The New, Improved World of Infant Care
Six research centers are finding new ways to prevent premature birth, which affects one in 10 infants and can cause serious and costly mental and physical disabilities.
How Blood Will Soon Tell Us Everything
Recent studies show you can predict a woman’s due date within a two-week window from a blood test. Bill Gates highlights the work of Stephen Quake, a professor of bioengineering and of applied physics, and how noninvasive blood tests are the future of health care.
Inaugural research symposium set for November 16
The inaugural CHRI Symposium, scheduled for Friday, November 16th at the Stanford University Li Ka Shing Center for Learning & Knowledge, will highlight the latest developments in maternal child health research from across the campus. Registration is now open.
CHRI awards $800K to four Transdisciplinary Disciplinary Initiative Projects in 2018
The CHRI awards a total of $800,000 to four Transdisciplinary Disciplinary Initiative research projects led by teams from different schools to work together on innovative projects with significant impact in maternal and child health. Read more.
CHRI awards $3.3.M to 44 clinical fellows, postdocs, and master’s students in 2018
The CHRI awards a total of $3,364,982 to 26 clinical trainees, 14 postdoctoral researchers, and 4 master’s students who are pursuing clinical and translational research in maternal and child health. Read more.
CHRI awards over half a million dollars to 16 Pilot Grants in 2018
The CHRI awards a total of $541,026 to 16 pilot grants in three categories: Early Career Pilot grants for instructors and assistant professors, New Ideas grants for mid to senior investigators, and Clinician Educators grants for clinical instructors or above. Read more.
Stanford Medicine honors Christopher Dawes, a transformational leader
The longtime CEO of Lucile Packard Children’s Hospital Stanford, Christopher Dawes, has retired after nearly three decades of shaping health care for children and expectant mothers.
How Stanford research is making MRI scans safer for kids
Shreyas Vasanawala, professor of radiology, is tailoring MRI equipment to children. In this Q&A, he discusses how his work allows young patients to receive faster MRI exams that require less anesthesia.
A closer look at the powerhouses of the cell, mitochondria
Daniel Bernstein, MD, the Alfred Woodley Salter and Mabel G. Salter Endowed Professor, recently gave a lecture at the CHRI Seminar Series on an imaging technique for assessing the diversity of mitochondria.
Stanford study shows how head and neck positioning affects concussion risk
Stanford researchers are working with a model they developed in David Camarillo’s lab to stimulate how head and neck positioning during an impact affects rotational acceleration resulting from the impact.
CHRI awardees Ricardo Dometsch and Sergiu Pasca venture into the emerging field of molecular psychiatry
Neuroscientists Ricardo Dolmetsch, PhD, and Sergiu Pasca, MD, each received funding from the CHRI early on to help support their collaborative and innovative work in understanding the development of human brain disorders.
Rosenkranz Prize winner hopes to develop malaria vaccine for pregnant women
Prasanna Jagannathan, MD, assistant professor of medicine, received the 2018 Rosenkranz Prize, which he hopes to use to develop a malaria vaccine for pregnant women. He received a CHRI award for his pilot work on malaria chemoprevention in pregnancy and transfer of antimalarial antibodies to newborns.
Google Glass helps kids with autism read facial expressions
Children with autism were able to improve their social skills by using a smartphone app paired with Google Glasses, according to a study led by senior author and CHRI member, Dennis Wall, PhD, associate professor of pediatrics and of biomedical data science.
New CEO of Lucile Packard Foundation for Children’s Health appointed
Cynthia Brandt Stover has been appointed president and CEO of the Lucile Packard Foundation for Children’s Health. The foundation directs all fundraising for the Stanford Children’s Hospital and for the maternal and child health programs at the School of Medicine.
Brain scans yield more clues to autism
Children with autism have structural and functional abnormalities in the brain circuit that normally makes social interaction feel rewarding, according to a recent study. Vinod Menon, PhD, professor of psychiatry and behavioral sciences, is the senior author.
