Publications
- Brittany M. Flowers, Huang Xu, Abigail S. Mulligan, Kathryn J. Hanson, Jose A. Seoane, Hannes Vogel, Christina Curtis and Laura D. Wood, 2021, Cell of Origin Influences Pancreatic Cancer Subtype, Cancer Discovery,
- Zhang Z, Denans N, Liu Y, Zhulyn O, Rosenblatt HD, Wernig M and Barna M, 2021, Optogenetic manipulation of cellular communication using engineered myosin motors., Nature cell biology, 23:198-208
- Heller IS, Guenther CA, Meireles AM, Talbot WS and Kingsley DM, 2021, Characterization of mouse Bmp5 regulatory injury element in zebrafish wound models., BioRxiv
- Ho EK, Stearns T., 2021, Hedgehog signaling and the primary cilium: implications for spatial and temporal constraints on signaling., Development. 148(9):dev195552
- Senaratne AP, Muller H, Fryer KA, Kawamoto M, Katsuma S and Drinnenberg IA, 2021, Formation of the CenH3-Deficient Holocentromere in Lepidoptera Avoids Active Chromatin., Current biology : CB, 31:173-181.e7
- Smith OK, Limouse C, Fryer KA, Teran NA, Sundararajan K, Heald R, Straight AF, 2021, Identification and characterization of centromeric sequences in Xenopus laevis., Genome Res. gr.267781.120. doi: 10.1101/gr.267781.120.
- Zhang S, Zhang X, Purmann C, Ma S, Shrestha A, Davis KN, Ho M, Huang Y, Pattni R, Wong WH, Bernstein JA, Hallmayer J and Urban AE, 2021, Network Effects of the 15q13.3 Microdeletion on the Transcriptome and Epigenome in Human-Induced Neurons., Biological psychiatry, 89:497-509
- Jordan Myers, Muthukumar Ramanathan, Ronald Shanderson, Laura Donohue, Ian Ferguson, Margaret Guy, Deepti Rao, Weili Miao, David Reynolds, Yang Zhao, Yen Yu Yang, Yinsheng Wang and Paul Khavari, 2021, The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation, BioRxiv,
- Porter DF, Miao W, Yang X, Goda GA, Ji AL, Donohue LKH, Aleman MM, Dominguez D and Khavari PA, 2021, easyCLIP analysis of RNA-protein interactions incorporating absolute quantification., Nature communications, 12:1569
- Thomas R. Ward, Xianglong Zhang, Louis C. Leung, Bo Zhou, Kristin Muench, Julien G. Roth, Arineh Khechaduri, Melanie J. Plastini, Carol Charlton, Reenal Pattni, Steve Ho, Marcus Ho, Yiling Huang, Joachim F. Hallmayer, Phillippe Mourrain, Theo D. Palmer and Alexander E. Urban, 2020, Genome-wide molecular effects of the neuropsychiatric 16p11 CNVs in an iPSC-to-iN neuronal model, Biorxiv, https://doi.org/10.1101/2020.02.09.940965
- Limouse C, Jukam D, Smith OK, Fryer KA and Straight AF, 2020, Mapping Transcriptome-Wide and Genome-Wide RNA-DNA Contacts with Chromatin-Associated RNA Sequencing (ChAR-seq). Methods in molecular biology (Clifton, N.J.), 2161:115-142
- Wells KL, Miller CN, Gschwind AR, Wei W, Phipps JD, Anderson MS and Steinmetz LM, 2020, Combined transient ablation and single-cell RNA- sequencing reveals the development of medullary thymic epithelial cells., eLife, 9
- Ho EK, Tsai AE, Stearns T., 2020, Transient primary cilia mediate robust Hedgehog pathway-dependent cell cycle control, Current Biology, 30(14):2829-2835.e5.
