Fellows Research

  • Vazquez R, Vasquez Guillamet C, Rishi M, Florindez J, Dhawan P, Allen A, Manthous C, Lighthall G. Physical Examination in the Intensive Care Unit: Opinions of Physicians at Three Teaching Hospitals. Southwest J Pulmonary and Critical Care 2015; 10: 34-43.
  • Lighthall GK, Olejniczak M. Routine postoperative care of patients undergoing coronary artery bypass grafting on cardiopulmonary bypass. Seminars in Cardiothoracic and Vascular Anesthesia 2015; 19 (2):78-86.
  • Lighthall G, Vazquez-Guillamet C. Decision-making in critical care medicine. Clinical Medicine and Research 2015; 13(3-4): 156-168
  • Lighthall G, Verduzco L. Survival after long-term residence in an intensive care unit. Federal Practitioner 2016; June: 18-27.
  • Bannard-Smith J, Lighthall GK, Jones DA, Subbe CP, Durham L, Welch J, Bellomo R, Subbe C for the Medical Emergency Team Hospital Outcomes in a Day (METHOD) investigators. Clinical outcomes of patients seen by Rapid Response Teams: A template for benchmarking international teams. Resuscitation. 2016 Jul 11;107:7-12.
  • Maslove DM, Chen BT-M, Wang H, Kuschner WG. The diagnosis and management of pleural effusions in the ICU. J Intensive Care Med 2013;28:24-36
  • Wang HL, Aguilera C, Knopf, KB, Chen T-M B, Maslove, DM, Kuschner WG. Thrombocytopenia in the intensive care unit. J Intensive Care Med 2013;28:268 - 80.
  • Chen T-M B, Malli H, Maslove, DM, Wang H, Kuschner WG. Toxic inhalational exposures. J Intensive Care Med 2013;28: 323-33.
  • Nguyen C, Kaku S, Tutera D, Kuschner WG, Barr J. Viral respiratory infections of adults in the intensive care unit. J Intensive Care Med 2016;31:427-41.
  • Ho JQ, Nguyen CD, Lopes R, Ezeji-Okoye SC, Kuschner WG. Spiritual care in the intensive care unit: a narrative review. J Intensive Care Med, 2017 Jan 1:885066617712677. doi: 10.1177/0885066617712677. [Epub ahead of print]
  • Sevransky JE, Checkley W, Herrera P, Pickering BW, Barr J*, Brown SM, Chang SY, Chong D, Kaufman D, Fremont RD, Girard TD, Hoag J, Johnson SB, Kerlin MP, Liebler J, O'Brien J, O'Keefe T, Park PK, Pastores SM, Patil N, Pietropaoli AP, Putman M, Rice TW, Rotello L, Siner J, Sajid S, Murphy DJ, Martin GS; United States Critical Illness and Injury Trials Group-Critical Illness Outcomes Study Investigators. Protocols and hospital mortality in critically ill patients: the United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study (USCIITG-CIOS). Crit Care Med. 2015 Oct; 43(10):2076-84. (PMID: 26110488).
  • Nguyen CD, Kaku S, Tutera D, Kuschner W, Barr J. Viral respiratory infections of adults in the intensive care unit. J Intensive Care Med. 2015 May 19. [Epub ahead of print] (PMID: 25990273)
  • Mudumbai SC, Barr J, Scott J, Mariano ER, Bertaccini EJ, Nguyen HT, Memtsoudis SG, Cason B, Phibbs CS, Wagner T. Invasive mechanical ventilation in California over 2000-2009: Implications for emergency medicine. West J Emerg Med. 2015; 16(5):696-706. (PMID: 26587094)
  • Gelinas C, Berube M, Chevrier A, Pun BT, Ely WE, Skrobik Y, Barr J. Delirium Assessment Tools for use in Critically Ill Adults: A Psychometric Analysis and Systematic Review. Critical Care Nurse (In Press – July 2017)
  • Barnes-Daly MA, Pun BT, Harmon LA, Kumar VK, Schweickert WD, Engel HJ, Esbrook CL, Stollings JL, Hargett KD, Devlin JW, Carson SS, Aldrich JM, Posa PJ, Puntillo KA, Barr J, Byrum DG, Ely EW, Balas MC. Society of Critical Care Medicine’s ICU Liberation ABCDEF Bundle Improvement Collaborative: Background, Implementation Strategies, and Performance/Outcome Metrics. Critical Care Medicine (In Press)
  • Hurt CM, Ho VK, and Angelotti, T. Systematic and quantitative analysis of G protein-coupled receptor trafficking motifs. Methods Enzymology P. Michael Conn, eds. Academic Press (2013) 521:171-187.
  • Björk S, Hurt CM, Ho, VK, and Angelotti T. REEPs are membrane shaping adapter proteins that modulate specific G protein-coupled receptor trafficking by affecting ER cargo capacity. PLoS One (2013) 8:e76366.
  • Hurt CM, Björk S, Ho VK, Gilsbach, R, Hein, L, and Angelotti T. REEP1 and REEP2 proteins are preferentially expressed in neuronal and neuronal-like exocytotic tissues. Brain Research (2014) 1545:12-22.
  • Sorensen MW, Hurt CM and Angelotti T. Common alpha2 adrenergic receptor polymorphisms do not alter plasma membrane trafficking. Naunyn-Schmiedebergs Arch Pharmacol (2014) 387:569-579
  • Hurt CM and Angelotti T. Expression and trafficking of functional G protein-coupled receptors are related, yet distinct, concepts. Naunyn-Schmiedebergs Arch Pharmacol (2014) 387:1009-1012
  • Jafari A, Langen ES, Aziz N, Mihm F, Druzin ML: ‘The Effects of Respiratory Failure on Delivery in Pregnant Patients with H1N1 2009 Influenza’ Journal of Obstetrics and Gynecology 2010; 115:1033-1035
  • Mayette M, Gonda J, Hsu JL, Mihm FG: “Propofol infusion syndrome resuscitation with extracorporeal life support: a case report and review of the literature” Annals of Intensive Care 2013; 3(1):32.
  • Htet N, Vaughn J, Adigopula S, Hennessey E, Mihm F: “Needle-guided ultrasound technique for axillary artery catheter placement in critically ill patients: a case series and technique description” Journal of Critical Care 2017 (in press)

Faculty Research

Research into the problems of critically ill patients is investigated at the clinical and molecular level. The focus of our research is to improve our ability to care for patients with life-threatening disorders. Please click on faculty members below to view current research and publication history.

  • Timothy P. Angelott, MD, PhD 
    Dr. Angelotti is interested in the molecular basis for sympathetic axtivation and modulation in various disease states.
  • Edward J. Bertaccini MD
    Dr. Bertaccini is interested in the molecular mechanisms of anesthesia and sedation in the intensive care unit.
  • Ware Kuschner, MD 
    Dr. Kushner's research focuses on health effects of toxic inhalational exposure.
  • Geoff Lighthall, MD
    Dr. Lighthall is interested in the evolution of critical illnesses and its detection at a stage where intensive care can produce meaningful results. Prior work has focused on vital signs and monitoring as means of detecting deterioration as well as the development of medical emergency teams (RRTs) to deliver rapid care to unstable patients. Fellows have enjoyed working on these projects as well as those looking at the survival and function of critically ill patients seen by emergency teams and cared for in the ICU. Additionally, Dr. Lighthall is a leader in the use of simulation systems in critical care team training and as a means of evaluating care delivery systems.
  • Fred Mihm, MD 
    Dr. Mihm’s two areas of research interest involve cardiorespiratory monitoring techniques and applications and the perioperative management of patients with pheochromocytoma.