Stanford Cancer Institute Directory
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Deborah E. Addicott - John A. Kriewall and Elizabeth A. Haehl Family Professor in Pediatrics
I was appointed the first holder of the Deborah E. Addicott – John A. Kriewall and Betsy A. Haehl Family Professor in Pediatrics in February 2007, and the Katie and Paul Dougherty Medical Director of Palliative Care in August 2010. I was previously the Chairman of the Department of Pediatrics at Stanford University, where I was the Arline and Pete Harman Professor, and the Adalyn Jay Chief of Staff at Lucile Packard Children’s Hospital. I held these posts from 1993-2006 before stepping down to return to a career of clinical care, teaching, and research. I obtained both his MD and PhD from Duke University in 1970, and was a pediatric intern at the Children’s Hospital in Boston from 1970-1971. After spending two years as a Staff Associate at the National Institutes of Health, I returned to Children’s Hospital in 1973 as a pediatric resident. I completed a fellowship in Pediatric Hematology/Oncology at Children’s Hospital and the Dana Farber Cancer Institute, and was named assistant, then associate, professor of pediatrics at Harvard Medical School. In 1981, I was recruited to the University of Rochester School of Medicine and Dentistry where I was named the James P. Wilmot Associate Professor of Pediatric Oncology and Chief of the Division of Pediatric Oncology. I was promoted to Professor of Pediatrics in 1984 and Associate Chair for Research and Development in the Department of Pediatrics in 1987. From 1985-1990, I was on the Scientific Advisory Board for St. Jude’s Children’s Research Hospital. I returned to the Board in 2000, and was its Chair from 2002 to 2006. I was also a member of the NIH Hematology II Study Section and was its Chair from 1987-1988. I served on the Board of Directors of Lucile Packard Children’s Hospital, and was a Board Member of the Ronald McDonald House and the Children’s Health Council in Palo Alto, California. I was a member of the Scientific Advisory Board of Montgomery Medical Venture Fund and Gamida Cell, a biotechnology company involved in expanded cord blood stem cells. I also served on the Steering and Selection Committees of the Pediatric Scientist Development Program, and I chair the Interdisciplinary Initiatives Program Committee of Bio-X, a venture into research, education, and innovation across all scientific communities of Stanford University. I am currently a member of the Board of Trustees of the March of Dimes, and serves on its executive committee, and the Morgridge Institute for Research, a private not-for-profit institute dedicated to supporting interdisciplinary medical research at the University of Wisconsin. My research interests include: clinical trials in leukemia, mechanisms of drug resistance, and determining the roles of proteins in predicting susceptibility to, diagnosing, and treating childhood illnesses such as brain tumors, leukemia, prematurity, and inflammatory diseases. In addition, I am the medical director of the pediatric palliative care program at Lucile Packard Children’s Hospital, Stanford. I married Ilene Cohen in 1965, before starting medical school at Duke. We are celebrating our 53rd wedding anniversary in August. Our sons, Philip, age 50, a lawyer, and Jonathan, age 48, an accountant, were born at Duke Hospital. They are both married, to Nicole and Renee, respectively. They live in the Philadelphia area, and each has given us two grandchildren (Sara, 21, Ethan, 19, Brooke, 17, and Bradley, 14), and much pleasure in our lives.
Professor of Medicine (Oncology) and, by courtesy, of Otolaryngology - Head and Neck Surgery at the Stanford University Medical Center
Associate Professor of Urology, Emeritus
My main recent interest is the application of Biomedical Engineering approaches for the clinical visualization and characterization of the static and dynamic properties of pelvic floor function. This extends to ultrasound Imaging and image processing, construction of computer models and biomechanics analysis of pelvic floor function. It is envisioned that these considerations are important constituents of the clinical evaluation of patients with lower urinary tract dysfunction and urodynamics.
