PUBLICATIONS

2017

Vision science and adaptive optics, the state of the field

Marcos, S, Werner, JS, Burns, SA, Merigan, WH, Artal, P, Atchison, DA, Hampson, KM, Legras, R, Lundstrom, L, Yoon, G, Carroll, J, Choi, SS, Doble, N, Dubis, AM, Dubra, A, Elsner, A, Jonnal, R, Miller, DT, Paques, M, Smithson, HE, Young, LK, Zhang, Y, Campbell, M, Hunter, J, Metha, A, Palczewska, G, Schallek, J, Sincich, LC.
Vision Research, Epub ahead of print (2017).

[PubMed] [Journal]

Repeatability and longitudinal assessment of foveal cone structure in CNGB3-associated achromatopsia

Langlo, CS, Erker, LR, Parker, M, Patterson, EJ, Higgins, BP, Summerfelt, P, Razeen, MM, Collison, FT, Fishman, GA, Kay, CN, Zhang, J, Weleber, RG, Yang, P, Pennesi, ME, Lam, BL, Chulay, JD, Dubra, A, Hauswirth, WW, Wilson, DJ, Carroll, J; ACHM-001 study group.
Retina, Epub ahead of print (2017).

[PubMed] [Journal]

2016

In vivo imaging of the human retinal pigment epithelial mosaic using adaptive optics enhanced indocyanine green ophthalmoscopy

Tam, J, Liu, J, Dubra, A, Fariss, R.
Investigative Ophthalmology & Visual Science, 57(10):4376-84 (2016).

[Pubmed] [Journal]

Multimodal imaging of photoreceptor structure in choroideremia

Sun, LW, Johnson, RD, Williams, V, Summerfelt, P, Dubra, A, Weinberg, DV, Stepien, KE, Fishman, GA, Carroll, J.
PLOS ONE 11(12): e0167526 (2016).

[PubMed] [Journal]

Residual foveal cone structure in CNGB3-associated achromatopsia

Langlo, CS, Patterson, EJ, Higgins, BP, Summerfelt, P, Razeen, MM, Erker, LR, Parker, M, Collison, FT, Fishman, GA, Kay, CN, Zhang, J, Weleber, RG, Yang, P, Wilson, DJ, Pennesi, ME, Lam, BL, Chiang, J, Chulay, JD, Dubra, A, Hauswirth, WW, Carroll, J, ACHM-001 Study Group. 
Investigative Ophthalmology & Visual Science, 57: 3984-3995 (2016).

[PubMed] [Journal]

Photoreceptor inner segment morphology in best vitelliform macular dystrophy

Scoles, D, Sulai, YN, Cooper, RF, Higgins, BP, Johnson, RD, Carroll, J, Dubra, A, Stepien, KE.
Retina, Epub ahead of print (2016).

[PubMed] [Journal]

Cone photoreceptor structure in patients with X-linked cone dysfunction and red-green color vision deficiency

Patterson, EJ, Wilk, M, Langlo, CS, Kasilian, M, Ring, M, Hufnagel, RB, Dubis, AM, Tee, JJ, Kalitzeos, A, Gardner, JC, Ahmed, ZM, Sisk, RA, Larsen, M, Sjoberg, S, Connor, TB, Dubra, A, Neitz, J, Hardcastle, AJ, Neitz, M, Michaelides, M, Carroll, J.
Investigative Ophthalmology & Visual Science, 57(8): 3853-3863 (2016).

[PubMed] [Journal]

Imaging foveal microvasculature: optical coherence tomography angiography versus adaptive optics scanning light ophthalmoscope fluorescein angiography

Mo, S, Krawitz, B, Efstathiadis, E, Geyman, L, Weitz, R, Chui, TY, Carroll, J, Dubra, A, Rosen, RB.
Investigative Ophthalmology & Visual Science, 57(9): OCT130-140 (2016).

[PubMed] [Journal]

Assessing the spatial relationship between fixation and foveal specializations

Wilk, MA, Dubis, AM, Cooper, RF, Summerfelt, P, Dubra, A, Carroll, J.
Vision Research, Epub ahead of print (2016).