Lucile Packard Children’s Hospital Stanford among the nation’s best pediatric hospitals
U.S. News & World Report once again ranks Lucile Packard Children’s Hospital Stanford among the nation’s best pediatric hospitals for the 14th consecutive year.
Dr. Yvonne Maldonado celebrated for her accomplishments in pediatric research
Yvonne Maldonado, MD, senior associate dean for faculty development and diversity and professor of pediatrics, is celebrated for her perseverance and accomplishments in pediatric research.
A rare disease inspires a Stanford team to develop a new test
Fanconi anemia is a rare but deadly disease and there are no good drugs to treat its root cause, but Stanford researchers, including Eric Kool, PhD, and Kenneth Weinberg, MD, and collaborator Daria Mochly-Rosen, PhD, are developing a test that could help kids with the disease.
Separation from parents removes children’s most important protection
Stanford psychologist Ian H. Gotlib discusses the psychological effects of early-life stress and parental separation. Gotlib’s research has shown that children need their parents for their own emotional well-being.
Genetic variation in progesterone receptor tied to prematurity risk
Humans have unexpectedly high genetic variation in the receptor for a key pregnancy-maintaining hormone, according to research led by Stanford scientist. Gary Shaw, DrPH, and David Stevenson, MD, both professors of pediatrics, share senior authorship of this study.
CHRI Announcement: Funding Increase for the Postdoctoral Support Program FY 2019
The CHRI is pleased to announce an increase in funding through its Postdoctoral Support Program to match the campus-wide minimum for postdoctoral fellows.
Faculty Scholar shares experience in the Eureka program for translational medicine
The CHRI sponsored several Stanford faculty, including hematologist/oncologist Anupama Narla, MD, to attend a seven-day course in translational medicine at the Eureka Institute for Translational Medicine in Siracusa, Italy.
The long-term vision in science: Faculty Scholar finds her Eureka moment as a translational scientist
Psychiatrist and behavioral scientist Manpreet Singh, MD, MS, shares her journey as translational researcher and the impact of the multiple awards she has received from the CHRI in her work, including the most recent opportunity to attend an intensive course at the Eureka Institute for Translational Medicine in Siracusa, Italy.
Ms. Hosna Omarzad receives Donna Schurr Spirit Award
The CHRI is proud to announce Ms. Hosna Omarzad as the recipient of the 2018 Donna Schurr Spirit Award, given by the Department of Pediatrics at the Stanford School of Medicine for an outstanding staff member for their outstanding performance and dedication.
Blood test might predict pregnancy due date and preterm birth
A Stanford-led team has developed a blood test that can give a reliable estimate of the baby’s due date and can predict if the baby will arrive prematurely. Study included co-senior author Stephen Quake, PhD, a professor of bioengineering and of applied physics.
Researchers team up to develop new life-saving antibiotics that will not cause deafness in children
Anthony Ricci, PhD, a professor of otolaryngology, and Alan Cheng, MD, an associate professor of otolaryngology, are developing new life-saving antibiotics that will not cause deafness in children. This project was supported by SPARK, funded in part by the CHRI for projects focused in maternal and child health. See article in Stanford Medicine magazine and blog post in Scope.
Link between birth weight and adult metabolic health
New research examines the relationships between birth weight and metabolic and cardiovascular disease in adults. Thomas Robinson, MD, MPH, an expert in childhood obesity and a CHRI executive committee member, provides his take in the article.
Health Innovation Opportunities for 2017-2018 Stanford Biodesign Faculty Fellows
The Stanford Biodesign Faculty Fellowship provides motivated Stanford University faculty members from the schools of Medicine and Engineering with advanced training and mentoring in health technology innovation. Six participants were partially funded by the CHRI.
New Precision Health and Integrated Diagnostics Center sets out to stop disease before it starts
Officially established last year, the Stanford Precision Health and Integrated Diagnostics Center brings together scientists from across campus to focus on precision health and integrated diagnostics. The center’s team of scientists includes members from the CHRI.
