Publications

Peer-Reviewed Original Articles

  • Schuck R, Flores R, Fung LK. Sex/Gender Differences in Symptomology and Camouflaging in Adults with Autism Spectrum Disorder. Journal of Autism & Developmental Disabilities. Published on line April 3 2019 (https://doi.org/10.1007/s10803-019-03998-y).
  • Parker KJ, Oztan O, Libove RA, Mohsin N, Karhson DS, Sumiyoshi RD, Summers JE, Hinman KE, Motonaga KS, Phillips JM, Carson DS, Fung LK, Garner JP, Hardan AY. A Randomized Controlled Pilot Trial of Intranasal Vasopressin Treatment for Social Deficits in Children with Autism. Science Translational Medicine. In press.
  • Palner M, Beinat C, Banister S, Zanderigo F, Park J, Shen B, Hjoernevik T, Fung L, Chin FT. Effects of common anesthetic agents on [18F]flumazenil binding to the GABAA receptor. European Journal of Nuclear Medicine and Molecular Imaging Research. 2016 Dec;6(1):80. PMID: 27826950.
  • Fung LK, Mahajan R, Nozzolillo A, Bernal P, Krasner A, Jo B, Coury D, Whitaker A, Veenstra-Vanderweele J, Hardan AY. Pharmacologic treatment of severe irritability and problem behaviors in autism: a systematic review and meta-analysis. Pediatrics. 137(s2) February 2016:e20152851. PMID: 26908468.
  • Hardan AY, Fung LK, Frazier T, Berquist SW, Minshew NJ, Keshavan MS, Stanley JA. A proton spectroscopy study of white matter in children with autism. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2015 Nov 16;66:48-53. PMID: 26593330.
  • Fung LK, Akil M, Widge A, Roberts LW, Etkin A. Attitudes towards neuroscience education in psychiatry: a national multi-stakeholder survey. Academic Psychiatry. 2015 Apr;39(2):139-46. PMID: 25001432.
  • Fung LK, Libove R, Phillips J, Haddad F, Hardan AY. Brief Report: An open-label study of the neurosteroid pregnenolone in adults with autism spectrum disorder. Journal of Autism & Developmental Disabilities. 2014 Nov;44(11):2971-7. PMID: 24849255.
  • Fung LK, Akil M, Widge A, Roberts LW, Etkin A. Attitudes toward neuroscience education among psychiatry residents and fellows. Academic Psychiatry. 2014 Apr;38(2):127-34. PMID: 24493359.
  • Fung LK, Chahal L, Libove R, Bivas R, Hardan AY.  A retrospective review of the effectiveness of aripiprazole in the treatment of sensory abnormalities in autism. Journal of Child and Adolescent Psychopharmacology. 2012 Jun;22(3):245-8. PMID: 22537360.
  • Hardan AY, Fung LK, Libove R, Obukhanych TV, Nair S, Herzenberg LA, Frazier TW, Tirouvanziam R.  A randomized, placebo-controlled, double-blind trial of N-Acetylcysteine in children with autism. Biological Psychiatry. 2012 Jun 1;71(11):956-61. PMID: 22342106.
  • Hodgetts KJ, Ge P, Yoon T, Lombaert SD, Brodbeck R, Gulianello M, Kieltyka A, Horvath RF, Kehne JH, Krause JE, Maynard GD, Hoffman D, Lee Y, Fung L, Doller D. Discovery of N-(1-Ethylpropyl)-[3-methoxy-5-(2-methoxy-4-trifluoromethoxyphenyl)-6-methyl-pyrazin-2-yl]amine 59 (NGD 98-2): An Orally Active Corticotropin Releasing Factor-1 (CRF-1) Receptor Antagonist. Journal of Medicinal Chemistry. 2011 Jun 23;54(12):4187-4206. PMID: 21618986.
  • Hardan AY, Fung LK, Amin H. Risperidone: Switching from brand-name to generic. Journal of Child and Adolescent Psychopharmacology 2010. 20(5):457-458. PMID: 20973719.
