Systems Biology of Cancer

May 2-3, 2011

The Stanford CCSB will hold its first Annual Symposium at the Bechtel Conference Center. This conference is designed for participants to explore systems biology approaches that aim to elucidate the role of differentiation, self-renewal, stem cells in cancer initiation, progression and treatment.

Program:

May 2nd

• 7:30-8:00 am Registration & Check-in, Continental Breakfast
• 8:00-8:15 Welcome & Overview
  Sylvia Plevritis, PhD, Radiology, Stanford University
• 8:15-8:55 A Systems Biology Approach to Identify Oncogene and Non-oncogene Dependencies in Human Malignancies
  Andrea Califano, PhD Biomedical Informatics, Columbia University
• 8:55-9:35 34 Parameter Single-cell Mass Cytometry Delineates Clinically and Mechanistically Relevant Leukemic Differentiation Substructures
  Garry Nolan, PhD Microbiology and Immunology, Stanford University
• 9:35-10:15 Systems Biological Approach to Understanding and Predicting Oncogene Addiction
  Dean Felsher, MD, PhD Medicine/Oncology, Stanford University
• 10:15-10:30 Break
• 10:30-11:10 The Intersectome: Tools and Ideas about Integrating Knowledge in Systems Pharmacology
  Avi Ma'ayan, PhD Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine
• 11:10-11:50 Cancer Stem Cells, Tumor Dormancy and Self-metastatic Growth
  Heiko Enderling, PhD Electrical Engineering, Columbia University
• 11:50-1:05 pm Lunch
• 1:05-1:45 A Model of Differential Regulation in Immune Cell Development and Disease Progression
  Daphne Koller, PhD Computer Science, Stanford University
• 1:45-2:25 A Global Cancer Map of Associations Between Gene Expression and Clinical Outcomes
  Andrew Gentles, PhD Radiology, Stanford University
• 2:25-3:05 XVIVO - Scientific Animation of the Inner Life of a Cell
  Robert Krensel XVIVO
• 3:05-3:30 Adjourn

Program:

May 3rd

• 7:30-8:00 am Registration & Check-in, Continental Breakfast
• 8:00-8:15 Welcome & Overview
  Sylvia Plevritis, PhD, Radiology, Stanford University
• 8:15-8:55 Inappropriate Expression of Stem Cell Programs During Leukemia Development
  Scott Armstrong, MD, PhD Pediatrics, Harvard University
• 8:55-9:35 Computational and Functional Approaches to Investigation of Leukemia Stem Cells in AML
  Ravi Majeti, MD, PhD Hematology/Stem Cell Institute, Stanford University
• 9:35-9:55 Computational Detection of Aggressive Cancer Cell Subsets defined by Abnormal Signaling*
  Jonathan Irish, PhD Medicine/Oncology, Stanford University
• 9:55-10:15 Break
• 10:15-10:55 A Multi-Scale Biology Approach for Linking the Molecular Biology of Disease to Clinical Medicine
  Eric Schadt, PhD Genetics and Genomic Sciences, Mount Sinai School of Medicine
• 10:55-11:35 Weighted Gene Co-Expression Network Analysis of Multiple Independent Lung Cancer Data Sets
  Steve Horvath, PhD, ScD Biostatistics, UCLA
• 11:35-12:15 Inferring Biological Progression from High Dimensional Molecular Data
  Sylvia Plevritis, PhD, Radiology, Stanford University
• 12:35-1:45 pm Lunch
• 1:45-2:05 Single-cell Gene Expression in Normal and Cancer Stem Cells*
  Tomer Kalisky, PhD Bioengineering, Stanford University
• 2:05-2:25 Identification of Essential Genes in Prostate Adenocarcinoma and Leukemic Cell Lines using RNAi Screening*
  Paul Diehl, PhD Cellecta
• 2:25-2:45 Systematic Identification of Novel Markers of Differentiation in Human Bladder Cancer that Predict Survival*
  Debashis Sahoo, PhD Stem Cell Institute, Stanford University
• 2:45-3:05 Signaling Across Hematopoiesis: The Network Perspective*
  Karen Sachs, PhD Microbiology and Immunology, Stanford University
• 3:05-3:30 Adjourn

*Selected Short Talks

Questions?

Please contact Anita Samantaray E-mail