Dr. Crystal Mackall awarded $11.9M for anti-leukemia clinical trial
Crystal Mackall, professor of pediatrics and of medicine at the School of Medicine, was awarded $11.9 million by the California Institute for Regenerative Medicine(CIRM) to fund a anti-leukemia clinical trial.
Scientists find possible autism biomarker in cerebrospinal fluid
In a recent study, Stanford scientists have found low levels of a hormone called vasopressin that are linked to low social ability in monkeys and to autism in children. CHRI awardee, Karen Parker, PhD, is the lead author of this study.
CHRI Faculty Scholars team up to transform the science and treatment of concussion
By Laura Hedli
David Camarillo, PhD and Gerald Grant, MD are among the nation’s foremost concussion experts and teaming up to transform the science and treatment of head injuries. They are CHRI Faculty Scholars and have received several grants towards concussion-specific research efforts.
Transformative Science Requires Risk
By Laura Hedli
Michelle Monje, the Anne T. and Robert M. Bass Endowed Faculty Scholar and recipient of several Child Health Research Institute grants, takes a dynamic approach to studying brain tumor growth and potential treatments.
Building successful futures: CHRI Transdisciplinary Initiatives Program awardee investigates the health of immigrant families and children
By Laura Hedli
Fernando Mendoza, a professor of pediatrics and the primary investigator on a CHRI Transdisciplinary Initiatives Program (TIP) grant, explores the health and well-being of children in immigrant families in California, as well as the impact of federal, state, and local policies on health outcomes.
Countdown to Childx: Bioethics in pediatrics
The Childx conference, a TED-style event happening next week at Stanford, will feature a keynote session by bioethicist Jeffrey Kahn, PhD, director of the Johns Hopkins Berman Institute of Bioethics.
Stanford Childx 2018: Big ideas for little patients
Highlights from Childx, a cross-disciplinary science, medicine, public policy and healthcare symposium on research developments and opportunities for improving pediatric care.
Dr. Mary Leonard Receives Silicon Valley Tribute to Women Award
Mary Leonard, MD, MSCE, executive director of the CHRI, has been selected as one of the recipients of the 2018 YWCA Silicon Valley Tribute to Women. She is honored for her significant contributions to the Silicon Valley through their leadership in medicine and health care.
Altered immune cells clear childhood brain tumor in mice
Recent study published in Nature Medicine demonstrates the first time a severe brainstem cancer has been eradicated in mice with the tumor. The senior authors are CHRI members, Michelle Monje, MD, PhD and Crystal Mackall, MD.
Precision health and growth mindsets at Childx
The third Childx conference was held last week at Stanford, hosted by the Child Health Research Institute. Hundreds of pediatricians, educators, scientists and policy experts attended the TED-style event to address challenges and solutions in child health.
Using big data to understand the disappearing American dream at Childx
Stanford economist Raj Chetty, PhD, delivers his keynote session at last week's Childx conference on the American dream of children growing up to earn more than their parents is harder to achieve than it used to be.
Tackling childhood obesity at Childx
Speakers at Childx, including Stanford Medicine pediatrician Tom Robinson, MD, explore novel approaches to tackling the challenging issues in childhood obesity.
Stanford’s Childx conference starts today. Jump in!
Today marks the start of Stanford's third Childx conference, a TED-style event addressing challenges and solutions in child health.
Upcoming Childx conference will highlight collaborative solutions in child health
Next month, experts from many fields will convene at Stanford's third Childx conference to discuss challenges and solutions in child health. Heidi Feldman, MD and David Cornfield, MD, co-chairs of the conference share insights on this year's event.
The complex nature of concussion
A recent report in Physical Review Letters look at the complex nature of concussion, led by a team working under David Camarillo, PhD, an assistant professor of bioengineering and a member of the CHRI.
Countdown to Childx: What doctors can do to improve health literacy
Health literacy means doctors explaining health care tasks - such as giving a child medication - in doable steps that don’t make you feel like you’re overwhelmed, says health-literacy expert Ruth Parker, a guest at next month's Childx conference.