  • Vrudhula VM, Dasgupta B, Pin SS, Burris KD, Balanda LA, Fung LK, Fiedler T, Browman KE, Taber MT, Zhang J, Macor JE, Dubowchik GM. Design, synthesis and evaluation of constrained tetrahydroimidazopyrimidine derivatives as antagonists of corticotropin-releasing factor type 1 receptor (CRF1R). Bioorganic and Medicinal Chemistry Letters. 2010 Mar 15;20(6):1905-9. PMID: 20185312.
  • Mattai A, Fung L, Bakalar J, Overman G, Tossell J, Miller R, Rapoport J, Gogtay N. Adjunctive use of lithium carbonate for the management of neutropenia in clozapine-treated children. Human Psychopharmacology. 2009 Oct; 24(7):584-9. PMID: 19743394.
  • Blum CA, Zheng X, Brielmann H, Hodgetts KJ, Bakthavatchalam R, Chandrasekhar J, Krause JE, Cortright D, Matson D, Crandall M, Ngo CK, Fung L, Day M, Kershaw M, De Lombaert S, Chenard BL. Aminoquinazolines as TRPV1 antagonists: modulation of drug-like properties through the exploration of 2-position substitution. Bioorganic and Medicinal Chemistry Letters. 2008 Aug 15;18(16):4573-7. PMID: 18662872.
  • Han X, Pin SS, Burris K, Fung LK, Huang S, Taber MT, Zhang J, Dubowchik GM. Synthesis and structure-activity relationship of imidazo[1,2-]benzimidazoles as corticotropin-releasing factor 1 receptor antagonists. Bioorganic and Medicinal Chemistry Letters. 2005 Sep; 15(18): 4029-4032. PMID: 15990298.
  • Han X, Michne JA, Pin SS, Burris K, Balanda LA, Fung LK, Fiedler T, Browman KE, Taber MT, Zhang J, Dubowchik GM. Synthesis, structure-activity relationships, and anxiolytic activity of 7-aryl-6,7-dihydroimidazoimidazole corticotropin-releasing factor 1 receptor antagonists. Bioorganic and Medicinal Chemistry Letters. 2005 Sep; 15(17): 3870-3873. PMID: 15982881.
  • Dubowchik GM, Michne JA, Zuev D, Schwartz W, Scola PM, James CA, Ruediger EH, Pin SS, Burris KD, Balanda LA, Gao Q, Wu D, Fung L, Fiedler T, Browman KE, Taber MT, Zhang J. 2-arylaminothiazoles as high-affinity corticotropin-releasing factor 1 receptor (CRF1R) antagonists: synthesis, binding studies and behavioral efficacy. Bioorganic and Medicinal Chemistry Letters. 2003 Nov; 13(22): 3997-4000. PMID: 14592493.
  • Fura A, Harper TW, Zhang H, Fung L, Shyu WC. Shift in pH of biological fluids during storage and processing: effect on bioanalysis. Journal of Pharmaceutical and Biomedical Analysis. 2003 Jul; 32(3): 513-522. PMID: 14565556.
  • Fung LK, Ewend MG, Sills A, Sipos EP, Thompson R, Watts M, Colvin OM, Brem H, Saltzman WM. Pharmacokinetics of interstitial delivery of carmustine, 4-hydroperoxycyclophosphamide, and paclitaxel from a biodegradable polymer implant in the monkey brain. Cancer Research. 1998 Feb; 58(4): 672-684. PMID: 9485020.
  • Fung LK, Shin M, Tyler B, Brem H, Saltzman WM. Chemotherapeutic drugs released from polymers: distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea in the rat brain. Pharmaceutical Research. 1996 May; 13(5): 671-678. PMID: 8860421.
  • Strasser JF, Fung LK, Eller S, Grossman SA, Saltzman WM. Distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea and tracers in the rabbit brain after interstitial delivery by biodegradable polymer implants. Journal of Pharmacology and Experimental Therapeutics. 1995 Dec; 275(3): 1647-1655. PMID: 8531140.

