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November 24, 2020 City of Fremont Educational Webinar Night and Day: Sleep health reflects brain health. Register @ fsharifi@fremont.gov
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December 02, 2020 Women Faculty Networking Luncheon: Sara Singer Via Zoom (Link will be sent upon registration)
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December 02, 2020 Virtual Community Education Series Separating fad from fact: how to be savvy about "brain boosting" products by Dr. Quinn Kennedy. Register @ http://bit.ly/SVACVCES
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Eventful first year at new hospital
The 368-bed hospital building, which celebrates its one-year anniversary on Nov. 17, features technology and design features that have made handling COVID-19 cases easier.
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Disparities in COVID-19 hospitalizations
Researchers found that Black and Hispanic people made up 58% of all patients hospitalized for COVID-19 and 53% of those who died from the disease.
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Flu Crew helps prevent ‘twindemic’
This fall, medical and physician assistant students vaccinated thousands of people against the flu. The vaccinations could help prevent hospitals from being inundated with flu patients if COVID-19 cases surge.
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Diversity Week speakers address tough topics
Stanford Medicine community members remotely attended a weeklong series of talks, panels and workshops on reducing disparities and improving diversity in health care and medical education.
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How to bounce back from pandemic
Stanford Medicine experts have created a framework to guide public officials, school administrators and business leaders on re-establishing normal operations during and after the COVID-19 pandemic.
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Study finds infusion of young blood recharges brains of old mice
Wyss-Coray and his collaborators are working to discover the specific factors in the blood of young mice that can recharge the brain of an old mouse.
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Study finds gene variant puts women at higher risk of Alzheimer’s than it does men
Michael Greicius and his team have found that women who carry a copy of a gene variant called ApoE4 have a substantially greater risk of developing Alzheimer's.
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Study finds DNA of peanut-allergic kids changes with immune therapy
Research led by immunologist Kari Nadeau shows a blood test could determine whether patients who have been desensitized to their peanut allergies need to continue eating peanuts daily to retain their tolerance.
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A hydrogel process developed at Stanford creates transparent brain
Bioengineer Karl Deisseroth develops CLARITY, a process that renders brain tissue from mice transparent, allowing the entire brain structure and its wiring to be studied. -
A new technique induces egg growth in infertile women, and one gives birth
An in-vitro activation procedure developed by endocrinologist Aaron Hsueh is used to induce egg growth in some infertile women, and one gives birth.
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Michael Levitt, PhD, wins the Nobel Prize in Chemistry
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Thomas Südhof, MD, wins the Nobel Prize in Physiology or Medicine
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First-ever integrative 'omics' profile lets scientist discover, track his diabetes onset
Geneticist Michael Snyder integrates a deep analysis of his DNA, RNA and the proteins in his cells; the analysis correctly predicts that he will develop diabetes.
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Use of a single antibody caused human tumors transplanted into laboratory mice to disappeared or shrink
Pathologist Irving Weissman shows that a single antibody, which counters the effect of the CD47 molecule, shrinks a variety of human tumors transplanted into mice.
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New method allows sequencing of fetal genomes using maternal blood
Bioengineer Stephen Quake develops a groundbreaking method to sequence the genome of an unborn baby using only a blood sample from the mother.
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Brian Kobilka, MD, wins the Nobel Prize in Chemistry
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Lloyd B. Minor, MD, becomes Dean of the School of Medicine
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Using skin cells from patients with a severe genetic heart defect, researchers create human heart cells with the same genetic mutation, allowing them to test drugs on the cells
Using skin cells from patients with a severe genetic heart defect, neurobiologist Ricardo Dolmetsch creates human heart cells with the same genetic mutation, allowing his team to test drugs on the cells.
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Scientists demonstrate that elevating the brain's susceptibility to stimulation can produce social deficits resembling those of autism and schizophrenia
Bioengineer Karl Deisseroth uses the optogenetic technique in mice to switch on and off the social-behavior deficits that resemble those in humans with autism and schizophrenia.
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Stanford/Packard scientists find new uses for existing drugs by mining gene-activity data banks
Studies by Marina Sirota, Joel Dudley and Atul Butte demonstrate an approach that could quicken the pace of combating difficult diseases by matching them with drugs that are already approved for other indications.
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First use of aggregate patient data from electronic medical records to select treatment for a rare pediatric condition
Physicians at Lucile Packard Children's Hospital Stanford use aggregate patient data from electronic medical records to identify the best option for treating a patient with rare disorder.