[PubMed] [Journal]

Longitudinal imaging of microvascular remodelling in proliferative diabetic retinopathy using adaptive optics scanning light ophthalmoscopy

Chui, TY, Pinhas, A, Gan, A, Razeen, M, Shah, N, Cheang, E, Liu, CL, Dubra, A, Rosen, RB.
Ophthalmic & Physiological Optics, 36(3): 290-302 (2016).

[PubMed] [Journal]

Automatic detection of cone photoreceptors in split detector adaptive optics scanning light ophthalmoscope images

Cunefare, D, Cooper, RF, Higgins, B, Katz, DF, Dubra, A, Carroll, J, Farsiu, S.
Biomedical Optics Express, 7(5): 2036-2050 (2016).

[PubMed] [Journal]

Effects of intraframe distortion on measures of cone mosaic geometry from adaptive optics scanning light ophthalmoscopy

Cooper, RF, Sulai, YN, Dubis, AM, Chui, TY, Rosen, RB, Michaelides, M, Dubra, A, Carroll, J.
Translational Vision Science & Technology, 5(1): 10 eCollection (2016).

[PubMed] [Journal]

Correlating photoreceptor mosaic structure to clinical findings in Stargardt disease

Razeen, MM, Cooper, RF, Langlo, CS, Goldberg, MR, Wilk, MA, Han, DP, Connor, TB Jr, Fishman, GA, Collison, FT, Sulai, YN, Dubra, A, Carroll, J, Stepien, KE.
Translational Vision Science & Technology, 5(2): 6 eCollection (2016).

[PubMed] [Journal]

Assessing photoreceptor structure in retinitis pigmentosa and usher syndrome

Sun, LW, Johnson, RD, Langlo, CS, Cooper, RF, Razeen, MM, Russillo, MC, Dubra, A, Connor, TB Jr, Han, DP, Pennesi, ME, Kay, CN, Weinberg, DV, Stepien, KE, Carroll, J.
Investigative Ophthalmology & Visual Science, 57(6): 2428-2442 (2016).

[PubMed] [Journal]

Noninvasive imaging of the thirteen-lined ground squirrel photoreceptor mosaic

Sajdak, B, Sulai, YN, Langlo, CS, Luna, G, Fisher, SK, Merriman, DK, Dubra, A.
Visual Neuroscience, 33: E003 (2016).

[PubMed] [Journal]

Assessing photoreceptor structure associated with ellipsoid zone disruptions visualized with optical coherence tomography

Scoles, D, Flatter, JA, Cooper, RF, Langlo, CS, Robison, S, Neitz, M, Weinberg, DV, Pennesi, ME, Han, DP, Dubra, A, Carroll, J.  
Retina, 36(1): 91-103 (2016).

[PubMed] [Journal]

2015

Fellow eye changes in patients with nonischemic central retinal vein occlusion: assessment of perfused foveal microvascular density and identification of nonperfused capillaries

Pinhas, A, Dubow, M, Shah, N, Cheang, E, Liu, CL, Razeen, M, Gan, A, Weitz, R, Sulai, YN, Chui, TY, Dubra, A, Rosen, RB.
Retina, 35(10): 2028-2036 (2015).

[PubMed] [Journal]

Assessing photoreceptor structure after macular hole closure

Hansen, S, Batson, S, Weinlander, KM, Cooper, RF, Scoles, DH, Karth, PA, Weinberg, DV, Dubra, A, Kim, JE, Carroll, J, Wirostko, WJ.
Retinal Cases & Brief Reports, 9(1): 15-20 (2015).

[PubMed] [Journal]

Confocal adaptive optics imaging of peripapillary nerve fiber bundles: implications for glaucomatous damage seen on circumpapillary OCT scans

Hood, DC, Chen, MF, Lee, D, Epstein, B, Alhadeff, P, Rosen, RB, Ritch, R, Dubra, A, Chui, TY.
Translational Vision Science & Technology, 4(2):12 (2015). 

