Career Center

Event

Title:

 

UC Berkeley | "Sensors to Monitor for Exhaled Metabolites in Human Breath: New Avenues for Disease Diagnostics" - Nano Seminar Series

Date:   Friday, November 5, 2010
Time:   2:00-3:00pm
Location:  

UC Berkeley
390 Hearst Memorial Mining Building.
Berkeley, CA

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Sponsor:   Berkeley Nanosciences and Nanoengineering Institute
Event details:  

"A wide range of both volatile organic compounds (VOCs) and non-volatile metabolites are generated by almost all biological systems, and are now thought to represent end products associated with organism physiology and metabolism. This applies to many different types of systems including humans, bacteria, trees, and plants.

In humans, several thousand metabolic chemical compounds have been detected in exhaled human breath and appear to relate to health and disease status. Because of this, human breath analysis provides a wide range of opportunities for diagnosis of pathophysiological conditions in a non-invasive and potentially inexpensive way. We hypothesize that specific breath metabolites are associated with specific human diseases. By monitoring for emitted chemicals in exhaled breath, we can develop tools for early stage asymptomatic diagnostics that can lead to early therapy and treatment.

We are developing multiple approaches to create miniature analytical sensor modules capable of integration into a single portable device for human diagnostic systems. Final system integration of devices is expected to yield analyzers that are specifically tailored for each application, have small footprints, and be adapted for field and clinic use.

Major areas of interest include: (1) identification of robust chemical biomarkers associated with diseases of interest; (2) miniaturization to produce small, portable and easy-to-use micro-total-analysis (TAS) chemical analysis systems; and (3) advanced chemometric algorithms and digital signal processing methods.

Together, all of these research thrusts are expected to produce the first generation of mobile breath analysis devices in upcoming years. Ultimately these devices will be fully utilized in medical point-of-care locations in clinical offices.

Cristina Davis groups work focuses on cutting edge research on the design and implementation of analytical sensors."

 

 


Fee:   Free to the public
     
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