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Scientists transform mouse skin cells directly into functional nerve cells with the application of just three genes
Pathologist Marius Wernig turns mouse skin cells into cells that insulate neurons with the application of just three genes.
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For the first time, researchers use a healthy person's complete genome sequence to predict his risk for dozens of diseases
A team of researchers analyzes bioengineer Stephen Quake's genome, predicting his likelihood of developing heart disease, Alzheimer's and cancer.
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Lorry I. Lokey Stem Cell Research Building opens
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Li Ka Shing Center for Learning and Knowledge opens
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Discovery of a "don't-eat-me" signal that allows blood cancer stem cells to migrate safely through the body
A team of researchers led by Irving Weissman discovers that leukemia stem cells evade detection by mimicking normal cells and moving safely within the body.
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Discovery of the first human bladder cancer stem cell
Pathologist Irving Weissman identifies the stem cell that gives rise to bladder cancer, and also shows how the cell uses the "don't-eat-me" signal, a molecule known as CD47, to evade the body's defenses.
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A researcher sequences his own genome for less than $50,000 and with a team of just two others
A technique developed by bioengineer Stephen Quake enables him to sequencs his own genome for less than $50,000 and with a team of just two others.
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Development of a test that reduces the risks in testing for chromosomal disorders such as Down syndrome
Bioenginner Stephen Quake and his team develop a method of screening a pregnant woman's blood to identify chromosomal disorders, such as Down syndrome, in her fetus.
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Ground breaking for the Lorry I. Lokey Stem Cell Research Building
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Ground breaking for Li Ka Shing Center for Learning and Knowledge
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Development of a new type of imaging system that can illuminate tumors in living subjects, getting pictures with a precision of nearly one-trillionth of a meter
Radiologist Sanjiv Gambhir develops a new type of imaging system that can illuminate tumors in living subjects with a precision of nearly one-trillionth of a meter
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Discovery of a molecule that kills kidney cancer cells
Radiation oncologist Amato Giaccia identifies a molecule that kills kidney cancer cells, which could provide new treatment options.
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Identification of a pattern of gene expression shared by transplant patients who are able to stay healthy without anti-rejection drugs
Pediatric nephrologist Minnie Sarwal finds that kidney transplant recipients with a similar gene-expression pattern were able to eliminate or reduce their dependence on immunosuppressive drugs.
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Application and expansion of optogenetics, a technique to control brain cell activity with light
Bioengineer Karl Deisseroth and his team develop a technique known as optogenetics that allows them to genetically alter brain cell activity in mice with light.
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Discovery that stem cells transplanted into the brains of rats and mice navigate toward areas damaged by stroke
Neurosurgeon Gary Steinberg tracks human stem cells transplated into brain of rats, finding that they successfully navigate toward areas damaged by stroke.
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Demolition of Fairchild Auditorium for new learning and knowledge center
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Andrew Fire, PhD, wins the Nobel Prize in Physiology or Medicine
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Roger Kornberg, PhD, wins the Nobel Prize in Chemistry
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Discovery of a protein that may explain why tumors in a low-oxygen environment are so deadly
Radiation oncologist Amato Giaccia identifies a protein called lysyl oxidase that, when found in a low-oxygen environment, may cause fast-spreading cancers.
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Discovery of obestatin, a hormone that suppresses appetite
Endocrinologist Aaron Hsueh discovers obestatin, a hormone that supresses appetite and may lead to treatments for obesity.
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Stanford Cancer Center opens
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The Clark Center (Bio-X) building and the underground parking garage on Pasteur Drive opens
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Discovery that Wnt genes, first discovered as critical genes in cancer, are also critical regulators of stem cell development
Developmental biologist Roeland Nusse isolates a group of proteins called Wnts that help keep stem cells in their youthful state.
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Discovery that training exercises can physically change the way the brain is wired
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Creation of the Stanford Institute for Cancer/Stem Cell Biology and Medicine, a multidisciplinary effort to develop novel treatments for cancer and other diseases
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First use of gene expression profiling to predict cancer outcomes
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First use of RNAi to switch off genes in mice
Geneticist Mark Kay uses a gene-therapy technique known as RNA inihibition to switch off genes in mice, which could point toward development treatments for cancer, hepatitis C and AIDS.
