Comparative Medicine

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My research focuses on understanding the neurobiology of cancer pain and acute animal pain models, and to improve clinical pain management.  This work is roughly divided into 2 parts: studying biological markers of pain pathophysiology and controlling pain in the clinical setting.  I am interested in targeted pain control such as voltage-gated sodium channels, transient receptor potential vanilloid (TRPV1) and opioids. Research methodology will be mainly using electrophysiological and behavioral techniques

Personnel

spinal cordCholawat Pacharinsak DVM, MS, PhD, DACVAA  Assistant Professor
(650) 724-9832
(650) 725-0940 (fax)

Research Collaboration

David Yeoman, PhD

Pacharinsak et al. (2008) Pain. 139(1): 34-46.

Publications

Brink TS, Pacharinsak C, Khasabov SG, Beitz AJ, Simone DA. (2011) Differential modulation of neurons in the rostral ventromedial medulla by neurokinin-1 receptors. J Neurophysiol. Oct 26

Lee AS, Xu D, Nguyen PK, Nag D, Lyons JK, Han L, Hu S, Lan F, Huang M, Liu J, Narsinh KN, Long CT, de Almeida P, Levi B, Kooreman N, Bangs C, Pacharinsak C, Yeung AC, Gambhir SS, Longaker MT, Wu JC. (2011) Preclinical derivation and imaging of autologously transplanted canine induced pluripotent stem cells. J Biol Chem. Jun 30.

McKeon GP, Pacharinsak C, Long CT, Howard AM, Jampachaisri K, Yeomans DC, Felt SA. (2011) Analgesic Effects of Tramadol, Tramadol-Gabapentin and Buprenorphine in an Incisional Model of Pain in the Rats (Rattus norvegicus). JAALAS. March 50(2): 192-197.

Long CT, Pacharinsak C, Jampachairsri K, McKeon GP, Howard AM, Albertelli MA, Felt SA. (2010) Comparison of Rectal and Tympanic Core Body temperature Measurement in Adult Guyanese Squirrel Monkeys (Saimiri sciureus sciureus). J Med. Primatol. 40: 135-141.

Wacnik, PL, Pacharinsak, C, Beitz, AJ. Animal Models of Cancer Pain. (2010)  In Ma, C and Zhang, J-M (eds): Animal Models of Pain (Neuromethods), 1st ed. Springer New York Dordrecht Heidelderg London. p.117-146. ISBN:978-1-60761-879-9

Pacharinsak C and Beitz AJ. (2008) Animal Models of Cancer Pain. Comp Med. 58(3): 220-233.

Potenzieri C, Brink T, Pacharinsak C and Simone DA. (2008) Cannabinoid Modulation of Cutaneous Ad Nociceptors during Inflammation. J Neurophysiol. 100(5): 2794-806.

Pacharinsak C, Khasabov SG, Beitz AJ and Simone DA. (2008) NK-1 Receptors in the Rostral Ventromedial Medulla Contribute to Hyperalgesia Produced by Intraplantar Injection of Capsaicin. Pain. 139(1): 34-46.

Pacharinsak C, Greene SA, Keegan RD and Kalivas PW. (2003) Postoperative Analgesia In Dogs Receiving Epidural Morphine plus Medetomidine. Journal of Veterinary Pharmacology Therapeutics (26): 71-77.

 

 

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