Countdown to Childx: Medical device innovation for kids with chronic disease
Pediatric cardiologist and biomedical innovator Bronwyn Harris talks about the challenge of translating data into better outcomes for kids with chronic diseases. Dr. Harris will speak at the upcoming Childx conference.
Recent study suggest that pediatric obesity and depression are connected in the brain
Early-life obesity and depression may be driven by shared abnormalities in brain regions that process rewards, according to a recent study with lead authorship by Manpreet Singh, MD, assistant professor of psychiatry and behavioral sciences and a member of the CHRI.
Innovative ideas and research at the Stanford 2018 Childx
Over 30 speakers from bioengineering to psychology took the stage at the third Childx conference earlier this month on Stanford campus and delivered the latest developments and advancements in children’s health.
Stanford team tests sleep monitoring for asthma patients
Pediatric pulmonologist and CHRI member, David Cornfield, MD and a group of colleagues are testing a new monitoring approach that uses data collected during sleep.
CHRI Funds Two Diabetes Research Center Seed Grants
The CHRI funded two Stanford Diabetes Research Center (SDRC) Pilot and Feasibility seed grants, one to Eric A. Appel, PhD and the other to H. Tom Soh, PhD, in support of maternal child health related research.
CHRI Introduces New Seminar Series
The Stanford Child Health Research Institute will officially launch a new seminar series starting March, highlighting current research and the latest developments in maternal child health.
The secret to building a strong heart lies in blood vessels
A recent study has linked a cardiovascular disease to poorly developed blood vessels around the heart in babies. The study included author Joseph Wu, MD, the Simon H. Stertzer professor of cardiovascular medicine, who has served as a mentor and co-investigator on several CHRI-funded awards.
Daniel Bernstein Named Associate Dean for Curriculum and Student Scholarship
Daniel Bernstein, MD, the Alfred Woodley Salter and Mabel G. Salter Professor of Pediatrics, has been appointed as the School of Medicine’s Associate Dean for Curriculum and Student Scholarship. He serves as the co-chair of the Clinical Trainee Support funding program in the CHRI.
CHRI Funds Two Global Child Health Equity Seed Grants
The CHRI funded two Global Child Health Equity Seed Grants of $25,000 each to Jennifer Keller, PhD and Clea Sarnquist, DrPH, MPHM for projects seeking solutions to improve the health of pregnant women and children in low-resource settings.
Awardees Selected for Bridge Funding Support Progam
The CHRI awarded two Bridge Funding Support, one to Manisha Desai, PhD, and the other to Julie Parsonnet, MD, to aid in the continuation of their research projects in maternal child health.
Taube's Gift to Launch Youth Addition, Children’s Concussion Initiatives
The Taube’s combined gift of $14.5M will enable Gerald Grant, MD, associate professor of neurosurgery and David Camarillo, PhD, assistant professor of bioengineering to advance concussion education, care and research. They will speak about this topic at a champions reception the evening before the Childx conference.
CHRI co-sponsors 2nd annual Center for Definitive and Curative Medicine Symposium
With the support of the CHRI and the Lucile Packard Children's Hospital Stanford, the Center for Definitive and Curative Medicine Symposium put on this year’s annual scientific conference.
Recent deployment linked to higher risk of premature delivery
Giving birth soon after military deployment is linked to greater risk of premature delivery, according to a study of U.S. servicewomen led by author Jonathan Shaw, MD, a member of the CHRI.
Researchers identify renegade cells that spur relapse in children with leukemia
Stanford researchers have published a paper in Nature Medicine that describes a technique to determine at diagnosis whether children with acute lymphoblastic leukemia would relapse. Authors included CHRI members Kara Davis, DO; Norman Lacayo, MD; Robert Tibshirani, PhD; Garry Nolan, PhD.
Dr. Crystal Mackall wins national award for cancer research
Crystal Mackall, MD and her co-investigators won a 2018 Top 10 Clinical Research Achievement Award for their research in pediatric cancer. Dr. Mackall is a member of the CHRI and recently spoke at the inaugural education seminar.
