Selected Publications

  1. Zhao, Z., Abdolazimi, Y., Armstrong, N.A.Annes, J.P. 2016. A high-content in vitro pancreatic islet beta-cell replication screening platform. JOVE
  2. Zhao, Z., Low, Y.S., Armstrong, N.A., Ryu, J.H., Sun, S.A., Arvanites, A.C., Hollister-Lock, J., Shah, N.H., Weir, G.C., and Annes, J.P. 2014. Repurposing cAMP-modulating medications to promote beta-cellreplication. Mol Endocrinol 28:1682-1697.  
    *Selected by the Endocrine Society as THE BEST of BASIC RESEARCH 2014
  3. Nichols, R.J., New, C., and Annes, J.P. 2014. Adult tissue sources for new beta cells. Transl Res 163:418-431.
  4. Vaidya, A., Underwood, P.C., Annes, J.P., Sun, B., Williams, G.H., Forman, J.P., and Williams, J.S. 2013. The influence of sodium- and calcium-regulatory hormone interventions on adipocytokines in obesity and diabetes. Metabolism 62:539-547.
  5. Wei, K., Piecewicz, S.M., McGinnis, L.M., Taniguchi, C.M., Wiegand, S.J., Anderson, K., Chan, C.W., Mulligan, K.X., Kuo, D., Yuan, J., et al. 2013. A liver Hif-2alpha-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition. Nat Med 19:1331-1337.
  6. Chen, C.A., Carolan, P.C., and Annes, J.P. 2012. In vivo screening for secreted proteins that modulate glucose handling identifies interleukin-6 family members as potent hypoglycemic agents. PLoS One 7:e44600.
  7. Bar-Lev, A., and Annes, J.P. 2012. Genetics of adrenocortical disease: an update. Curr Opin Endocrinol Diabetes Obes 19:159-167.
  8. Annes, J.P., Ryu, J.H., Lam, K., Carolan, P.J., Utz, K., Hollister-Lock, J., Arvanites, A.C., Rubin, L.L., Weir, G., and Melton, D.A. 2012. Adenosine kinase inhibition selectively promotes rodent and porcine islet beta-cell replication. Proc Natl Acad Sci U S A 109:3915-3920.
  9. Volpicelli, E.R., Doyle, L., Annes, J.P., Murray, M.F., Jacobsen, E., Murphy, G.F., and Saavedra, A.P. 2011. Erdheim-Chester disease presenting with cutaneous involvement: a case report and literature review. J Cutan Pathol 38:280-285.
  10. Annes, J.P., Giovanni, M.A., and Murray, M.F. 2010. Risks of presymptomatic direct-to-consumer genetic testing. N Engl J Med 363:1100-1101.
  11. Annes, J.P., Chen, Y., Munger, J.S., and Rifkin, D.B. 2004. Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1. J Cell Biol 165:723-734.
  12. Annes, J., Vassallo, M., Munger, J.S., and Rifkin, D.B. 2004. A genetic screen to identify latent transforming growth factor beta activators. Anal Biochem 327:45-54.
  13. Krishnan, S., Deora, A.B., Annes, J.P., Osoria, J., Rifkin, D.B., and Hajjar, K.A. 2004. Annexin II-mediated plasmin generation activates TGF-beta3 during epithelial-mesenchymal transformation in the developing avian heart. Dev Biol 265:140-154.
  14. Annes, J.P., Munger, J.S., and Rifkin, D.B. 2003. Making sense of latent TGFbeta activation. J Cell Sci 116:217-224.
  15. Chen, Y., Dabovic, B., Annes, J.P., and Rifkin, D.B. 2002. Latent TGF-beta binding protein-3 (LTBP-3) requires binding to TGF-beta for secretion. FEBS Lett 517:277-280.
  16. Annes, J.P., Rifkin, D.B., and Munger, J.S. 2002. The integrin alphaVbeta6 binds and activates latent TGFbeta3. FEBS Lett 511:65-68.
  17. Gualandris, A., Annes, J.P., Arese, M., Noguera, I., Jurukovski, V., and Rifkin, D.B. 2000. The latent transforming growth factor-beta-binding protein-1 promotes in vitro differentiation of embryonic stem cells into endothelium. Mol Biol Cell 11:4295-4308.
  18. Sun, Z., Arendt, C.W., Ellmeier, W., Schaeffer, E.M., Sunshine, M.J., Gandhi, L., Annes, J., Petrzilka, D., Kupfer, A., Schwartzberg, P.L., et al. 2000. PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes. Nature 404:402-407.