[Pubmed] [Journal]

Retinal architecture in R9AP- and RGS9-associated retinal dysfunction (bradyopsia)

Strauss, RW, Dubis, AM, Cooper, RF, Ba-Abbad, R, Moore, AT, Webster, AR, Dubra, A, Carroll, J, Michaelides, M.
American Journal of Ophthalmology, 160(6): 1269-1275 (2015).

[PubMed] [Journal]

Adaptive optics imaging of healthy and abnormal regions of retinal nerve fiber bundles of patients with glaucoma

Chen, MF, Chui, TY, Alhadeff, P, Rosen, RB, Ritch, R, Dubra, A, Hood, DC.
Investigative Ophthalmology & Visual Science, 56(1):674-81 (2015). 

[Pubmed] [Journal]

2014

Comparison of adaptive optics scanning light ophthalmoscopic fluorescein angiography and offset pinhole imaging

Chui, TY, Dubow, M, Pinhas, A, Shah, N, Gan, A, Weitz, R, Sulai, YN, Dubra, A, Rosen, RB.
Biomedical Optics Express, 5(4):1173-89 (2014).

[Pubmed] [Journal]

Non-common path aberration correction in an adaptive optics scanning ophthalmoscope

Sulai, YN, Dubra, A.
Biomedical Optics Express, 5(9):3059-73 (2014).

[Pubmed] [Journal]

 

Assessment of perfused foveal microvascular density and identification of nonperfused capillaries in healthy and vasculopathic eyes

Pinhas, A, Razeen, M, Dubow, M, Gan, A, Chui, TY, Shah, N, Mehta, M, Gentile, RC, Weitz, R, Walsh, J, Sulai, YN, Carroll, J, Dubra, A, Rosen, RB.  
Investigative Ophthalmology & Visual Science, 55(12): 8056-8066 (2014).

[PubMed] [Journal]

Genotype-dependent variability in residual cone structure in achromatopsia: towards developing metrics for assessing cone health 

Dubis, AM, Cooper, RF, Aboshiha, J, Langlo, C, Sundaram, V, Liu, B, Collison, F, Fishman, GA, Moore, AT, Webster, AR, Dubra, A, Carroll, J, Michaelides, M.
Investigative Ophthalmology & Visual Science, 55(11): 7303-7311 (2014).

[PubMed] [Journal]

A prospective longitudinal study of retinal structure and function in achromatopsia

Aboshiha, J, Dubis, AM, Cowing, J, Fahy, RT, Sundaram, V, Bainbridge, JW, Ali, RR, Dubra, A, Nardini, M, Webster, AR, Moore, AT, Rubin, GS, Carroll, J, Michaelides, M.
Investigative Ophthalmology & Visual Science, 55(9): 5733-5743 (2014).

[PubMed] [Journal]

Visualization of retinal vascular structure and perfusion with a nonconfocal adaptive optics scanning light ophthalmoscope

Sulai, YN, Scoles, D, Harvey, Z, Dubra, A.
Journal of the Optical Society of America, A, Optics, Image Science and Vision, 31(3):569-79 (2014). 

[Pubmed] [Journal]

In vivo imaging of human cone photoreceptor inner segments

Scoles, D, Sulai, YN, Langlo, CS, Fishman, GA, Curcio, CA, Carroll, J, Dubra, A.
Investigative Ophthalmology & Visual Science, 55(7): 4244-4251 (2014).

[PubMed] [Journal]

Microscopic inner retinal hyper-reflective phenotypes in retinal and neurologic disease

Scoles, D, Higgins, BP, Cooper, RF, Dubis, AM, Summerfelt, P, Weinberg, DV, Kim, JE, Stepien, KE, Carroll, J, Dubra, A.
Investigative Ophthalmology & Visual Science, 55(7): 4015-4029 (2014).

