Publications

Prostaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models
Johansson, J. U., Woodling, N. S., Wang, Q., Panchal, M., Hang, X., Trueba-Saiz, A., Brown, H. D., Mhatre, S. D., Loui, T., Andreasson, K. I. J Clin Invest. 2015; 125 (1): 350-364. doi: 10.1172/JCI77487

Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling.
Woodling NS, Wang Q, Priyam PG, Larkin P, Shi J, Johansson JU, Zagol-Ikapitte I, Boutaud O, Andreasson KI. J Neurosci. 2014 Apr 23;34(17):5882-94. doi: 10.1523/JNEUROSCI.0410-14.2014.

Suppression of inflammation with conditional deletion of the prostaglandin E2 EP2 receptor in macrophages and brain microglia.
Johansson JU, Pradhan S, Lokteva LA, Woodling NS, Ko N, Brown HD, Wang Q, Loh C, Cekanaviciute E, Buckwalter M, Manning-Bog AB, Andreasson KI. J Neurosci. 2013 Oct 2;33(40):16016-32. doi: 10.1523/JNEUROSCI.2203-13.2013.

Signaling via the prostaglandin E2 receptor EP4 exerts neuronal and vascular protection in a mouse model of cerebral ischemia.
Liang X, Lin L, Woodling NS, Wang Q, Anacker C, Pan T, Merchant M, Andreasson K. J Clin Invest. 2011; 121 (11): 4362-71

Emerging roles of PGE2 receptors in models of neurological disease.
Andreasson K, Prostaglandins Other Lipid Mediat. 2010; 91 (3-4): 104-12

The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity.
Shi J, Johansson J, Woodling NS, Wang Q, Montine TJ, Andreasson K. J Immunol. 2010; 184 (12): 7207-18

The prostaglandin E2 EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis.
Liang X, Wang Q, Shi J, Lokteva L, Breyer RM, Montine TJ, Andreasson K. Ann Neurol. 2008; 64 (3): 304-14

Cyclooxygenase-dependent lipid-modification of brain proteins.
Boutaud O, Andreasson KI, Zagol-Ikapitte I, Oates JA. Brain Pathol. 2005; 15 (2): 139-42

Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease.
Liang X, Wang Q, Hand T, Wu L, Breyer RM, Montine TJ, Andreasson K. J Neurosci. 2005; 25 (44): 10180-7

PGE2 receptors rescue motor neurons in a model of amyotrophic lateral sclerosis.
Bilak M, Wu L, Wang Q, Haughey N, Conant K, St Hillaire C, Andreasson K. Ann Neurol. 2004; 56 (2): 240-8

Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia.
McCullough L, Wu L, Haughey N, Liang X, Hand T, Wang Q, Breyer RM, Andreasson K. J Neurosci. 2004; 24 (1): 257-68

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