Health Research and Policy

Abstract

DATE:

May 14, 2009

TIME:

1:15 - 3:00 pm

LOCATION:

Center for Clinical Sciences Research (CCSR), Rm 4205

TITLE:

Personalized Medicine

SPEAKER:

Koustubh Ranade, Ph.D.
Associate Group Medical Director, Clinical Diagnostics, Genentech Inc.

Personalizing medicine--getting the right drug to the right patient--will become increasingly important to enhance the value of prescription drugs. Challenges to personalizing medicine include our limited understanding of underlying disease heterogeneity and the paucity of samples available from clinical trials for data-mining. I will present examples from my research demonstrating how pharmacogenetic analysis of clinical trials can provide insights into disease heterogeneity and identify genetic predictors of efficacy and safety of prescription drugs. Such predictors can be used to optimize therapy to improve patient outcomes.

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