Multiband Diffusion-Weighted Breast MRI

This novel technique reduces distortion in high-resolution diffusion MRI. Diffusion MRI is often limited by blurring or distortion, which is fundamentally proportional to the field of view (FOV) of the image.  These effects can be overcome by exciting only a narrow "strip" of signal at each time.  The narrow "strips" have reduced FOV and thus reduced distortion.  In this work, we have developed a way to simultaneously excite multiple strips, and use multiple coils to separate the signals from the strips.  This enables high-resolution images with reduced distortion over the entire FOV of the subject.

Taviani V, Alley MT, Banerjee S, Nishimura DG, Daniel BL, Vasanawala SS, Hargreaves BA.  High-resolution DWI of the breast with multiband 2D RF pulses and a generalized parallel imaging reconstruction. Magn Reson Med. 2016 Jan 17. doi: 10.1002/mrm.26110.

Online Journal Article

Comparison of our new "multiband" (MB) diffusion-weighted imaging (DWI) and conventional DWI in a patient with a breast cancer.  The highlighted areas A and B show the improved sharpness of the lesion.  The "FOCUS" image is the single-strip approach which offers similar sharpness to A, but does not cover the whole breast.

Sr Res Scientist-Physical, Rad/Radiological Sciences Laboratory
(650) 498-5581
Addie and Al Macovski Professor in the School of Engineering
(650) 723-4533
Professor of Radiology (General Radiology) and, by courtesy, of Bioengineering
Associate Professor of Radiology (Pediatric Radiology)
Associate Professor of Radiology (Radiological Sciences Laboratory) and, by courtesy, of Electrical Engineering and of Bioengineering
(650) 498-5368

Valentina Taviani is an alumnus of the BMR group

Brian Hargreaves PhD

Associate Professor of Radiology, and (by courtesy) Electrical Engineering and Bioengineering

Contact Information

Lucas Center for Imaging 
1201 Welch Rd, Stanford, CA 94305-5488

Directions: Lucas Ctr. or Porter Dr. Locations