Stanford Cancer Institute Directory

Cancer Stem Cells Profiles

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    The Ernest and Amelia Gallo Professor in the School of Medicine, Professor of Developmental Biology and, by courtesy, of Chemical and Systems Biology
    Professor of Biology
    The Donald E. and Delia B. Baxter Foundation Professor and Director, Baxter Laboratory for Stem Cell Biology


    Assistant Professor, Stanford University, 1978 Associate Professor, Stanford University, 1986 Professor, Stanford University, 1991
    Karel H. and Avice N. Beekhuis Professor in Cancer Biology
    Associate Professor of Medicine (Pulmonary and Critical Care)


    Dr. Tushar Desai specializes in the treatment of general pulmonary and Interstitial Lung Diseases like Idiopathic Pulmonary Fibrosis (IPF). He has practiced pulmonary medicine since 2002. Dr. Desai has a special interest in understanding the development and progression of diseases like IPF, Chronic Obstructive Pulmonary Disease (COPD), and lung adenocarcinoma, as well as in understanding how native lung stem cells function to repair the lung gas exchange surface after injury.
    Associate Professor of Radiation Oncology (Radiation Therapy)
    Assistant Professor of Pediatrics (Endocrinology)
    Reed-Hodgson Professor in Human Biology and Professor of Genetics and of Obstetrics/Gynecology (Reproductive and Stem Cell Biology)
    Professor of Developmental Biology and, by courtesy, of Medicine (Endocrinology)
    Assistant Professor of Developmental Biology (Stem Cell)


    Our laboratory at the Stanford Institute for Stem Cell Biology & Regenerative Medicine and the Department of Developmental Biology aspires to understand how different human cell-types develop from stem cells, and how developing tissues incipiently take shape and form. To this end, we have delineated a comprehensive roadmap that describes how embryonic stem cells can develop into a spectrum of over twenty different human cell types. This roadmap enabled us to generate rather uniform populations of human liver progenitors, bone progenitors and heart progenitors from embryonic stem cells, each of which could regenerate their cognate tissue upon injection into respective mouse models. This platform to produce these engraftable human tissue progenitors provides fundamental building blocks for regenerative medicine and provides an ideal venue to understand human developmental biology. In particular we are interested in questions regarding cellular signaling, developmental competence and tissue organization. Kyle received his B.A. from Rutgers University, interned with Bing Lim at the Genome Institute of Singapore, and received his Ph.D. from Stanford University (working with Irving Weissman) as a fellow of the Hertz Foundation, the National Science Foundation and the Davidson Institute of Talent Development. He then continued research as the Siebel Investigator at the Stanford Institute for Stem Cell Biology & Regenerative Medicine, and later, as an Assistant Professor of Developmental Biology and The Anthony DiGenova Endowed Faculty Scholar. His research has been recognized by the NIH Director's Early Independence Award, Donald and Delia Baxter Foundation Faculty Scholar Award, A*STAR Investigatorship, Harold Weintraub Graduate Award and Hertz Foundation Thesis Prize.