ProF-SC: Prospective Family Study Cohort
From 2011-2016, the National Cancer Institute provided funding for the Breast Cancer Family Registry to address unanswered questions regarding the prediction of breast cancer risk in women from families with one or more affected family members. We collected updates through a brief follow-up questionnaire. The information we collected will help us understand: 1) an individual’s absolute risk of breast cancer given their age, family history, reproductive history and mutation status; 2) what modifiable factors may lower one’s risk of breast in the context of having a family history, 3) how women with a personal history of breast cancer can lower their risk of a new cancer, and 4) how clinical prediction models used in the clinics can be improved.
Statistical analyses are underway and published findings can be found below: