CHRI Faculty Scholars team up to transform the science and treatment of concussion
By Laura Hedli
David Camarillo, PhD and Gerald Grant, MD are among the nation’s foremost concussion experts and teaming up to transform the science and treatment of head injuries. They are CHRI Faculty Scholars and have received several grants towards concussion-specific research efforts.
Dr. Crystal Mackall awarded $11.9M for anti-leukemia clinical trial
Crystal Mackall, professor of pediatrics and of medicine at the School of Medicine, was awarded $11.9 million by the California Institute for Regenerative Medicine(CIRM) to fund a anti-leukemia clinical trial.
Scientists find possible autism biomarker in cerebrospinal fluid
In a recent study, Stanford scientists have found low levels of a hormone called vasopressin are linked to low social ability in monkeys and to autism in children. CHRI awardee, Karen Parker, PhD, is the lead author of this study.
Stanford team tests sleep monitoring for asthma patients
Pediatric pulmonologist and CHRI member, David Cornfield, MD and a group of colleague are testing a new monitoring approach that uses data collected during sleep.
Innovative ideas and research at the Stanford 2018 Childx
Over 30 speakers from bioengineering to psychology took the stage at the third Childx conference earlier this month on Stanford campus and delivered the latest developments and advancements in children’s health.
Stanford Childx 2018: Big ideas for little patients
Highlights from Childx, a cross-disciplinary science, medicine, public policy and healthcare symposium on research developments and opportunities for improving pediatric care.
Dr. Mary Leonard Receives Silicon Valley Tribute to Women Award
Mary Leonard, MD, MSCE, executive director of the CHRI, has been selected as one of the recipients of the 2018 YWCA Silicon Valley Tribute to Women. She is honored for her significant contributions to the Silicon Valley through their leadership in medicine and health care.
Altered immune cells clear childhood brain tumor in mice
Recent study published in Nature Medicine demonstrates the first time a severe brainstem cancer has been eradicated in mice with the tumor. The senior authors are CHRI members, Michelle Monje, MD, PhD and Crystal Mackall, MD.
Precision health and growth mindsets at Childx
The third Childx conference was held last week at Stanford, hosted by the Child Health Research Institute. Hundreds of pediatricians, educators, scientists and policy experts attended the TED-style event to address challenges and solutions in child health.
Using big data to understand the disappearing American dream at Childx
Stanford economist Raj Chetty, PhD, delivers his keynote session at last week's Childx conference on the American dream of children growing up to earn more than their parents is harder to achieve than it used to be.
Tackling childhood obesity at Childx
Speakers at Childx, including Stanford Medicine pediatrician Tom Robinson, MD, explore novel approaches to tackling the challenging issues in childhood obesity.
Stanford’s Childx conference starts today. Jump in!
Today marks the start of Stanford's third Childx conference, a TED-style event addressing challenges and solutions in child health.
Upcoming Childx conference will highlight collaborative solutions in child health
Next month, experts from many fields will convene at Stanford's third Childx conference to discuss challenges and solutions in child health. Heidi Feldman, MD and David Cornfield, MD, co-chairs of the conference share insights on this year's event.
The complex nature of concussion
A recent report in Physical Review Letters look at the complex nature of concussion, led by a team working under David Camarillo, PhD, an assistant professor of bioengineering and a member of the CHRI.
Countdown to Childx: What doctors can do to improve health literacy
Health literacy means doctors explaining health care tasks - such as giving a child medication - in doable steps that don’t make you feel like you’re overwhelmed, says health-literacy expert Ruth Parker, a guest at next month's Childx conference.
Countdown to Childx: Medical device innovation for kids with chronic disease
Pediatric cardiologist and biomedical innovator Bronwyn Harris talks about the challenge of translating data into better outcomes for kids with chronic diseases. Dr. Harris will speak at the upcoming Childx conference.