[PubMed] [Journal]

The reliability of parafoveal cone density measurements

Liu, BS, Tarima, S, Visotcky, A, Pechauer, A, Cooper, RF, Landsem, L, Wilk, MA, Godara, P, Makhijani, V, Sulai, YN, Syed, N, Yasumura, G, Garg, AK, Pennesi, ME, Lujan, BJ, Dubra, A, Duncan, JL, Carroll, J.
British Journal of Ophthalmology, 98(8): 1126-1131 (2014).

[PubMed] [Journal]

Relationship between foveal cone specialization and pit morphology in albinism

Wilk, MA, McAllister, JT, Cooper, RF, Dubis, AM, Patitucci, TN, Summerfelt, P, Anderson, JL, Stepien, KE, Costakos, DM, Connor, TB, Wirostko, WJ, Chiang, PW, Dubra, A, Curcio, CA, Brilliant, M, Summers, CG, Carroll, J.
Investigative Ophthalmology & Visual Science, 55(7): 4186-4198 (2014).

[PubMed] [Journal]

A lensing effect of inner retinal cysts on images of the photoreceptor mosaic

Langlo, CS, Flatter, JA, Dubra, A, Wirostko, WJ, Carroll, J.
Retina, 34(2): 421-422 (2014).

[PubMed] [Journal]

Classification of human retinal microaneurysms using adaptive optics scanning light ophthalmoscope fluorescein angiography

Dubow, M, Pinhas, A, Shah, N, Cooper, RF, Gan, A, Gentile, RC, Hendrix, VL, Sulai, YN, Carroll, J, Chui, TY, Walsh, J, Weitz, R, Dubra, A, Rosen, RB.
Investigative Ophthalmology & Visual Science, 55(3): 1299-1309 (2014).

[PubMed] [Journal]

Retinal structure and function in achromatopsia: implications for gene therapy

Sundaram, V, Wilde, C, Aboshiha, J, Cowing, J, Han, C, Langlo, CS, Chana, R, Davidson, AE, Sergouniotis, PI, Bainbridge, JW, Ali, RR, Dubra, A, Rubin, G, Webster, AR, Moore, AT, Nardini, M, Carroll, J, Michaelides, M.
Ophthalmology, 121(1): 234-245 (2014).

[PubMed] [Journal]

Outer retinal structure following closed globe blunt ocular trauma

Flatter, JA, Cooper, RF, Dubow, MJ, Pinhas, A, Singh, RS, Kapur, R, Shah, N, Walsh, RD, Hong, SH, Weinberg, DV, Stepien, KE, Wirostko, WJ, Robison, S, Dubra, A, Rosen, RB, Connor, TB, Carroll, J.
Retina, 34(10): 2133-2146, (2014).

[PubMed] [Journal]

2013

In vivo dark-field imaging of the retinal pigment epithelium cell mosaic

Scoles, D, Sulai, YN, Dubra, A.
Biomedical Optics Express, 4(9):1710-23 (2013). 

[Pubmed] [Journal

 

In vivo imaging of retinal pigment epithelium cells in age related macular degeneration

Rossi, EA, Rangel-Fonseca, P, Parkins, K, Fischer, W, Latchney, LR, Folwell, MA, Williams, DR, Dubra, A, Chung, MM.
Biomedical Optics Express, 4(11):2527-39 (2013). 

[Pubmed] [Journal]

Human cone visual pigment deletions spare sufficient photoreceptors to warrant gene therapy

Cideciyan, AV, Hufnagel, RB, Carroll, J, Sumaroka, A, Luo, X, Schwartz, SB, Dubra, A, Land, M, Michaelides, M, Gardner, JC, Hardcastle, AJ, Moore, AT, Sisk, RA, Ahmed, Z, Kohl, S, Wissinger, B, Jacobson, SG.
Human Gene Therapy, 24(12): 993-1006 (2013).

[PubMed] [Journal]

In vivo imaging of human retinal microvasculature using adaptive optics scanning light ophthalmoscope fluorescein angiography

Pinhas, A, Dubow, M, Shah, N, Chui, TY, Scoles, D, Sulai, YN, Weitz, R, Walsh, JB, Carroll, J, Dubra, A, Rosen, RB.
Biomedical Optics Express, 4(8): 1305-1317 (2013).