- Koyama LAJ, Aranda-Díaz A, Su YH, Balachandra S, Martin JL, Ludington WB, Huang KC and O'Brien LE, 2020, Bellymount enables longitudinal, intravital imaging of abdominal organs and the gut microbiota in adult Drosophila., PLoS biology, 18:e3000567
- Fouracre JP, Kohler A, Amador G and Fung HF. 2020. FASEB: The mechanisms in plant development. The New Phytologist, 225:2243-2245
- Helle E, Ampuja M, Dainis A, Antola L, Temmes E, Mervaala E and Kivela R. 2020. Modeling cellular crosstalk and organotypic vasculature development with human iPSC-derived endothelial cells and cardiom. https://doi.org/10.1101/2020.05.04.075846
- Wenderski W, Wang L, Krokhotin A, Walsh JJ, Li H, Shoji H, Ghosh S, George RD, Miller EL, Elias L, Gillespie MA, Son EY, Staahl BT, Baek ST, Stanley V, Moncada C, Shipony Z, Linker SB, Marchetto MCN, Gage FH, Chen D, Sultan T, Zaki MS, Ranish JA, Miyakawa T, Luo L, Malenka RC, Crabtree GR and Gleeson JG. 2020. Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism. Proceedings of the National Academy of Sciences of the United States of America.
- Braun S, Petrova R, Tang J, Krokhotin A, Miller EL, Tang Y and Panagiotakos G. 2020. The npBAF to nBAF Chromatin Switch Regulates Cell Cycle Exit in the Developing Mammalian Cortex. BioRxiv, https://doi.org/10.1101/2020.01.17.910794
- Sapiro AL, Freund EC, Restrepo L, Qiao HH, Bhate A, Li Q, Ni JQ, Mosca TJ and Li JB. 2020. Zinc Finger RNA-Binding Protein Zn72D Regulates ADAR-Mediated RNA Editing in Neurons. Cell Reports, 31:107654
- Sarkar TJ, Quarta M, Mukherjee S, Colville A, Paine P, Doan L, Tran CM, Chu CR, Horvath S, Qi LS, Bhutani N, Rando TA and Sebastiano V. 2020. Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells. Nature Communications, 11:1545
- Zhang X*, Hong D*, Ma S*, Ward T, Ho M, Pattni R, Duren Z, Stankov A, Bade Shrestha S, Hallmayer J, Wong WH, Reiss AL and Urban AE. 2020. Integrated functional genomic analyses of Klinefelter and Turner syndromes reveal global network effects of altered X chromosome dosage. Proceedings of the National Academy of Sciences of the United States of America, 117:4864-4873 (*Co-first author)
- Koyama LAJ, Aranda-Díaz A, Su YH, Balachandra S, Martin JL, Ludington WB, Huang KC and O'Brien LE. 2020. Bellymount enables longitudinal, intravital imaging of abdominal organs and the gut microbiota in adult Drosophila. PLoS Biology, 18:e3000567
- Dainis, A, Tseng, E, Clark, TA, Hon, T, Wheeler, M and Ashley, E. Targeted Long-Read RNA Sequencing Demonstrates Transcriptional Diversity Driven by Splice-Site Variation in MYBPC3. Circ Genom Precis Med, 2019; 12 5, e002464.
- Xie KT, Wang G, Thompson AC, Wucherpfennig JI, Reimchen TE, MacColl ADC, Schluter D, Bell MA, Vasquez KM, Kingsley DM. DNA fragility in the parallel evolution of pelvic reduction in stickleback fish. Science. 2019 Jan 4;363(6422):81-84. doi: 10.1126/science.aan1425. Epub 2019 Jan 3. PMID: 30606845 PMCID: PMC6677656
- Julia I. Wucherpfennig, Craig T. Miller and David M. Kingsley. 2019. Efficient CRISPR-Cas9 editing of major evolutionary loci in sticklebacks. Evolutionary Ecology Research, 20
- Chang ACY, Chang ACH, Kirillova A, Sasagawa K, Su W, Weber G, Lin J, Termglinchan V, Karakikes I, Seeger T, Dainis AM, Hinson JT, Seidman J, Seidman CE, Day JW, Ashley E, Wu JC, Blau HM. 2018. Telomere shortening is a hallmark of genetic cardiomyopathies. Proc Natl Acad Sci U S A.115(37):9276-81. Epub 2018/08/29. doi: 10.1073/pnas.1714538115. PubMed PMID: 30150400. PMCID: PMC6140486
- Meireles AM, Shen K, Zoupi L, Iyer H, Bouchard EL, Williams A, Talbot WS. The Lysosomal Transcription Factor TFEB Represses Myelination Downstream of the Rag-Ragulator Complex. Dev Cell. 2018 Nov 5;47(3):319-330.e5. doi: 10.1016/j.devcel.2018.10.003. PMID: 30399334 PMCID: PMC6250074
- Lin, M, Siford, RL, Martin, AR, Nakagome, S, Moller, M, Hoal, EG, Bustamante, CD, Gignoux, CR and Henn, BM Rapid evolution of a skin-lightening allele in southern African KhoeSan. Proc Natl Acad Sci U S A, 2018; 115 52, 13324-13329. PMC6310813
- Chen HI, Jagadeesh KA, Birgmeier J, Wenger AM, Guturu H, Schelley S, Bernstein JA, Bejerano G. An MTF1 binding site disrupted by a homozygous variant in the promoter of ATP7B likely causes Wilson Disease. Eur J Hum Genet. 2018 Dec;26(12):1810-1818. doi: 10.1038/s41431-018-0221-4. Epub 2018 Aug 7. PMID: 30087448 PMC6244090
- Liu N, Lee CH, Swigut T, Grow E, Gu B, Bassik MC, Wysocka J. 2018. Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators. Nature.553(7687):228-32. Epub 2017/12/07. doi: 10.1038/nature25179. PubMed PMID: 29211708; PubMed Central PMCID: PMC5774979.