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Ground breaking for new cancer center
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Ground breaking and construction begins for new Clark Center (Bio-X) building
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Philip A. Pizzo, MD, becomes Dean of the School of Medicine
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Identification of a novel gene family involved in asthma
In a study in mice, researcher Rosemarie DeKruyff identifies a gene family that may underlie the development of asthma.
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Participation in the successful international effort to complete the human genome sequencing project
Teams headed by geneticist Richard Myers and biochemist Ronald Davis help sequence the human genome.
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Center for Clinical Sciences Research building opens
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First use of gene expression profiling to distinguish cancer sub-types
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Discovery of hereditary arthritis gene
Developmental biologist David Kingsley discovers that a gene that transports pyrophosphate into cells may regulate the development of arthritis in humans and animals.
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Solution of the structure of the RNA polymerase protein, a pivotal molecule that copies genes from DNA to RNA
Structural biologist Roger Kornberg shows the structure of the RNA polymerase protein, a step in the transfer of information from gene to protein. The discovery will later earn Kornberg the 2006 Nobel Prize in Chemistry.
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Stanford Hospital & Clinics and Lucile Packard Children’s Hospital returns to independent status ending a two-year merger with UCSF Medical Center
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Discovery of a genetic mutation that causes narcolepsy, a disabling sleep disorder affecting humans and animals
Sleep researcher Emmanuel Mignot identifies the defective gene that causes narcolepsy, a disabling sleep disorder affecting humans and animals.
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First experimental demonstration that limiting children’s television use prevents excess weight gain
Pediatrician Thomas Robinson finds that children who curtailed their television time gained significantly less body fat than those who didn't .
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Merger of the University of California-San Francisco Medical Center and UCSF/Mount Zion Medical Center with Stanford Hospital & Clinics and Lucile Packard Children’s Hospital to create UCSF Stanford Health Care, a private nonprofit organization
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Ground breaking for the new Center for Clinical Sciences Research
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Lucile Packard Children’s Hospital at Stanford board of directors transfers control of the facility to Stanford Health Services; Packard Children’s Hospital remains a separately licensed nonprofit corporation
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Completion of a multicenter trial showing that standard chemotherapy for most children with early-stage non-Hodgkin’s lymphoma can be safely reduced
Pediatric oncologist Michael Link leads a study that shows chemotherapy can be reduced by two-thirds in children with early-stage non-Hodgkin's lymphoma with no negative consequences.
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First optical imaging of gene expression in vivo
Christopher Contag develops a technique to detect light emitted when certain genes are activated in a living animal model.
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Discovery that mutations in a single gene are responsible for the most common form of skin cancer in humans
Developmental biologist Matthew Scott and a team at UC-San Francisco discover that a defect in the hedgehog gene causes basal cell carcinoma.
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Discovery that the p53 protein, known to be involved in controlling cancerous tumors, works as an “emergency brake” on cancer development
Oncologist Amato Giaccia and his colleagues find that the p53 protein, known to be involved in controlling cancerous tumors, can help halt cancer development.
Read more about Dr. Amato Giaccia (PDF)
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Eugene A. Bauer, MD, becomes Dean of the School of Medicine
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First optical imaging of infection in vivo
Christpher Contag and David Benaron develop optical imaging that allows researchers to detect and track bioluminescent bacteria in mice.
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Development of the microarray technology that allows researchers to see at once which genes of the thousands present in a cell are switched “on”
Biochemist Pat Brown and colleagues develop microarrays, or gene chips, that allow researchers to analyze the activity of thousands of genes in a cell at once.
Read more about Dr. Pat Brown (PDF)
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Creation of Stanford Health Services through the merger of Stanford University Hospital and Stanford University Clinic
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Development of the new diagnostic instrument for rapid bedside screening of hemolysis in jaundiced newborns
Neonatologist David Stevenson develops a diagnostic instrument that provides rapid bedside screening for the breakdown of red blood cells in jaundiced newborns.
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Development of a technique that enables researchers to toggle genes on and off in experimental animals
Pathologist Gerald Crabtree develops techniques that allow scientists to toggle genes on and off in animal models.
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First demonstration that lifestyle changes and drug therapy decrease heart attack rates and slows progression of atherosclerosis in coronary arteries
Researcher William Haskell shows that intensive lifestyle changes and prevention/treatment programs can reduce cardiac events and slow the progression of atherosclerosis in coronary arteries.
