Principal Investigator and Director

Dr. Chang is a physician scientist who has pioneered studies of the noncoding genome. He is interested in how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. His team will focus on studies of lncRNA-genome interaction and clinical regulome analyses.

Co-Principal Investigators

Assistant Professor of Genetics and, by courtesy, of Applied Physics

Dr. Greenleaf is building new tools to leverage the power of high-throughput sequencing and cutting-edge microscopies, and bringing these new technologies to bear against basic biological questions of genomic and epigenomic variation. His group will focus on methods development components of the project, including transposase-based accessible chromatin methods, and higher-order structure determination.  

Stanford W. Ascherman, MD, FACS, Professor in Genetics

Dr. Snyder is a worldwide leader in applying omics approaches of genome sequencing, transcriptomics proteomics, metabolomics, DNA methylation and microbiome assays to the analysis of human disease. Dr. Snyder will coordinate the activities of the DNA methylation project and work closely with Drs. Greenleaf and Chang on the mapping of regulation information in personal genomes.

Assistant Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical Translational Neurosciences Incubator) and of Genetics

Dr. Urban is investigating the molecular effects of large genome variants during neuronal development using iPSC model systems and the study of the nature and effects of somatic genome variation in the brain using tissue culture models and primary tissue samples. Dr. Urban will focus on coordinating whole-genome sequence analyses as well as the development of the allele-specific methylome sequencing technology. 

Stephen R. Pierce Family Goldman Sachs Professor in Science and Human Health, Professor of Biomedical Data Science and, by courtesy, of Biology

Dr. Wong’s current interest centers on the application of statistics to problems arising from biology, in particular questions concerning gene regulation and signal transduction. The Wong Lab will focus on computational analysis of personal regulome data.


Nathan Boley | Kundaje Lab

Seung Woo Cho | Chang Lab

Kasey Nicole Davis | Urban Lab

Peter Frick | Greenleaf Lab

Gucci Gu | Snyder Lab

Andrew Koh | Crabtree Lab

Sandy Klemm | Greenleaf Lab

Yang Li | Pritchard Lab

Shin Lin | Snyder Lab

Ulrike Litzenburger | Chang Lab

Michelle Longmire | Chang Lab

Zhipeng Lu | Chang Lab

Jason Reuter | Snyder Lab

Viviana Risca | Greenleaf Lab

Ansuman Satpathy | Chang Lab

Hagen Tilgner | Snyder Lab

Dan Xie | Snyder Lab

Jin Xu | Chang Lab

Cliff Zhang | Chang Lab

Xianglong Zhang | Urban Lab

Graduate Students

Joey Arthur | Wong Lab

Jason Buenrostro | Chang Lab/Greenleaf Lab

Ava Carter | Chang Lab

Sarah Denny | Greenleaf Lab

Brian Do | Chang Lab

Ryan Flynn | Chang Lab

Chuan Foo | Kundaje Lab

Margaret Xing Fu | Wong Lab

Daniel Kim | Khavari Lab/Kundaje Lab

David Moskowitz | Greenleaf Lab

Jeff Quinn | Chang Lab

Adam Rubin | Khavari Lab

Alicia Schep | Greenleaf Lab

Damek Spacek | Snyder Lab

Orly Wapinski | Chang Lab

Staff Scientists

Xiaomin Bao | Khavari Lab

Kun Qu | Chang Lab/Khavari Lab

Ying Shen | Chang Lab/Khavari Lab

Yong Wang | Wong Lab


Gerald Crabtree
Pathology and Developmental Biology, Stanford University

Paul Khavari
Dermatology, Stanford University

Youn Kim
Dermatology, Stanford University

Anshul Kundaje
Genetics and Computer Science, Stanford University

Calvin Kuo
Medicine (Hematology), Stanford University

Liqun Luo
Biology, Stanford University

Emmanuel Mignot
Psychiatry, Stanford University

Dana Pe'er
Biological Sciences, Columbia University

Jonathan Pritchard
Genetics and Biology, Stanford University