research, Broad Insitute|
|Valeria Vasquez||2009-2014||Assistant Professor, University of Tennessee Medical Center|
|Dong Wang||2009-2012||Staff Scientist, Anesthesiology, Stanford University
|Michael Krieg||2011-2016||Groupleader/Professor at The Institute of Photonic Sciences, Barcelona|