Countdown to Childx: Bioethics in pediatrics
The Childx conference, a TED-style event happening next week at Stanford, will feature a keynote session by bioethicist Jeffrey Kahn, PhD, director of the Johns Hopkins Berman Institute of Bioethics.
Dr. Gary Shaw appointed to endowed position
Gary Shaw, DrPH, professor of pediatrics, has been appointed to an endowed position in the School of Medicine. Dr. Shaw is a CHRI member and serves as a panel chair on one of the Institute's funding programs.
Sergiu P. Pasca, MD has figured out how to grow brain-like blobs in lab dishes, which could give insights into the biology of neuropsychiatric diseases like autism and aid in the understanding of fetal brain development in other neurodevelopmental disorders.
Dr. Crystal Mackall wins national award for cancer research
Crystal Mackall, MD and her co-investigators won a 2018 Top 10 Clinical Research Achievement Award for their research in pediatric cancer. Dr. Mackall is a member of the CHRI and recently spoke at the inaugural education seminar.
Researchers identify renegade cells that spur relapse in children with leukemia
Stanford researchers have published a paper in Nature Medicine that describes a technique to determine at diagnosis whether children with acute lymphoblastic leukemia would relapse. Authors included CHRI members Kara Davis, DO; Norman Lacayo, MD; Robert Tibshirani, PhD; Garry Nolan, PhD.
Recent deployment linked to higher risk of premature delivery
Giving birth soon after military deployment is linked to greater risk of premature delivery, according to a study of U.S. servicewomen led by author Jonathan Shaw, MD, a member of the CHRI.
CHRI co-sponsors 2nd annual Center for Definitive and Curative Medicine Symposium
With the support of the CHRI and the Lucile Packard Children's Hospital Stanford, the Center for Definitive and Curative Medicine Symposium put on this year’s annual scientific conference.
CHRI Introduces New Seminar Series
The Stanford Child Health Research Institute will officially launch a new seminar series starting March, highlighting current research and the latest developments in maternal child health.
Taube's Gift to Launch Youth Addition, Children’s Concussion Initiatives
The Taube’s combined gift of $14.5M will enable Gerald Grant, MD, associate professor of neurosurgery and David Camarillo, PhD, assistant professor of bioengineering to advance concussion education, care and research. They will speak about this topic at a champions reception the evening before the Childx conference.
Awardees Selected for Bridge Funding Support Progam
The CHRI awarded two Bridge Funding Support, one to Manisha Desai, PhD, and the other to Julie Parsonnet, MD, to aid in the continuation of their research projects in maternal child health.
CHRI Funds Two Global Child Health Equity Seed Grants
The CHRI funded two Global Child Health Equity Seed Grants of $25,000 each to Jennifer Keller, PhD and Clea Sarnquist, DrPH, MPHM for projects seeking solutions to improve the health of pregnant women and children in low-resource settings.
CHRI Funds Two Diabetes Research Center Seed Grants
The CHRI funded two Stanford Diabetes Research Center (SDRC) Pilot and Feasibility seed grants, one to Eric A. Appel, PhD and the other to H. Tom Soh, PhD, in support of maternal child health related research.
Daniel Bernstein Named Associate Dean for Curriculum and Student Scholarship
Daniel Bernstein, MD, the Alfred Woodley Salter and Mabel G. Salter Professor of Pediatrics, has been appointed as the School of Medicine’s Associate Dean for Curriculum and Student Scholarship. He serves as the co-chair of the Clinical Trainee Support funding program in the CHRI.
High-tech imaging could reveal mysteries of bone damage in kids with chronic disease
Mary Leonard, MD, professor and chair in the Department of Pediatrics at Stanford and the executive director of the CHRI, works to understand exactly how chronic diseases hurt children’s bone health.
Higher blood sugar in early pregnancy raises baby’s heart-defect risk
The study’s senior author, James Priest, MD, assistant professor of pediatric cardiology and recipient of a CHRI sponsored Cardiovascular Institute (CVI) seed grant award, looks at the link between high blood sugar in early pregnancies and baby's risk for heart defects.