- Martin JL, Sanders EN, Moreno-Roman P, Jaramillo Koyama LA, Balachandra S, Du X, O'Brien LE. Long-term live imaging of the Drosophila adult midgut reveals real-time dynamics of division, differentiation and loss. Elife. 2018 Nov 14;7. pii: e36248. doi: 10.7554/eLife.36248. PMID: 30427308 PMCID: PMC6277200
- Chen HI, Jagadeesh KA, Birgmeier J, Wenger AM, Guturu H, Schelley S, Bernstein JA, Bejerano G. An MTF1 binding site disrupted by a homozygous variant in the promoter of ATP7B likely causes Wilson Disease. Eur J Hum Genet. 2018 Dec;26(12):1810-1818. doi: 10.1038/s41431-018-0221-4. Epub 2018 Aug 7. PMID: 30087448 PMC6244090
- Zhang, X, Zhang, Y, Zhu, X, Purmann, C, Haney, MS, Ward, T, Khechaduri, A, Yao, J, Weissman, SM and Urban, AE Local and global chromatin interactions are altered by large genomic deletions associated with human brain development. Nat Commun, 2018; 9 1, 5356. PMC6297223
- Wojcik GL, Fuchsberger C, Taliun D, Welch R, Martin AR, Shringarpure S, Carlson CS, Abecasis G, Kang HM, Boehnke M, Bustamante CD, Gignoux CR, Kenny EE. 2018. Imputation-Aware Tag SNP Selection To Improve Power for Large-Scale, Multi-ethnic Association Studies. G3 (Bethesda). Epub 2018/08/23. doi: 10.1534/g3.118.200502. PubMed PMID: 30131328. PMCID: PMC6169386
- Dainis AM, Ashley EA. 2018. Cardiovascular Precision Medicine in the Genomics Era. JACC Basic Transl Sci.3(2):313-26. Epub 2018/08/01. doi: 10.1016/j.jacbts.2018.01.003. PubMed PMID: 30062216; PubMed Central PMCID: PMC6059349.
