Recent Peer-Reviewed Research Publications
- Balz K, Kaushik A, Chen M, Cemic F, Heger V, Renz H, Nadeau K, Skevaki C. Homologies between SARS-CoV-2 and allergen proteins may direct T cell-mediated heterologous immune responses. Sci Rep. 2021 Feb 26;11(1):4792.
- Halken S, Muraro A, de Silva D, Khaleva E, Angier E, Arasi S, Arshad H, Bahnson H, Beyer K, Boyle R, du Toit G, Ebisawa M, Eigenmann P, Grimshaw K, Hoest A, Jones C, Lack G, Nadeau K, O’Mahony L, Szajewska H, Venter C, Verhasselt V, Wong G, Roberts on behalf of European Academy of Allergy and Clinical Immunology Food Allergy and Anaphylaxis Guidelines Group. EAACI guideline: preventing the development of food allergy in infants and young children (2020 update). Pediatr Allergy Immunol. Accepted Feb 26, 2021. In Press.
- Skevaki C, Karsonova A, Karaulov A, Fomina D, Xie M, Chinthrajah S, Nadeau KC, Renz H. SARS-CoV-2 infection and COVID-19 in asthmatics: a complex relationship. Nat Rev Immunol. 2021 Feb 23:1–2. [Epub ahead of print].
- Sweeney A, Sampath V, Nadeau KC. Early intervention of atopic dermatitis as a prevention strategy for preogression to food allergy. Allergy, Asthma, and Clinical Immunology. Accepted February 21,2021. In Press.
- Nygaard UC, Xiao L, Nadeau KC, Hew KM, Lv N, Camargo CA Jr., Strub P, Ma J. Improved diet quality is associated with decreased levels of inflammatory markers in adults with uncontrolled asthma. Am. J. Clin. Nutr. Accepted Feb 19, 2021. In Press.
- Prunicki M, Cauwenberghs N, Lee J, Zhou X, Movassagh H, Noth E, Lurmann F, Hammond SK, Balmes JR, Desai M, Wu JC, Nadeau KC. Air pollution exposure is linked with methylation of immunoregulatory genes, altered immune cell profiles, and increased blood pressure in children. Sci Rep. 2021 Feb 18;11(1):4067.
- Sahiner UM, Layhadi JA, Golebski K, István Komlósi Z, Peng Y, Sekerel B, Durham SR, Brough H, Morita H, Akdis M, Turner P, Nadeau K, Spits H, Akdis C, Shamji MH. Innate Lymphoid Cells: The Missing Part Of A Puzzle In Food Allergy. Allergy. 2021 Feb 14. [Epub ahead of print].
- Mann JK, Lutzker L, Holm SM, Margolis HG, Neophytou AM, Eisen EA, Costello S, Tyner T, Holland N, Tindula G, Prunicki M, Nadeau K, Noth EM, Lurmann F, Hammond SK, Balmes JR. Traffic-related Air Pollution is Associated with Glucose Dysregulation, Blood Pressure, and Oxidative Stress in Children. Environ Res. 2021 Feb 12:110870.
- Zhou X, Han X, Lyu SC, Bunning BJ, Kost L, Chang I, Cao S, Sampath V, Nadeau KC. Targeted DNA methylation profiling reveals epigenetic signatures in peanut allergy. JCI Insight. 2021 Feb 11:143058.
- Patel N, Adelman DC, Anagnostou K, Baumert JL, Blom WM, Campbell DE, Chinthrajah RS, Mills ENC, Javed B, Purington N, Remington BC, Sampson HA, Smith AD, Yarham RAR, Turner PJ. Using data from food challenges to inform management of food-allergic consumers: a systematic review with individual participant data meta-analysis. J Allergy Clin Immunol. 2021 Feb 9. [Epub ahead of print].
- Warren C, Lei D, Sicherer S, Schleimer R, Gupta R. Prevalence and characteristics of peanut allergy in US adults. J Allergy Clin Immunol. 2021 Feb 3. [Epub ahead of print].
- Nygaard UC, Xiao L, Nadeau KC, Hew KM, Lv N, Camargo CA Jr., Strub P, Ma J. Improved diet quality is associated with decreased levels of inflammatory markers in adults with uncontrolled asthma. Am. J. Clin. Nutr. Accepted Feb 8, 2021. In Press.
- Huang Y, Radenkovic D, Perez K, Nadeau K, Verdin E, Furman D. COVID-19 Patients Seeking Treatment: Modeling Predictive Age-dependent and Independent Symptoms and Comorbidities. J Med Internet Res. 2021 Feb 8. [Epub ahead of print].
- Wanet A, Bassal MA, Patel SB, Marchi F, Mariani SA, Ahmed N, Zhang H, Borchiellini M, Chen S, Zhang J, Di Ruscio A, Miyake K, Tsai M, Paranjape A, Park SY, Karasuyama H, Schroeder T, Dzierzak E, Galli SJ, Tenen DG, Welner RS. E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates. Sci Immunol. 2021 Feb 5;6(56):eaba0178.
- Hedlin H, Garcia A, Weng Y, He Z, Sundaram V, Bunning B, Balasubramanian V, Cunanan K, Kapphahn K, Gummidipundi S, Purington N, Boulos M, Desai M. Clinical trials in a COVID-19 pandemic: Shared infrastructure for continuous learning in a rapidly changing landscape. Clin Trials. 2021 Feb 3 [Epub ahead of print]
- Lopez-Lopez C, Jaramillo-Polanco J, Talavera K, Alpizar YA, Feyerabend TB, Rodewald HR, Farre R, Redegeld FA, Si J, Raes J, Breynaert C, Schrijvers R, Bosteels C, Lambrecht BN, Boyd SD, Hoh RA, Cabooter D, Nelis M, Augustijns P, Hendrix S, Strid J, Bisschops R, Reed DE, Vanner SJ, Denadai-Souza A, Wouters MM, Boeckxstaens GE. Local immune response to food antigens drives meal-induced abdominal pain. Nature. 2021 Feb;590(7844):151-156.
- Yan Z, Maecker HT, Brodin P, Nygaard UC, Lyu SC, Davis MM, Nadeau KC, Andorf S. Aging and CMV discordance are associated with increased immune diversity between monozygotic twins. Immun Ageing. 2021 Jan 18;18(1):5.
- Sokolowska M, Eiwegger T, Ollert M, Torres MJ, Barber D, Del Giacco S, Jutel M, Nadeau KC, Palomares O, Rabin RL, Riggioni C, Vieths S, Agache I, Shamji MH. EAACI statement on the diagnosis, management and prevention of severe allergic reactions to COVID-19 vaccines. Allergy. 2021 Jan 16. [ Epub ahead of print].
- Gupta RS, Fierstein JL, Boon KL, Kanaley MK, Bozen A, Kan K, