Spring Courses in Comparative Medicine
2018 - 2019 AY

COMPMED 80N: Animal behavior: sex, death, and sometimes food!

Preference to first-year students; sophomores admitted if space available.

3 units | UG Reqs: WAY-SMA | Class # 9865 | Section 01 | Grading: Letter or Credit/No Credit | ISF
09/24/2018 - 12/07/2018 Tue, Thu 11:30 AM - 1:20 PM at E.D. Stone Edwards Bldg R358 with Garner, J. (PI)
Instructors: Garner, J. (PI)
Notes: Class meets in Edwards R358. Introductory Seminar.  Advance sign-up process and deadlines at http://introsems.stanford.edu.

Preference to freshman. Behavior is what makes animals special (thirsty plants don't walk to water), but why do animals behave the way they do? What does their behavior tell us about their inner lives, and about ourselves? What do lipstick and cuckoos and fireflies have in common? Why would nobody want to be a penguin? What do mice say to each other in their pee-mail? Learning how to think about questions like these gives us a unique perspective on the natural world. Format: Discussion and criticism of video examples, documentaries, and research papers. Topics: History and approaches to animal behavior; development of behavior, from genetics to learning; mechanisms of behavior, from neurons to motivation; function of behavior, from honest signals to selfish genes; the phylogeny of behavior, from domestication to speciation; and modern applications of behavior, from abnormal behavior, to conservation, to animal welfare, and animal consciousness.

Joseph Garner, DPhil is an Associate Professor of Comparative Medicine, and Associate Professor, by courtesy, of Psychiatry and Behavioral Sciences. He received his doctoral degree in (abnormal) animal behavior at the University of Oxford, Great Britain, conducted his postdoctoral training at UC Davis, and began his faculty career at Purdue University. His research interests include the development of refined methods in behavioral research; abnormal behaviors in animals and their relationships with abnormal behaviors in humans; mouse well-being and enrichment; and the scientific impact of well-being problems in lab animals.

His favorite experiments are ones where the animals tell you what's really going on by doing the opposite of what was predicted. He became interested in animal behavior because of its potential to open a window into the experience of the animals that share our world and our lives. He pursued a career in the field because it presents some of the hardest questions and most beautiful answers in science; and because of the great potential for animal behavior to improve both the lives of animals, and also the lives of humans. He serves on the boards of both animal well-being and human mental health advocacy organizations. None of the animal members of his own family are particularly well behaved, but he prefers them that way.

For enrollment information go to Undergrad Introductory Seminar's site

COMPMED 84Q: Globally Emerging Zoonotic Diseases

Preference to sophomores; first-year students admitted if space available.                        Check out our All Quarter courses too!

3 units | UG Reqs: WAY-SMA | Class # 2060 | Section 01 | Grading: Letter or Credit/No Credit | ISS         
04/01/2019 - 06/05/2019 Mon, Wed 3:00 PM - 4:20 PM with Felt, S. (PI)
Instructors: Felt, S. (PI)
Notes: Introductory Seminar. Advance sign-up process and deadlines at http://introsems.stanford.edu. Class meets in Edwards R358.

Infectious diseases impacting veterinary and human health around the world today. Mechanisms of disease, epidemiology, and underlying diagnostic, treatment and control principles associated with these pathogens.

Stephen Felt, DVM, MPH is an Associate Professor in the Department of Comparative Medicine, School of Medicine. In his position, he performs clinical veterinary care, biomedical research and teaching. Prior to arriving at Stanford, he was stationed overseas as a US Army Veterinary Corps Officer and participated in a variety of disease outbreak investigations on the Asian and African Continents and served as a veterinary consultant to the World Health Organization. Dr. Felt earned his D.V.M. from the University of Wisconsin and his M.P.H. from the Uniformed Services University. He is a Diplomate of the American College of Veterinary Preventive Medicine and a Diplomate of the American College Laboratory Animal Medicine.

For enrollment information go to Undergrad Introductory Seminar's site

COMPMED 85N: Animal Use in Biomedical Research

Preference to first-year students; sophomores admitted if space available.                    Check out our All Quarter courses too!

3 units | Class # 2001 | Section 01 | Grading: Letter or Credit/No Credit | ISF
04/01/2019 - 06/05/2019 Tue, Thu 12:00 PM - 1:20 PM with Albertelli, M. (PI)
Instructors: Albertelli, M. (PI)
Notes: Introductory Seminar. Advance sign-up process and deadlines at http://introsems.stanford.edu.

How and why animals are used in biomedical science. Addresses human and animal disease entities and how animal research has contributed to the treatment and cure of disease. Significantnportions of this course are devoted to documenting the humane care and treatment of laboratory animals in research, including, but not limited to such topics as laws and ethics, animal behavior, animal modeling, and the animal activist movement. Course topics will also include: What advances have been made as a result of the use of animals in research? Who conducts animal research? Predominant animal species used in biomedical research, facts and myths; the regulation of biomedical research; housing and care of laboratory animals; why new drugs must be tested; animal use in stem cell research, cancer research and genetically engineered mice; career choices in biomedical research.

Megan Albertelli, DVM, PhD Assistant Professor, received her D.V.M. from Michigan State University. She completed her residency training in laboratory animal medicine and her Ph.D. in Human Genetics at the University of Michigan. Dr. Albertelli joined the Stanford Department of Comparative Medicine in 2009. Her research interests include genetic variation in breast and prostate cancers, as well as the development and refinement of mouse models of cancer and celiac disease. Dr. Albertelli is a Diplomate of the American College of Laboratory Animal Medicine.

For enrollment information go to Undergrad Introductory Seminar's site

COMPMED 202: Research Biomethodology for Laboratory Animal Science

2 units | Class # 12000 | Section 01 | Grading: Medical Satisfactory/No Credit | SEM
04/01/2019 - 06/05/2019 Fri 9:30 AM - 10:20 AM at RAF 1 with Pacharinsak, C. (PI)
Instructors: Pacharinsak, C. (PI)

Emphasis is on providing introductory training and practical, hands-on research animal biomethodology. Topics include basic care and principals guiding the use of research animals, animal health and welfare, enrichment, basic mouse handling, rodent breeding, and the principals of rodent aseptic surgery and anesthesia. The objective of this course is to teach basic skills in animal handling, animal care and biomethodological research techniques. Content delivered online and in-person.

Cholawat Pacharinsak, DVM, PhD is a veterinary anesthesiologist, an assistant professor, and the director of Anesthesia, Pain Management, and Surgery in the Department of Comparative Medicine, Stanford School of Medicine. He has a PhD in pain neuroscience, and is a Diplomate of the American College of Veterinary Anesthesia and Analgesia (DACVAA). His research interests include understanding the neurobiology of cancer pain and acute pain models using behavioral and electrophysio-logical techniques. He also focuses on how to control pain effectively in a clinical setting.

For enrollment information go to Undergrad Introductory Seminar's site.

COMPMED 205: Animal Use in Biomedical Research

3 units | Class # 12213 | Section 01 | Grading: Medical Option (Med-Ltr-CR/NC) | LEC
04/01/2019 - 06/05/2019 Tue, Thu 12:00 PM - 1:20 PM with Albertelli, M. (PI)
Instructors: Albertelli, M. (PI)
Notes: Meets in LK 308.

How and why animals are used in biomedical science. Addresses human and animal disease entities and how animal research has contributed to the treatment and cure of disease. Significant portions of this course are devoted to documenting the humane care and treatment of laboratory animals in research, including, but not limited to such topics as law and ethics, animal behavior, animal modeling, and the animal activist movement. Course topics will also include: What advances have been made as a result of the use of animals in research? Who conducts animal research? Predominant animal species used in biomedical research, facts and myths; the regulation of biomedical research; housing and care of laboratory animals; why new drugs must be tested; animal use in stem cell research, cancer research and genetically engineered mice; career choices in biomedical research.

Megan Albertelli, DVM, PhD Assistant Professor, received her D.V.M. from Michigan State University. She completed her residency training in laboratory animal medicine and her Ph.D. in Human Genetics at the University of Michigan. Dr. Albertelli joined the Stanford Department of Comparative Medicine in 2009. Her research interests include genetic variation in breast and prostate cancers, as well as the development and refinement of mouse models of cancer and celiac disease. Dr. Albertelli is a Diplomate of the American College of Laboratory Animal Medicine.

COMPMED 210: Introduction to Mouse Histopathology

3 units | Class # 11439 | Section 01 | Grading: Medical Option (Med-Ltr-CR/NC) | LEC                        Check out our All Quarters Courses too!
04/01/2019 - 06/05/2019 Mon, Wed 10:30 AM - 12:20 PM with Bouley, D. (PI); Vilches-Moure, J. (PI)
Instructors: Bouley, D. (PI); Vilches-Moure, J. (PI)

Focus is on anatomy and histology (microscopic anatomy) of the entire mouse, proper instrument handling and dissection technique, proper tissue fixation, trimming and orientation in cassettes, identification of normal organ histology on H & E-stained slides using a light microscope, use of special stains, and digital image acquisition. Basic pathological processes (inflammation, necrosis, apoptosis, hyperplasia, cancer) and how these manifest in different organs comprises the pathology aspect of this course. Participants present the pathology of their lab's mouse models. Preference to graduate students working with mouse models. Dissection labs. Comfort with mouse handling and previous participation in VSC mouse handling and euthanasia workshops recommended.

Donna Bouley, DVM, PhD, Professor received her D.V.M. from the University of Tennessee and received her Ph.D. in 1995 in Comparative and Experimental Medicine (University of Tennessee) studying the immunopathology of Herpetic Stromal Keratitis in mouse models. She obtained Diplomate status in the American College of Veterinary Pathologists in 1996, and served on the faculty at Texas A & M CVM until recruited to the Department of Comparative Medicine at Stanford in 1997. She is the Director of Necropsy Services for the VSC, and her collaborative research interests include phenotypic characterization of genetically engineered mice, host-pathogen interactions, and pathology of minimally invasive cancer treatments. Dr. Bouley founded and mentors Stanford’s community of Pre-vets and because of her extraordinary contributions to undergraduate education and to the quality of student life, was honored in 2007 as the Lloyd W. Dinkelspiel recipient, and in 2011 was appointed as the Kleinheinz Family Fellow in the Bass University Fellows in Undergraduate Education Program.

José Vilches-Moure, DVM, PhD Assistant Professor received his D.V.M. from Purdue University. He completed his residency training in Anatomic Pathology (with an emphasis in pathology of laboratory animal species) and his Ph.D. in Comparative Pathology at the University of California-Davis. He joined Stanford in 2015, and is the Director of the Comparative Medicine Animal Histology Service (CMAHS) Center. Dr. Vilches-Moure is a Diplomate of the American College of Veterinary Pathologists, and his collaborative research interests include cardiac development and pathology, developmental pathology, and refinement of animal models in which to study early cancer detection techniques. His teaching interests include comparative anatomy, general pathology, comparative pathology, and pathology of laboratory animal species.

For enrollment information go to Stanford University Registrar's site