Sergiu P. Pasca, MD has figured out how to grow brain-like blobs in lab dishes, which could give insights into the biology of neuropsychiatric diseases like autism and aid in the understanding of fetal brain development in other neurodevelopmental disorders.
Dr. Gary Shaw appointed to endowed position
Gary Shaw, DrPH, professor of pediatrics, has been appointed to an endowed position in the School of Medicine. Dr. Shaw is a CHRI member and serves as a panel chair on one of the Institute's funding programs.
David K. Stevenson Elected to the American Association for the Advancement of Science
David K. Stevenson, the Harold K. Faber Professor of Pediatrics and Co-Director of the Child Health Research Institute, was selected to the American Association for the Advancement of Science for his contributions in the field of neonatology and pediatrics.
The New Lucile Packard Children’s Hospital Stanford
The Lucile Packard Children’s Hospital Stanford opened its new main building and grounds on December 9. Designed to transform the patient and family experience, the new 521,000-square-foot building more than doubles the size of the existing pediatric and obstetric hospital campus.
Weight Gain Impact on Cardiovascular System
Stanford scientists have discovered how gaining weight changes your whole body, as described in a recent paper published online in Cell Systems. Senior authorship is shared by Michael Snyder, PhD, professor of genetics and co-investigator on a Stanford Cardiovascular Institute (CVI) seed grant sponsored by the CHRI; and Tracey McLaughlin, MD, professor of medicine, also a recipient of a CVI award funded by the CHRI.
Drug increases speed, safety of treatment for multiple food allergies
Kari Nadeau, MD, PhD, professor of medicine and of pediatrics and the director of the Sean N. Parker Center for Allergy and Asthma Research, is the co-author of this study where they looked at an asthma medication to treat children for food allergies.
California Stem Cell Agency Awards $5.6M in Grants to Anthony Oro
The California Institute for Regenerative Medicine awarded Anthony Oro, professor of dermatology and co-director of the CHRI, $5.6 million to support his work in developing new treatments for children with a blistering skin disease.
Higher blood sugar in early pregnancy raises baby’s heart-defect risk
The study’s senior author, James Priest, MD, assistant professor of pediatric cardiology and recipient of a CHRI sponsored Cardiovascular Institute (CVI) seed grant award, looks at the link between high blood sugar in early pregnancies and baby's risk for heart defects.
High-tech imaging could reveal mysteries of bone damage in kids with chronic disease
Mary Leonard, MD, professor and chair in the Department of Pediatrics at Stanford and the executive director of the CHRI, works to understand exactly how chronic diseases hurt children’s bone health.
Interview with Carol S. Dweck on Growth Mindset
The Times Higher Education recently interviewed Carol S. Dweck, a Lewis and Virginia Eaton professor of psychology, on students’ growth mindset. She is one of the keynote speakers for CHRI's upcoming sponsored event, the 2018 Childx Symposium.
The Future of Genome Editing in Human Diseases
Matthew Porteus, an associate professor of pediatrics and a CHRI-funded investigator, spoke before a U.S. Senate committee for hearing on “Gene Editing Technology: Innovation and Impact.” Also present at the hearing was Jeffrey Kahn, the Director of the Johns Hopkins Berman Institute of Bioethics and a keynote speaker for CHRI-sponsored 2018 Childx Symposium.
Publication: Macrophage-released ADAMTS1 Promotes Muscle Stem Cell Activation
Nature Communications released a recent publication on a study, funded in part by the Child Health Research Institute, that examined how hormones play a role in muscle stem cells activation and the implications for muscle growth and regeneration. The team of Stanford researchers behind this study included Brian Feldman, an assistant professor of pediatrics and a CHRI-endowed Bechtel Faculty Scholar.
**NEW** CHRI Funds Global Child Health Seed Grants
The CHRI-sponsored Global Child Health Equity (GCHE) Seed Grant program aims to support two global health seed grants of up to $25,000 each for projects seeking solutions to improve the health of pregnant women and children in low-resource settings. Deadline for proposal submission has been extended to December 15, 2017.
