Students need to take a total of at least 7 units from the following classes:
- GENE 203: Advanced Genetics (4 units)
For graduate students in Bioscience programs; may be appropriate for graduate students in other programs. The genetic toolbox. Examples of analytic methods, genetic manipulation, genome analysis, and human genetics. Emphasis is on use of genetic tools in dissecting complex biological pathways, developmental processes, and regulatory systems. Faculty-led discussion sections with evaluation of papers.
- BIOC 205: Molecular Foundations of Medicine (3 units)
Topics include DNA structure, replication, repair, and recombination; chromosome structure and function; gene expression including mechanisms for regulating transcription and translation; and methods for manipulating DNA, RNA, and proteins. Patient presentations illustrate how molecular biology affects the practice of medicine.
- INDE 220: Human Health and Disease I (3 units)
This course establishes the foundation for the Human Health and Disease block which spans the spring quarter of the first year medical curriculum through the winter quarter of year two.
- GENE 211: Genomics (3 units)
Genome evolution, organization, and function; technical, computational, and experimental approaches; hands-on experience with representative computational tools used in genome science; and a beginning working knowledge of PERL.
- GENE 210: Genomics and Personalized Medicine (2 units)
Student-initiated course. Principles of genetics underlying associations between genetic variants and disease susceptibility and drug response. Topics include: genetic and environmental risk factors for complex genetic disorders; design and interpretation of genome-wide association studies; pharmacogenetics; full genome sequencing for disease gene discovery; population structure and genetic ancestry; use of personal genetic information in clinical medicine; ethical, legal, and social issues with personal genetic testing. Hands-on workshop making use of personal or publically available genetic data.
Three of these suggested classes are required by the Masters of Medicine (MOM) program, which the Medical School opens to all University PhD students (with competitive admission). This is an opportunity that we encourage the trainees to consider. The Spectrum program for translational medicine may contribute funds to cover the extra tuition costs (relative to the second year of the MOM).