Clinical Trials
Open clinical studies originating from our work:
- · BP-U-004: Adoptive infusion of genetically modified T-cells with the suicide gene for the inducible Caspase9 (iC9) after alpha/beta T-cell depleted haploidentical stem cell transplant.
· PBMTC ONC1401: The Role of KIR-favorably Mismatched Haploidentical Transplantation and KIR-polymorphisms in Determining Outcomes of Children with ALL/AML/MDS Undergoing Allogeneic Hematopoietic Cell Transplantation
· A randomized trial of low versus moderate exposure busulfan for infants with severe combined immunodeficiency (SCID) receiving TCRαβ+/CD19+ depleted transplantation: A Phase II study by the Primary Immune Deficiency Treatment Consortium (PIDTC) and Pediatric Bone Marrow Transplant Consortium (PBMTC)
· Title: Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Young Adults
Brief Description: Phase II trial of allogeneic hematopoietic stem cell transplantation from an HLA-partially matched related or unrelated donor after TCR ab+ T cells/CD19+ B cell depletion in pediatric and young adult patients affected by malignant or non-malignant hematological disorders.