Comparative Medicine
Lemur peeking from inside tree

As a laboratory animal veterinarian, I collaborate with investigators to develop and refine animal models of human disease. Better animal models lead to advancement in both biomedical research and animal welfare. My focus area is cancer, particularly rodent models of glioblastoma, breast cancer, and prostate cancer. Surgical, orthotopic tumor models provide ways to test new cancer treatments, while characterization of  genetic tumor models can bring insight into tumor initiation and metastasis. I also have ongoing projects to develop and characterize rodent models of celiac disease and multiple sclerosis. Additionally, I investigate ways to improve the welfare of animals in a laboratory setting through the development and assessment of environmental enrichment methods.

MRI imaging of hMARx/TRAMP mouse prostrates

MRI imaging of h/mARxTRAMP mouse prostates (white arrows) and corresponding tumor palpation categories. Early tumors are detectable by MRI but not by palpation. Mice are palpated once a week and the majority of tumors are initially detected by palpation at status 1 (Albertelli et al, Hum Mol Genet 17:98, 2008).

Personnel

Megan Albertelli, DVM, PhD
Assistant Professor
(650) 725-3603
(650) 725-0940 (fax)

Publications

 

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