Other Peer-reviewed Articles

  • Fung LK and Reiss AL. Moving towards integrative, multi-dimensional research in modern psychiatry: lessons learned from fragile X syndrome. Biological Psychiatry. 2016 Jul 15;80(2):100-11. PMID: 26868443.
  • McGuire K, Fung LK, Hagopian L, Vasa RA, Mahajan R, Bernal P, Silberman AE, Wolfe A, Coury D, Veenstra-Vanderweele J, Hardan AY, Whitaker A. Irritability and problem behavior in autism spectrum disorder: a practice pathway for pediatric primary care. Pediatrics. 137(S2), February 2016:e20152851. PMID: 26908469.
  • Fung LK and Hardan AY. Developing medications targeting glutamatergic dysfunction in autism: progress to date. CNS Drugs. 2015 Jun; 29(6):453-63. PMID: 26104862.
  • Fung LK and Hardan AY. Autism and DSM-5: implications to patients, families, clinicians, and researchers. Journal of Asian Psychiatry. 2014 Oct;11:93-7. PMID: 25219947.
  • Fung LK, Quintin E, Haas BW, and Reiss AL. Conceptualizing neurodevelopmental disorders through a mechanistic understanding of fragile X syndrome and Williams syndrome. Current Opinion in Neurology. 2012 Apr; 25(2): 112–124. PMID: 22395002. [LKF is awarded the Miller Award for writing this paper.]
  • Fung LK, Saltzman WM. Polymeric implants for cancer chemotherapy. Advanced Drug Delivery Reviews. 1997 Jul; 26(2-3): 209-230. PMID: 10837544.
  • Mak M, Fung L, Strasser JF, Saltzman WM. Distribution of drugs following controlled delivery to the brain interstitium. Journal of Neuro-Oncology. 1995 Nov; 26(2): 91-102. PMID: 8787851.

Editorial

  • Fung LK. One step closer to shining light in humans? Science Translational Medicine. 23 Mar 2016: Vol. 8, Issue 331, pp. 331ec48.
  • Fung LK. New neural measures signal autism. Science Translational Medicine. 04 May 2016: Vol. 8, Issue 337, pp. 337ec73.
  • Fung LK. Does a mother’s voice influence a child’s social communication abilities? Science Translational Medicine. 15 Jun 2016: Vol. 8, Issue 343, pp. 343ec95.
  • Fung LK. A sneak peek at personalized medicine in autism? Science Translational Medicine. 27 Jul 2016: Vol. 8, Issue 349, pp. 349ec119.
  • Fung LK. Can imaging predict future suicidal behavior? Science Translational Medicine. 7 Sep 2016: Vol. 8, Issue 355, pp. 355ec143.
  • Fung LK. New genetic insights into brain size. Science Translational Medicine. 19 Oct 2016: Vol. 8, Issue 361, pp. 361ec166.
  • Fung LK. Imaging serotonin reuptake in the living brain. Science Translational Medicine. 30 Nov 2016: Vol. 8, Issue 367, pp. 367ec191. PMID: 27903859
  • Fung LK. A sterile animal model for neuroinflammation? Science Translational Medicine. 18 Jan 2017: Vol. 9, Issue 373, DOI: 10.1126/scitranslmed.aal4994. PMID: 28100836

Non-Peer Reviewed Journal Articles

  • Froehlich W and Fung LK. Autism spectrum and neurodevelopmental disorders: clinical update for psychiatrists. Psychiatric Times. 2012 Dec; 29(11).

Book Chapters

  • Fung LK and Reiss AL. Chapter 8. Genetic disorders associated with the autism spectrum disorder phenotype. In McDougle C: Primer on Autism Spectrum Disorder. (2016) Oxford University Press, New York, NY.
  • Fung LK and Hardan AY. Corpus Callosum and Autism. In Casanova M: Autism Imaging and Devices. CRC Press, Boca Raton, FL. In press.
  • Fung LK and Hardan AY. Chapter II.4. Oxidative Stress and the Role of N-acetylcysteine in Psychiatric Disorders. In Frye R and Berk M: The Therapeutic Use of NAC in Medicine. Adis Publications, Springer Healthcare, Auckland, New Zealand. In press.
  • Fung LK. Chapter 19. Autism Spectrum Disorder. In Roberts LW: University Student Mental Health: A Guide for Psychiatrists, Psychologists, and Leaders Serving Higher Education. American Psychiatric Association Publishing, Arlington, VA. In press.
  • Hong DS, Fung LK and Hardan AY. Chapter 9. Neurodevelopmental Disorders. In Roberts LW: American Psychiatric Association Publishing Textbook of Psychiatry. Seventh Edition. American Psychiatric Association Publishing, Arlington, VA. In press.

Thesis and Dissertation

  • Fung LK (1996). Theoretical and Experimental Pharmacokinetics of Polymer Delivery of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in a Rat Brain Model. Master’s thesis, Johns Hopkins University, Baltimore, MD.
  • Fung LK (1998). Pharmacokinetics and Pharmacodynamics of Chemotherapeutic Agents Released from Biodegradable Polymers in the Brain. PhD dissertation, Cornell University, Ithaca, NY.