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GCRC

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Programs

The eight major programs and investigators which form the core of the GCRC are as follows:

  1. Recombinant Idiotype Vaccines for the Immunotherapy of Follicular Non-Hodgkin's Lymphomas (R. Levy),
  2. Clinical Trials in HIV Positive Patients (T. Merigan),
  3. Surgery for Necrotizing Enterocolitis in Human Infants (L. Moss),
  4. Studies of Hypothalamic-Pituitary-Adrenal Axis in Psychotic Depression (A. Schatzberg),
  5. A Phase I Study of ZD1839 (Iressa) in Combination with Oxaliplatin, 5-Fluorouracil, and Leucovorin in Advanced Solid Malignancies (B. Sikic),
  6. Clinical Experiment of H-Pylori Transmission (J. Parsonnet),
  7. Pathophysiology of Hepatorenal Syndrome (B. Myers) and
  8. Gene Therapy for Hemophilia (M. Kay and B. Glader).

Other current projects include:

  • Coronary Heart Disease Risk Factors in Patients with Noninsulin Dependent Diabetes
  • Genetic Determinants of Human Hypertension
  • HPA Axis/Dopamine Interactions in Psychotic Depression
  • Influence of Dietary Intervention on Survival of Women with Breast Cancer
  • Transcranial Doppler Monitoring of Microemboli in Patients with Mechanical Heart Valve Replacements
  • Radioimmunotherapy of Cancers
  • Prevention of Type I Diabetes, and
  • Effects of Smoking Cessation on Vascular Reactivity