- Liu, N, Lee, CH, Swigut, T, Grow, E, Gu, B, Bassik, MC and Wysocka, J. Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators. Nature, 2018; 553 7687, 228-232. PMC5774979
- Miller, CN, Proekt, I, von Moltke, J, Wells, KL, Rajpurkar, AR, Wang, H, Rattay, K, Khan, IS, Metzger, TC, Pollack, JL, Fries, AC, Lwin, WW, Wigton, EJ, Parent, AV, Kyewski, B, Erle, DJ, Hogquist, KA, Steinmetz, LM, Locksley, RM and Anderson, MS Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development. Nature, 2018; 559 7715, 627-631. PMC6062473
- Ohsawa*S., Vaughen* J., and Igaki, T. Cell extrusion: a stress-responsive force for good or evil in epithelial homeostasis. (2018). Dev. Cell 44, 284–296. * = co-first author PMID: 29408235 PMCID: PMC6207186
- Yucel, N, Chang, AC, Day, JW, Rosenthal, N and Blau, HM Humanizing the mdx mouse model of DMD: the long and the short of it. NPJ Regen Med, 2018; 3 4. PMC5816599
- Chang, ACY, Chang, ACH, Kirillova, A, Sasagawa, K, Su, W, Weber, G, Lin, J, Termglinchan, V, Karakikes, I, Seeger, T, Dainis, AM, Hinson, JT, Seidman, J, Seidman, CE, Day, JW, Ashley, E, Wu, JC and Blau, HM Telomere shortening is a hallmark of genetic cardiomyopathies. Proc Natl Acad Sci U S A, 2018; 115 37, 9276-9281. PMC6140486
- Koh AS, Miller EL, Buenrostro JD, Moskowitz DM, Wang J, Greenleaf WJ, Chang HY, Crabtree GR. 2018. Rapid chromatin repression by Aire provides precise control of immune tolerance. Nat Immunol.19(2):162-72. Epub 2018/01/18. doi: 10.1038/s41590-017-0032-8. PubMed PMID: 29335648; PubMed Central PMCID: PMC6049828.
- Kramer NJ, Haney MS, Morgens DW, Jovicic A, Couthouis J, Li A, Ousey J, Ma R, Bieri G, Tsui CK, Shi Y, Hertz NT, Tessier-Lavigne M, Ichida JK, Bassik MC, Gitler AD. 2018. CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity. Nat Genet.50(4):603-12. Epub 2018/03/07. doi: 10.1038/s41588-018-0070-7. PubMed PMID: 29507424; PubMed Central PMCID: PMC5893388.
- Daugherty AC, Yeo RW, Buenrostro JD, Greenleaf WJ, Kundaje A, Brunet A. 2017. Chromatin accessibility dynamics reveal novel functional enhancers in C. elegans. Genome Res.27(12):2096-107. Epub 2017/11/17. doi: 10.1101/gr.226233.117. PubMed PMID: 29141961; PubMed Central PMCID: PMC5741055.
- Kadoch C, Williams RT, Calarco JP, Miller EL, Weber CM, Braun SM, Pulice JL, Chory EJ, Crabtree GR. Dynamics of BAF-Polycomb complex opposition on heterochromatin in normal and oncogenic states. Nature genetics. 2017;49(2):213-22. doi: 10.1038/ng.3734. PubMed PMID: 27941796; PubMed Central PMCID: PMC5285326.
- Chang AH, Raftrey BC, D'Amato G, Surya VN, Poduri A, Chen HI, Goldstone AB, Woo J, Fuller GG, Dunn AR, Red-Horse K. DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12-CXCR4 signaling axis. Genes & development. 2017. doi: 10.1101/gad.301549.117. PMID: 28779009; PMCID: PMC5580653. Free PMC Article
- Cheng MH, Andrejka L, Vorster PJ, Hinman A, Lipsick JS. The Drosophila LIN54 homolog Mip120 controls two aspects of oogenesis. Biology open. 2017;6(7):967-78. doi: 10.1242/bio.025825. PubMed PMID: 28522430; PubMed Central PMCID: PMC5550918.
- Alcantara D, Timms AE, Gripp K, Baker L, Park K, Collins S, Cheng C, Stewart F, Mehta SG, Saggar A, Sztriha L, Zombor M, Caluseriu O, Mesterman R, Van Allen MI, Jacquinet A, Ygberg S, Bernstein JA, Wenger AM, Guturu H, Bejerano G, Gomez-Ospina N, Lehman A, Alfei E, Pantaleoni C, Conti V, Guerrini R, Moog U, Graham JM, Jr., Hevner R, Dobyns WB, O'Driscoll M, Mirzaa GM. Mutations of AKT3 are associated with a wide spectrum of developmental disorders including extreme megalencephaly. Brain : a journal of neurology. 2017;140(10):2610-22. doi: 10.1093/brain/awx203. PubMed PMID: 28969385. PMCID: PMC6080423
- Byers JS, Jarosz DF. High-throughput Screening for Protein-based Inheritance in S. cerevisiae. Journal of visualized experiments : JoVE. 2017(126). doi: 10.3791/56069. PubMed PMID: 28809826. PMC5614125.
