Health Research and Policy

Abstract

DATE:

November 19, 2009

TIME:

1:15 - 3:00 pm

LOCATION:

Center for Clinical Sciences Research (CCSR), Rm 4205

TITLE:

I explain how we measure properties of the white matter in the human brain, and then ask for your help in some mathematical a nd statistical data analysis issues

SPEAKER:

Brian Wandell
Isaac and Madeline Stein Family Professor Department of Psychology

Signals between different parts of the brain are carried on long axons (the outputs of neurons). These axons, which occupy a large volume in the center of the brain, are called the white matter. In the last fifteen years, methods for processing magnetic resonance images have been developed to analyze the white matter of the human brain noninvasively. This is the only noninvasive measurement we have for understanding the white matter. There are many neurological and developmental disorders that appear to depend on the integrity of the white matter. There are opportunities to develop new algorithms to analyze these data, and there are many questions about how to approach the statistical analysis. As in the title, I will explain the measurement method (briefly) and then overview some of the interesting findings that relate white matter to reading, arithmetic and other cognitive functions (also briefly). Then I will ask you to let me know your thoughts about how we might improve our work.

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