Professor of Pediatrics (Neonatology), Emeritus
Dr. Contag, is a Professor in the Departments of Pediatrics, Radiology and Microbiology & Immunology at Stanford University, and a member of BioX Faculty for interdisciplinary sciences, and Immunology Faculty. Dr. Contag received his B.S. in Biology from the University of Minnesota, St. Paul in 1982. He received his Ph.D. in Microbiology from the University of Minnesota, Minneapolis in 1988 where he did his dissertation research under the direction of Professors Ashley Haase and Peter Plagemann on the topic of viral infections of the central nervous system. He was a postdoctoral fellow at Stanford University from 1990-1994 in the Department of Microbiology where he studied mother-to-infant transmission of HIV, and then joined the faculty in Pediatrics at Stanford in 1995 with a joint appointment in Microbiology and Immunology and a courtesy appointment in Radiology. Dr. Contag is the Associate Chief of Neonatal and Developmental Medicine, director of Stanford’s Center for Innovation in In Vivo Imaging (SCI3) and co-director of the Molecular Imaging Program at Stanford (MIPS). Dr. Contag is a pioneer in the field of molecular imaging and is developing imaging approaches aimed at revealing molecular processes in living subjects, including humans, and advancing therapeutic strategies through imaging. His laboratory develops macroscopic and microscopic optical imaging tools and uses imaging to assess tissue responses to stress, reveal immune cell migration patterns, understand stem cell biology and advance biological therapies. He is a founding member, and a past president of the Society for Molecular Imaging, and for his fundamental contributions in imaging, is a recipient of the Achievement Award from the Society for the Molecular Imaging. Dr. Contag is a Fellow of the World Molecular Imaging Society (WMIS) and currently President Elect of WMIS. The research mission of the Contag laboratory is to develop and use noninvasive imaging tools that can simultaneously reveal the nuances of biological processes and provide an overall picture of disease states for the purpose of developing and refining novel interventions. These imaging tools are sensitive and image over a range of scales from micro- to macroscopic, and are well-suited for the in vivo study of cellular and molecular biology. For the purpose of studying tumor biology in vivo, the Contag group is developing, and using, advanced microscopic tools with the aims of detecting and studying cancer at high resolution in vivo. These approaches use micro-optics to develop miniaturized cofocal microscopes and Raman endoscopes that can reach inside the body to interrogate disease states. This is enabling point-of-care microscopy that is changing the diagnostic paradigm from biopsy and histopathology to in vivo pathology. The opportunity to study tumor margins with arrays of microscopes will enable improved tumor detection and guided resections.
Anne T. and Robert M. Bass Professor in Pediatric Pulmonary Medicine and Professor, by courtesy, of Surgery
A physician scientist, Dr. Cornfield is actively engaged in clinical medicine, teaching and research. In clinical arena, Dr. Cornfield is a Pediatrician with an active practice in both Pediatric Pulmonary Medicine and Pediatric Critical Care Medicine. In the research arena, Dr. Cornfield's lab addresses several large thematic issues. The areas of concentration include: (i) regulation of pulmonary vascular tone; (ii) oxygen sensing in the lung; (iii) biological determinants of preterm labor focusing on myometrial smooth muscle cells; (iv) developmental regulation of barrier function in the lung; and (v) the role of hypoxia-inducible factor-1 in lung development. In addition, there is an active translational research component.
Department of Pathology Professor in Experimental Pathology and Professor of Developmental Biology
Assistant Professor of Medicine (Oncology) and of Genetics
The Curtis laboratory couples innovative experimental approaches, high-throughput omic technologies, statistical inference and computational modeling to interrogate the evolutionary dynamics of tumor progression and therapeutic resistance. To this end, Dr. Curtis and her team have developed an integrated experimental and computational framework to measure clinically relevant patient-specific parameters and to measure clonal dynamics. Her research also aims to develop a systematic interpretation of genotype/phenotype associations in cancer by leveraging state-of-the-art technologies and robust data integration techniques. For example, using integrative statistical approaches to mine multiple data types she lead a seminal study that redefined the molecular map of breast cancer, revealing novel subgroups with distinct clinical outcomes and subtype-specific drivers.