- Low YS, Daugherty AC, Schroeder EA, Chen W, Seto T, Weber S, Lim M, Hastie T, Mathur M, Desai M, Farrington C, Radin AA, Sirota M, Kenkare P, Thompson CA, Yu PP, Gomez SL, Sledge GW, Jr., Kurian AW, Shah NH. Synergistic drug combinations from electronic health records and gene expression. Journal of the American Medical Informatics Association : JAMIA. 2017;24(3):565-76. doi: 10.1093/jamia/ocw161. PubMed PMID: 27940607 PMCID: PMC6080645
- Martin AR, Lin M, Granka JM, Myrick JW, Liu X, Sockell A, Atkinson EG, Werely CJ, Moller M, Sandhu MS, Kingsley DM, Hoal EG, Liu X, Daly MJ, Feldman MW, Gignoux CR, Bustamante CD, Henn BM. 2017. An Unexpectedly Complex Architecture for Skin Pigmentation in Africans. Cell.171(6):1340-53 e14. Epub 2017/12/02. doi: 10.1016/j.cell.2017.11.015. PubMed PMID: 29195075; PubMed Central PMCID: PMC5884124
- Sharma B, Ho L, Ford GH, Chen HI, Goldstone AB, Woo YJ, Quertermous T, Reversade B, Red-Horse K. Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts. Developmental cell. 2017;42(6):655-66 e3. doi: 10.1016/j.devcel.2017.08.008. PMID: 28890073. PMCID: PMC5895086.
- Perez AM, Mann TH, Lasker K, Ahrens DG, Eckart MR, Shapiro L. A Localized Complex of Two Protein Oligomers Controls the Orientation of Cell Polarity. MBio. 2017 Feb 28;8(1). pii: e02238-16. doi: 10.1128/mBio.02238-16. PMID: 28246363 PMCID: PMC5347347
- Silas S, Jain N, Stadler M, Fu BXH, Sanchez-Amat A, Fire AZ, Arribere J. 2018. A Small RNA Isolation and Sequencing Protocol and Its Application to Assay CRISPR RNA Biogenesis in Bacteria. Bio Protoc.8(4). Epub 2018/03/31. doi: 10.21769/BioProtoc.2727. PubMed PMID: 29600253; PubMed Central PMCID: PMC5870890.
- Vaughen J, Igaki T. Breaking Down Neighbors to Fuel Tumorigenesis. Developmental cell. 2017;40(3):219-220. doi: 10.1016/j.devcel.2017.01.011. PubMed PMID: 28171745. PMCID: PMC6207202.
- Vaughen J, Igaki T. Slit-Robo Repulsive Signaling Extrudes Tumorigenic Cells from Epithelia. Developmental cell. 2016 December 19;39(6):683-695. PubMed PMID: 27997825; PubMed Central PMCID: PMC6207184.
- Wenderski W, Maze I. Histone turnover and chromatin accessibility: critical mediators of neurological development, plasticity, and disease. BioEssays : news and reviews in molecular, cellular and developmental biology. 2016;38(5):410-9. doi: 10.1002/bies.201500171. PubMed PMID: 26990528; PubMed Central PMCID: PMC4968875.
- Alcantara D, Timms AE, Gripp K, Baker L, Park K, Collins S, Cheng C, Stewart F, Mehta SG, Saggar A, Sztriha L, Zombor M, Caluseriu O, Mesterman R, Van Allen MI, Jacquinet A, Ygberg S, Bernstein JA, Wenger AM, Guturu H, Bejerano G, Gomez-Ospina N, Lehman A, Alfei E, Pantaleoni C, Conti V, Guerrini R, Moog U, Graham JM, Jr., Hevner R, Dobyns WB, O'Driscoll M, Mirzaa GM. Mutations of AKT3 are associated with a wide spectrum of developmental disorders including extreme megalencephaly. Brain : a journal of neurology. 2017;140(10):2610-22. doi: 10.1093/brain/awx203. PubMed PMID: 28969385. PMCID: PMC6080423
- Byers JS, Jarosz DF. High-throughput Screening for Protein-based Inheritance in S. cerevisiae. Journal of visualized experiments : JoVE. 2017(126). doi: 10.3791/56069. PubMed PMID: 28809826. PMC5614125.