[PubMed] [Journal]

Automatic cone photoreceptor segmentation using graph theory and dynamic programming

Chiu, SJ, Lokhnygina, Y, Dubis, AM, Dubra, A, Carroll, J, Izatt, JA, Farsiu, S.
Biomedical Optics Express, 4(6): 924-937 (2013).

[PubMed] [Journal]

Adaptive optics retinal imaging - clinical opportunities and challenges

Carroll, J, Kay, DB, Scoles, D, Dubra, A, Lombardo, M.
Current Eye Research, 38(7): 709–721 (2013).

[PubMed] [Journal]

Automatic detection of modal spacing (Yellott's ring) in AOSLO images

Cooper, RF, Langlo, CS, Dubra, A, Carroll, J.
Ophthalmic and Physiological Optics, 33(4): 540-549 (2013).

[PubMed] [Journal]

Selective cone photoreceptor injury in acute macular neuroretinopathy

Hansen, SO, Cooper, RF, Dubra, A, Carroll, J, Weinberg, DV.
Retina, 33(8): 1650-1658 (2013).

[PubMed] [Journal]

 

Outer retinal structure in Best vitelliform macular dystrophy

Kay, DB, Land, ME, Cooper, RF, Dubis, AM, Godara, P, Dubra, A, Carroll, J, Stepien, KE.
JAMA Ophthalmology, 131(9): 1207-1215 (2013).

[PubMed] [Journal]

2012

Adaptive optics retinal imaging in the living mouse eye

Geng, Y, Dubra, A, Yin, L, Merigan, WH, Sharma, R, Libby, RT, Williams, DR.
Biomedical Optics Express, 3(4):715-34 (2012). 

[Pubmed] [Journal]

Assessing retinal structure in complete congenital stationary night blindness and Oguchi disease

Godara, P, Cooper, RF, Sergouniotis, PI, Diederichs, MA, Streb, MR, Genead, MA, McAnany, JJ, Webster, AR, Moore, AT, Dubis, AM, Neitz, M, Dubra, A, Stone, EM, Fishman, GA, Han, DP, Michaelides, M, Carroll, J.
American Journal of Ophthalmology, 154(6):987-1001 (2012). 

[Pubmed] [Journal]

First-order design of a reflective viewfinder for adaptive optics ophthalmoscopy

Dubra, A, Sulai, YN.
Optics Express, 20(24):26596-605 (2012).

[Pubmed] [Journal]

Adaptive optics scanning ophthalmoscopy with annular pupils

Sulai, YN, Dubra, A.
Biomedical Optics Express, 3(7):1647-61(2012). 

[Pubmed] [Journal]

The effect of cone opsin mutations on retinal structure and the integrity of the photoreceptor mosaic

Carroll, J, Dubra, A, Gardner, JC, Mizrahi-Meissonnier, L, Cooper RF, Dubis, AM, Nordgren, R, Genead, M, Connor, TB Jr, Stepien, KE, Sharon, D, Hunt, DM, Banin, E, Hardcastle, AJ, Moore, AT, Williams, DR, Fishman, G, Neitz, J, Neitz, M, Michaelides, M.
Investigative Ophthalmology & Visual Science, 53(13): 8006-8015 (2012).

[PubMed] [Journal]

Repeatability of in vivo parafoveal cone density and spacing measurements

Garrioch, R, Langlo, C, Dubis, AM, Cooper, RF, Dubra, A, Carroll, J.
Optometry and Vision Science, 89(5): 632-643 (2012).

[PubMed] [Journal]

Relationship between the foveal avascular zone and foveal pit morphology

Dubis, AM, Hansen, BR, Cooper, RF, Beringer, J, Dubra, A, Carroll, J.
Investigative Ophthalmology & Visual Science, 53(3): 1628-1636 (2012).