The secret to building a strong heart lies in blood vessels
A recent study has linked a cardiovascular disease to poorly developed blood vessels around the heart in babies. The study included author Joseph Wu, MD, the Simon H. Stertzer professor of cardiovascular medicine, who has served as a mentor and co-investigator on several CHRI-funded awards.
California Stem Cell Agency Awards $5.6M in Grants to Anthony Oro
The California Institute for Regenerative Medicine awarded Anthony Oro, professor of dermatology and co-director of the CHRI, $5.6 million to support his work in developing new treatments for children with a blistering skin disease.
Drug increases speed, safety of treatment for multiple food allergies
Kari Nadeau, MD, PhD, professor of medicine and of pediatrics and the director of the Sean N. Parker Center for Allergy and Asthma Research, is the co-author of this study where they looked at an asthma medication to treat children for food allergies.
Weight Gain Impact on Cardiovascular System
Stanford scientists have discovered how gaining weight changes your whole body, as described in a recent paper published online in Cell Systems. Senior authorship is shared by Michael Snyder, PhD, professor of genetics and co-investigator on a Stanford Cardiovascular Institute (CVI) seed grant sponsored by the CHRI; and Tracey McLaughlin, MD, professor of medicine, also a recipient of a CVI award funded by the CHRI.
The New Lucile Packard Children’s Hospital Stanford
The Lucile Packard Children’s Hospital Stanford opened its new main building and grounds on December 9. Designed to transform the patient and family experience, the new 521,000-square-foot building more than doubles the size of the existing pediatric and obstetric hospital campus.
Transformative Science Requires Risk
By Laura Hedli
Michelle Monje, the Anne T. and Robert M. Bass Endowed Faculty Scholar and recipient of several Child Health Research Institute grants, takes a dynamic approach to studying brain tumor growth and potential treatments.
David K. Stevenson Elected to the American Association for the Advancement of Science
David K. Stevenson, the Harold K. Faber Professor of Pediatrics and Co-Director of the Child Health Research Institute, was selected to the American Association for the Advancement of Science for his contributions in the field of neonatology and pediatrics.
Building successful futures: CHRI Transdisciplinary Initiatives Program awardee investigates the health of immigrant families and children
By Laura Hedli
Fernando Mendoza, a professor of pediatrics and the primary investigator on a CHRI Transdisciplinary Initiatives Program (TIP) grant, explores the health and well-being of children in immigrant families in California, as well as the impact of federal, state, and local policies on health outcomes.
Interview with Carol S. Dweck on Growth Mindset
The Times Higher Education recently interviewed Carol S. Dweck, a Lewis and Virginia Eaton professor of psychology, on students’ growth mindset. She is one of the keynote speakers for CHRI's upcoming sponsored event, the 2018 Childx Symposium.
The Future of Genome Editing in Human Diseases
Matthew Porteus, an associate professor of pediatrics and a CHRI-funded investigator, spoke before a U.S. Senate committee for hearing on “Gene Editing Technology: Innovation and Impact.” Also present at the hearing was Jeffrey Kahn, the Director of the Johns Hopkins Berman Institute of Bioethics and a keynote speaker for CHRI-sponsored 2018 Childx Symposium.
Publication: Macrophage-released ADAMTS1 Promotes Muscle Stem Cell Activation
Nature Communications released a recent publication on a study, funded in part by the Child Health Research Institute, that examined how hormones play a role in muscle stem cells activation and the implications for muscle growth and regeneration. The team of Stanford researchers behind this study included Brian Feldman, an assistant professor of pediatrics and a CHRI-endowed Bechtel Faculty Scholar.
**NEW** CHRI Funds Global Child Health Seed Grants
The CHRI-sponsored Global Child Health Equity (GCHE) Seed Grant program aims to support two global health seed grants of up to $25,000 each for projects seeking solutions to improve the health of pregnant women and children in low-resource settings. Deadline for proposal submission has been extended to December 15, 2017.