- Chang ACY, Chang ACH, Kirillova A, Sasagawa K, Su W, Weber G, Lin J, Termglinchan V, Karakikes I, Seeger T, Dainis AM, Hinson JT, Seidman J, Seidman CE, Day JW, Ashley E, Wu JC, Blau HM. 2018. Telomere shortening is a hallmark of genetic cardiomyopathies. Proc Natl Acad Sci U S A.115(37):9276-81. Epub 2018/08/29. doi: 10.1073/pnas.1714538115. PubMed PMID: 30150400. PMCID: PMC6140486
- Chang AH, Raftrey BC, D'Amato G, Surya VN, Poduri A, Chen HI, Goldstone AB, Woo J, Fuller GG, Dunn AR, Red-Horse K. DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12-CXCR4 signaling axis. Genes & development. 2017. doi: 10.1101/gad.301549.117. PMID: 28779009; PMCID: PMC5580653. Free PMC Article
- Cheng MH, Andrejka L, Vorster PJ, Hinman A, Lipsick JS. The Drosophila LIN54 homolog Mip120 controls two aspects of oogenesis. Biology open. 2017;6(7):967-78. doi: 10.1242/bio.025825. PubMed PMID: 28522430; PubMed Central PMCID: PMC5550918.
- Cheng MH, Andrejka L, Vorster PJ, Hinman A, Lipsick JS. The Drosophila LIN54 homolog Mip120 controls two aspects of oogenesis. Biol Open. 2017 Jul 15;6(7):967-978. doi: 10.1242/bio.025825. PMC5550918.
- Costa HA, Neal JW, Bustamante CD, Zehnder JL. Identification of a Novel Somatic Mutation Leading to Allele Dropout for EGFR L858R Genotyping in Non-Small Cell Lung Cancer. Mol Diagn Ther. 2017 Aug;21(4):431-436. doi: 10.1007/s40291-017-0275-y. PMCID: PMC5511778.
- Fu BX, Wainberg M, Kundaje A, Fire AZ. High-Throughput Characterization of Cascade type I-E CRISPR Guide Efficacy Reveals Unexpected PAM Diversity and Target Sequence Preferences. Genetics. 2017 Aug;206(4):1727-1738. doi: 10.1534/genetics.117.202580. Epub 2017 Jun 20. PMCID: PMC5560783.
- Hess GT, Frésard L, Han K, Lee CH, Li A, Cimprich KA, Montgomery SB, Bassik MC. Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells. Nat Methods. 2016 Dec;13(12):1036-1042. doi: 10.1038/nmeth.4038. Epub 2016 Oct 31. PubMed PMID: 27798611; PMCID: PMC5557288.
- Hilton HG, McMurtrey CP, Han AS, Djaoud Z, Guethlein LA, Blokhuis JH, Pugh JL, Goyos A, Horowitz A, Buchli R, Jackson KW, Bardet W, Bushnell DA, Robinson PJ, Mendoza JL, Birnbaum ME, Nielsen M, Garcia KC, Hildebrand WH, Parham P. The Intergenic Recombinant HLA-B∗46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands. Cell Rep. 2017 May 16;19(7):1394-1405. doi: 10.1016/j.celrep.2017.04.059 PMCID: PMC5510751.
- Ho ATV, Palla AR, Blake MR, Yucel ND, Wang YX, Magnusson KEG, Holbrook CA, Kraft PE, Delp SL, Blau HM. Prostaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strength. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6675-6684. doi: 10.1073/pnas.1705420114. Epub 2017 Jun 12. PMCID: PMC5495271.
- Schrader JM, Li GW, Childers WS, Perez AM, Weissman JS, Shapiro L, McAdams HH. Dynamic translation regulation in Caulobacter cell cycle control. Proceedings of the National Academy of Sciences of the United States of America. 2016;113(44):E6859-E67. doi: 10.1073/pnas.1614795113. PubMed PMID: 27791168; PubMed Central PMCID: PMC5098616.Hsu J, Sage J. Novel functions for the transcription factor E2F4 in development and disease. Cell Cycle. 2016 Dec;15(23):3183-3190. Epub 2016 Oct 18. PMCID: PMC5176148.
- Tanner EJ, Kirkegaard KA, Weinberger LS. Exploiting Genetic Interference for Antiviral Therapy. PLoS genetics. 2016;12(5):e1005986. doi: 10.1371/journal.pgen.1005986. PubMed PMID: 27149616; PubMed Central PMCID: PMC4858160.