[PubMed] [Journal]

Subclinical photoreceptor disruption in response to severe head trauma

Stepien, KE, Martinez, WM, Dubis, AM, Cooper, RF, Dubra, A, Carroll, J.
Archives of Ophthalmology, 130(3): 400-402 (2012).

[PubMed] [Journal]

2011

Retinal crystals in type 2 idiopathic macular telangiectasia 

Sallo, FB, Leung, I, Chung, M, Wolf-Schnurrbusch, UE, Dubra, A, Williams, DR, Clemons, T, Pauleikhoff, D, Bird, AC, Peto, T; MacTel Study Group.
Ophthalmology, 118(12):2461-7 (2011). 

[Pubmed] [Journal]

Optical properties of the mouse eye

Geng, Y, Schery, LA, Sharma, R, Dubra, A, Ahmad, K, Libby, RT, Williams, DR.
Biomedical Optics Express, 2(4):717-38 (2011). 

[Pubmed] [Journal]

Clinical applications of retinal imaging with adaptive optics

Carroll, J, Dubis, AM, Godara, P, Dubra, A, Stepien, KE.
US Ophthalmic Review, 4(2): 78-83 (2011).

[Journal]

 

Reflective afocal broadband adaptive optics scanning ophthalmoscope

Dubra, A, Sulai, Y.
Biomedical Optics Express, 2(6):1757-68 (2011). 

[Pubmed] [Journal

Spatial and temporal variation of rod photoreceptor reflectance in the human retina

Cooper, RF, Dubis, AM, Pavaskar, A, Rha, J, Dubra, A, Carroll, J.
Biomedical Optics Express, 2(9): 2577-2589 (2011).

[PubMed] [Journal]

Photoreceptor structure and function in patients with congenital achromatopsia

Genead, MA, Fishman, GA, Rha, J, Dubis, AM, Bonci, DM, Dubra, A, Stone, EM, Neitz, M, Carroll, J.
Investigative Ophthalmology & Visual Science, 52(10): 7298-7308 (2011).

[PubMed] [Journal]

Noninvasive imaging of the human rod photoreceptor mosaic using a confocal adaptive optics scanning ophthalmoscope

Dubra, A, Sulai, Y, Norris, JL, Cooper, RF, Dubis, AM, Williams, DR, Carroll, J.
Biomedical Optics Express, 2(7): 1864-1876 (2011).

[PubMed] [Journal]

Variability in parafoveal cone mosaic in normal trichromatic individuals

Dees, EW, Dubra, A, Baraas, RC.
Biomedical Optics Express, 2(5): 1351-1358 (2011).

[PubMed] [Journal]

Race- and sex-related differences in retinal thickness and foveal pit morphology

Wagner-Schuman, M, Dubis, AM, Nordgren, RN, Lei, Y, Odell, D, Chiao, H, Weh, E, Fischer, W, Sulai, Y, Dubra, A, Carroll, J.
Investigative Ophthalmology & Visual Science, 52(1): 625-634 (2011).

[PubMed] [Journal]

Images of photoreceptors in living primate eyes using adaptive optics two-photon ophthalmoscopy

Hunter, JJ, Masella, B, Dubra, A, Sharma, R, Yin, L, Merigan, WH, Palczewska, G, Palczewski, K, Williams, DR.
Biomedical Optics Express, 2(1):139-48 (2011).

[Pubmed] [Journal]

2009

In vivo imaging of microscopic structures in the rat retina

Geng, Y, Greenberg, KP, Wolfe, R, Gray, DC, Hunter, JJ, Dubra, A, Flannery, JG, Williams, DR, Porter, J.
Investigative Ophthalmology & Visual Science, 50(12):5872-9 (2009).

[Pubmed] [Journal]

In vivo autofluorescence imaging of the human and macaque retinal pigment epithelial cell mosaic

Morgan, J, Dubra, A, Wolfe, R, Merigan, WH, Williams, DR.
Investigative Ophthalmology & Visual Science, 50(3):1350-9 (2009).

[Pubmed] [Journal]