Children of War
Paul Wise, a professor of pediatrics and core faculty member of the Stanford Center for Health Policy, is working with colleagues to address the needs of children in areas of unstable governance and civil war.
CHRI Funds 2018 Biodesign Faculty Fellowships
As of Fiscal Year 2018, Child Health Research Institute (CHRI) will fund 50% for maternal child health Biodesign Faculty Fellowships. The fellowship provides motivated Stanford faculty members from the schools of Medicine and Engineering with advanced training and mentoring in health technology innovation.
Anthony Oro Named Co-Director of the Child Health Research Institute
The Stanford Child Health Research Institute is proud to announce a new Co-Director, Anthony Oro, MD, PhD, the Eugene and Gloria Bauer Professor in the Department of Dermatology.
Use big data
Sociologist Karen Cook and other Stanford researchers are encouraging their colleagues who study social interaction to conduct studies that examine online environments and use big data.
David Schneider appointed chair of microbiology and immunology
David Schneider, whose research focuses on resilience to infection and developing mathematical models to predict recovery and well-being, succeeds Peter Sarnow in post.
Virtual Reality imaging technology gives surgeons a better view into patient anatomy
Radiologists and surgeons at Lucile Packard Children’s Hospital Stanford are using new technology to generate easily manipulated 3-D images of patients’ anatomy from flat CT and MRI scans.
The Virtual Heart
Stanford's David M. Axelrod, MD, and David A. Sarno of Lighthaus present at the CeBIT Global Conferences.
Finding the cures within us
Stem cell research holds the promise of a sea change in medicine. At Stanford, momentum is building.
American Society of Gene and Cell Therapy Awards Maria Grazia Roncarolo 2017 Outstanding Achievement Award
Roncarolo is being recognized for her many contributions to the field of gene and cell therapy, which she will describe in an award lecture on Friday, May 12 in Washington, DC as part of the organization’s annual meeting.
Child Health Research Institute awards 26 grants for 2017
The Stanford institute’s grant program funds projects that support innovative clinical and translational research on maternal and child health.
Gene therapy for blistering skin disease appears to enhance healing in clinical trial
A trial in which genetically altered skin was grafted onto patients’ chronic wounds marks the first time that skin-based gene therapy has been demonstrated to be safe and effective in humans.
5 Questions: Halpern-Felsher on teens’ misconceptions about marijuana
A survey of hundreds of California high-school students shows that teens don’t understand the risks of marijuana use, and are more likely to smoke it if they have seen marijuana ads.
Researchers take step toward gene therapy for sickle cell disease
Using the CRISPR gene-editing technique in stem cells, Stanford researchers repaired the gene that causes sickle cell disease, and the mended stem cells were successfully transplanted into mice.
Traumatic stress changes brains of boys, girls differently
A brain region that integrates emotions and actions appears to undergo accelerated maturation in adolescent girls with PTSD, but not in boys with the condition, a Stanford study has found.
Stanford patient was first to receive lifesaving drug as an infant
Four-year-old Zoe Harting is doing well after participating in a phase-2 clinical trial of the first drug for a deadly genetic disease, spinal muscular atrophy type 1.
What Happened Within This Player’s Skull
Information from mouth guard sensors, developed by bioengineer David Camarillo and his team at the Cam Lab, provide a more detailed and precise window into what was happening within a football player’s brain within milliseconds after a hit.
Stanford researchers expand comparison of males and females with anorexia
Recently, a team of researchers from Stanford and other universities have published a series of papers to help fill this knowledge gap.
Conjoined twins successfully separated at Packard Children’s Hospital
Two-year-old twin sisters Erika and Eva Sandoval are recovering in the pediatric intensive care unit following their Dec. 6 separation surgery.
Researchers develop new compound to reduce tumor growth
Researchers at Stanford found that a new cell surface receptor they created is effective at inhibiting cancer growth in mice.