- Kadoch C, Williams RT, Calarco JP, Miller EL, Weber CM, Braun SM, Pulice JL, Chory EJ, Crabtree GR. Dynamics of BAF-Polycomb complex opposition on heterochromatin in normal and oncogenic states. Nat Genet. 2017 Feb;49(2):213-222. doi: 10.1038/ng.3734. Epub 2016 Dec 12. PMCID: PMC5285326.
- Martin AR, Gignoux CR, Walters RK, Wojcik GL, Neale BM, Gravel S, Daly MJ, Bustamante CD, Kenny EE. Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations. Am J Hum Genet. 2017 Apr 6;100(4):635-649. doi: 10.1016/j.ajhg.2017.03.004. Epub 2017 Mar 30 PMCID: PMC5384097.
- Miller EL, Hargreaves DC, Kadoch C, Chang CY, Calarco JP, Hodges C, Buenrostro JD, Cui K, Greenleaf WJ, Zhao K, Crabtree GR. TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin. Nat Struct Mol Biol. 2017 Apr;24(4):344-352. doi: 10.1038/nsmb.3384. Epub 2017 Feb 27. PMCID: PMC5395302.
- Morgens DW, Wainberg M, Boyle EA, Ursu O, Araya CL, Tsui CK, Haney MS, Hess GT, Han K, Jeng EE, Li A, Snyder MP, Greenleaf WJ, Kundaje A, Bassik MC. Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens. Nat Commun. 2017 May 5;8:15178. doi: 10.1038/ncomms15178. PMCID: PMC5424143.
- Perez AM, Mann TH, Lasker K, Ahrens DG, Eckart MR, Shapiro L. A Localized Complex of Two Protein Oligomers Controls the Orientation of Cell Polarity. MBio. 2017 Feb 28;8(1). pii: e02238-16. doi: 10.1128/mBio.02238-16. 28246363; PMC5347347.
- San Martín Á, Rodriguez-Aliaga P, Molina JA, Martin A, Bustamante C, Baez M. Knots can impair protein degradation by ATP-dependent proteases. Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):9864-9869. doi: 10.1073/pnas.1705916114. Epub 2017 Aug 28. PMCID: PMC5604015.
- Saurabh S, Perez AM, Comerci CJ, Shapiro L, Moerner WE. Super-Resolution Microscopy and Single-Protein Tracking in Live Bacteria Using a Genetically Encoded, Photostable Fluoromodule. Curr Protoc Cell Biol. 2017 Jun 19;75:4.32.1-4.32.22. doi: 10.1002/cpcb.21. PMID: 28627757 PMC5768428
- Silas S, Makarova KS, Shmakov S, Páez-Espino D, Mohr G, Liu Y, Davison M, Roux S, Krishnamurthy SR, Fu BXH, Hansen LL, Wang D, Sullivan MB, Millard A, Clokie MR, Bhaya D, Lambowitz AM, Kyrpides NC, Koonin EV, Fire AZ. On the Origin of Reverse Transcriptase-Using CRISPR-Cas Systems and Their Hyperdiverse, Enigmatic Spacer Repertoires. MBio. 2017 Jul 11;8(4). pii: e00897-17. doi: 10.1128/mBio.00897-17 PMCID: PMC5513706.
- Wroblewski EE, Guethlein LA, Norman PJ, Li Y, Shaw CM, Han AS, Ndjango JN, Ahuka-Mundeke S, Georgiev AV, Peeters M, Hahn BH, Parham P. Bonobos Maintain Immune System Diversity with Three Functional Types of MHC-B. J Immunol. 2017 May 1;198(9):3480-3493. doi: 10.4049/jimmunol.1601955. Epub 2017 Mar 27. PMCID: PMC5469624.
- Bayless NL, Greenberg RS, Swigut T, Wysocka J, Blish CA. Zika Virus Infection Induces Cranial Neural Crest Cells to Produce Cytokines at Levels Detrimental for Neurogenesis. Cell Host Microbe. 2016 Oct 12;20(4):423-428. doi: 10.1016/j.chom.2016.09.006. Epub 2016 Sep 29. PMCID: PMC5113290.
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