Dry Lab Research
Arden Morris, MD
The colorectal surgery program is actively engaged in a wide variety of research endeavors including health services and disparities research projects, clinical trials, and outcomes research.
The colorectal surgeons see patients at the Stanford Cancer Center. Their clinical profiles can be found at this site by entering the "Find a Physician" link.
All four bariatric surgery faculty members (Drs. Dan Azagury, James Lau, John Morton and Homero Rivas) and both fellows have been very involved in a number of clinical research projects which have focused mostly on the outcomes of our bariatric surgery program. We currently have a prospective randomized trial evaluating the use of preoperative weight loss prior to bariatric surgery. In addition, we have looked at our results evaluating the learning curve of the operation when the surgeon's training differs and when the assistant's training differs. We are currently implementing a study to evaluate hand sewn versus stapled anastomosis.
- Dr. Ralph Greco, in collaboration with Mechanical Engineering and the Stanford Rapid Prototyping facility, is studying methods to use nanoscale technology to fabricate new biomaterials for drug delivery and tissue engineering.
- Dr. Stefanie Jeffrey continues her nationally recognized work into the molecular genetics of breast cancer and is co-investigator of an NIH grant.
- Dr. Jeffrey Norton was just awarded an NIH grant to study tumor immunology. The grant is looking at methods to potentiate the immune response against murine tumors, specifically by inhibiting STAT6 and administering interleukin-12.
- Dr. Irene Wapnir is the Principal Investigator for the National Surgical Adjuvant Breast and Bowel Project sponsored clinical trials at Stanford and is study chair of a new national protocol seeking to define the optimal treatment for women with locally recurrent breast cancer (NSABP B-37) http://www.nsabp.org . The pursuit of new strategies and novel therapies through advances in molecular biology will contribute to the goal of achieving lasting cures in breast cancer. A decade ago the protein responsible for the transport of iodine in the thyroid gland was finally cloned. Dr Wapnir and her colleagues went on to discover that many breast cancers express the sodium iodide symporter ( NIS ). Moreover, they have now shown for the first time that some breast cancers, like thyroid cancers, could be treated with radioactive iodine. Studies are under way at Stanford to test the feasibility of this approach and determine its clinical usefulness. In addition to her role in the NSABP clinical trials, has been funded to continue her creative research into the role of the sodium iodide transporter in breast cancer and potential treatment strategies that may evolve from this work.
- Dr. George Yang's research has a primary emphasis on research into tissue engineering. He was recently awarded a 5 yr KO8 training grant to pursue this topic.
- Dr. Samuel So is the head of the Asian Liver Center at Stanford researching genomics of hepatocellular carcinoma.
- Dr. Fred Dirbas has opened a new clinical trial evaluating the feasibility of intra-operative radiation therapy for breast cancer.