Acquisition & Reconstruction Methods
In addition to numerous specific application areas, our group spends considerable time developing new MRI techniques that can be applied broadly. These include RF pulse design, MRI pulse sequences, reconstruction algorithms and image analysis tools, as well as "packages" that combine some of these elements.
Imaging of Metabolic Activity in Osteoarthritis with PET/MRI
Osteoarthritis (OA) is a chronic, degenerative disease of the joint that is characterized by degeneration affecting all tissues in the joint.
Metallic Implant Estimation Using Susceptibility Mapping
Magnetic field patterns can be used to identify the location and shape of metal devices and render them on images.
MRI with Compressed Sensing and Variable View Sharing
A new sampling pattern enables retrospective selection of frame rates in MRI to allow for different spatiotemporal resoluiton tradeoffs and protocol optimization for different imaging applications.
Rapid Volumetric Quantification of Cartilage Biochemistry with MRI
Detection of changes in cartilage glycosaminoglycan (GAG) content and distribution are vital for early diagnosis of osteoarthritis (OA) and potential treatment monitoring.
Multiband Diffusion-Weighted Breast MRI
This novel technique reduces distortion in high-resolution diffusion MRI.
Faster MRI Near Metal Using Subsampling
Faster MRI near metal is enabled by subsampling and tightening the field of view to fit the shape of distorted slices.
Rapid 3D MRI of Breast Perfusion
Breast cancer is most often detected on MRI using contrast-enhanced imaging.
Estimation of Multiple Tissue Parameters Using the DESS Sequence
The Double-Echo Steady-State (DESS) sequence, which produces undistorted, SNR-efficient 3D scans, can provide estimates of multiple tissue parameters.
A Simple Analytic Method for Estimating T2 in the Knee from DESS
MRI measurements of the relaxation time T2 can help estimate the progression of diseases such as osteoarthritis and its associated tissue deterioration. The Double-Echo Steady-State (DESS) sequence is often used for radiographic images of the knee.