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Brain Response to Treatment for Pediatric PTSD
Not Recruiting
Trial ID: NCT01806701
Purpose
This study will examine how brain activation changes as a result of behavioral treatment for
posttraumatic stress disorder (PTSD) in adolescents. The investigators will conduct
functional magnetic resonance imaging (fMRI) scans before and after the widely-used
trauma-focused cognitive behavioral therapy to better understand how the brain recovers from
illness. This study will provide much needed information about brain abnormalities in abused
youth, and could lead to improvements in behavioral treatments for patients who do not
respond to current treatments.
Official Title
Biomarkers of Clinical Response to Cognitive Treatment of PTSD in Youth
Eligibility
Inclusion Criteria:
- ages 12-17, history of physical or sexual abuse, witnessing violence, or bullying; and
English speaking
Exclusion Criteria:
- receiving other psychotherapy currently, taking medications for a psychiatric disorder
currently, history of head injury with loss of consciousness longer than 5 minutes;
major medical condition such as epilepsy, diabetes, heart disease, or loss of hearing
or vision, developmental disorder such as fragile X, autism, or Down's Syndrome, MRI
contraindications including metal in the body from an injury or surgery,
non-removeable piercings, or braces, Intelligence Quotient (IQ) < 70; schizophrenia,
bipolar disorder, current substance abuse.
Intervention(s):
behavioral: Trauma-focused cognitive behavioral therapy
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Amy Garrett
650-736-1874