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First clinical trial testing methods for preventing eating disorders in adolescents
Researchers Joel Killen and Thomas Robinson publish findings that shed light on the causes of eating disorders in adolescents.
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Department of Psychiatry and Behavioral Sciences's new building on Quarry Road opens
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Stanford University Clinic's new outpatient building on Blake Wilbur Drive opens
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First functional image using time-resolved optics
Researchers produce the first functional image using time-resolved, near-infrared light.
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Stanford University Medical Center's new 780-space parking garage opens
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Richard M. Lucas Center for Magnetic Resonance Spectroscopy and Imaging opens
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Discovered the gene underlying a group of diseases called the demyelinating peripheral neuropathies in which the protective covering on nerves breaks down and the nerves are unable to function properly
Neurobiologist Eric Shooter finds a gene involved in nerve disorders in which the protective covering on nerves breaks down.
Read more about Dr. Shooter (PDF)
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Development of a genetically engineered vaccine to enhance patients’ immunological response against B-cell lymphoma
Oncologist Ron Levy develops a cancer vaccine that could prevent recurrrent lymphomas in patients treated with chemotherapy.
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Lucile Packard Children’s Hospital at Stanford opens
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Discovery of “off-switch” for genetic reproduction in bacteria
Biochemist Arthur Kornberg finds a chemical impulse that turns off the reproductive machinery in the chromosomes of E. coli bacteria.
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Beckman Center for Molecular and Genetic Medicine opens
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Stanford University Hospital opens new wing, the first major modernization project since 1959
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Discovery of the “homing receptor,” which guides white blood cells into the peripheral lymph nodes
Pathologist Eugene Butcher discovers a receptor that guides white blood cells into the peripheral lymph nodes.
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Development of an animal model for studying the human immune system
Researchers Irving Weissman and Mike McCune create an animal model that can be used to study a variety of human diseases.
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Ground breaking for the Lucile Packard Children’s Hospital at Stanford
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Isolation of pure hematopoietic stem cells from mice
Pathologist Irving Weissman isolates a rare mouse cell, known as the hematopoetic stem cell, which gives rise to all the cells of the blood and immune systems.
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Naming of the Center for Molecular and Genetic Medicine in honor of philanthropists Arnold and Mabel Beckman
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Remodel and modernization of Stanford University Clinic
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David Korn, MD, becomes Dean of the School of Medicine
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Isolation of a gene coding for part of the T-cell receptor, a key to the immune system’s function
Immunologist Mark Davis characterizes the T-cell receptor, believed to regulate the body's response to infectious agents and cancerous diseases.
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Renaming of outpatient clinics to Stanford University Clinic
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Development with UC-San Diego of the first human monoclonal antibody for treating septic shock
Stanford's Henry Kaplan and Nelson Teng and colleagues at UC-San Diego develop the first human monoclonal antibody for treating overwhelming infections.
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Dominick P. Purpura, MD, becomes Dean of the School of Medicine
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Stanford University Hospital embarks on a major modernization program to promote and expand facilities; signs agreement with Children’s Hospital at Stanford for consolidation of all pediatric services in the new Lucile Packard Children’s Hospital
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First report of successful use of monoclonal antibodies to treat cancer
Oncologist Ronald Levy reports the first successful use of monoclonal antibodies, which are laboratory-created molecules engineered to attach to specific defects in cancer cells.
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First successful human combined heart/lung transplant in the world (fourth attempted worldwide)
Mary Gohlke receives the world's first combined heart and lung transplant in a landmark operation led by surgeon Bruce Reitz.
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First creation of human hybridoma cell line
Henry Kaplan and Lennart Olsson create cells to manufacture human antibodies for the improved diagnosis and treatment of diseases.
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Paul Berg, PhD, wins the Nobel Prize in Chemistry
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Children’s Hospital at Stanford opens a new wing, consolidating all pediatric outpatient services of Stanford University Medical Center
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Discovery of dynorphin, a brain chemical 200 times more powerful than morphine
Pharmacologist Avram Goldstein discovers a chemical in the human brain that could lead to the development of powerful painkillers with fewer undesirable side effects.
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Discovery of link between exercise and increased “good” (HDL) cholesterol levels
John Farquhar and Peter Wood demonstrate that exercise is associated with an increase in "good" cholesterol levels, and can decrease the likelihood of coronary problems.
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