Children of War
Paul Wise, a professor of pediatrics and core faculty member of the Stanford Center for Health Policy, is working with colleagues to address the needs of children in areas of unstable governance and civil war.
CHRI Funds 2018 Biodesign Faculty Fellowships
As of Fiscal Year 2018, Child Health Research Institute (CHRI) will fund 50% for maternal child health Biodesign Faculty Fellowships. The fellowship provides motivated Stanford faculty members from the schools of Medicine and Engineering with advanced training and mentoring in health technology innovation.
Anthony Oro Named Co-Director of the Child Health Research Institute
The Stanford Child Health Research Institute is proud to announce a new Co-Director, Anthony Oro, MD, PhD, the Eugene and Gloria Bauer Professor in the Department of Dermatology.
Use big data
Sociologist Karen Cook and other Stanford researchers are encouraging their colleagues who study social interaction to conduct studies that examine online environments and use big data.
David Schneider appointed chair of microbiology and immunology
David Schneider, whose research focuses on resilience to infection and developing mathematical models to predict recovery and well-being, succeeds Peter Sarnow in post.
Virtual Reality imaging technology gives surgeons a better view into patient anatomy
Radiologists and surgeons at Lucile Packard Children’s Hospital Stanford are using new technology to generate easily manipulated 3-D images of patients’ anatomy from flat CT and MRI scans.
The Virtual Heart
Stanford's David M. Axelrod, MD, and David A. Sarno of Lighthaus present at the CeBIT Global Conferences.
Finding the cures within us
Stem cell research holds the promise of a sea change in medicine. At Stanford, momentum is building.
American Society of Gene and Cell Therapy Awards Maria Grazia Roncarolo 2017 Outstanding Achievement Award
Roncarolo is being recognized for her many contributions to the field of gene and cell therapy, which she will describe in an award lecture on Friday, May 12 in Washington, DC as part of the organization’s annual meeting.
Child Health Research Institute awards 26 grants for 2017
The Stanford institute’s grant program funds projects that support innovative clinical and translational research on maternal and child health.
Gene therapy for blistering skin disease appears to enhance healing in clinical trial
A trial in which genetically altered skin was grafted onto patients’ chronic wounds marks the first time that skin-based gene therapy has been demonstrated to be safe and effective in humans.
5 Questions: Halpern-Felsher on teens’ misconceptions about marijuana
A survey of hundreds of California high-school students shows that teens don’t understand the risks of marijuana use, and are more likely to smoke it if they have seen marijuana ads.
Researchers take step toward gene therapy for sickle cell disease
Using the CRISPR gene-editing technique in stem cells, Stanford researchers repaired the gene that causes sickle cell disease, and the mended stem cells were successfully transplanted into mice.
Traumatic stress changes brains of boys, girls differently
A brain region that integrates emotions and actions appears to undergo accelerated maturation in adolescent girls with PTSD, but not in boys with the condition, a Stanford study has found.
Stanford patient was first to receive lifesaving drug as an infant
Four-year-old Zoe Harting is doing well after participating in a phase-2 clinical trial of the first drug for a deadly genetic disease, spinal muscular atrophy type 1.
What Happened Within This Player’s Skull
Information from mouth guard sensors, developed by bioengineer David Camarillo and his team at the Cam Lab, provide a more detailed and precise window into what was happening within a football player’s brain within milliseconds after a hit.
Stanford researchers expand comparison of males and females with anorexia
Recently, a team of researchers from Stanford and other universities have published a series of papers to help fill this knowledge gap.
Conjoined twins successfully separated at Packard Children’s Hospital
Two-year-old twin sisters Erika and Eva Sandoval are recovering in the pediatric intensive care unit following their Dec. 6 separation surgery.
Researchers develop new compound to reduce tumor growth
Researchers at Stanford found that a new cell surface receptor they created is effective at inhibiting cancer growth in mice.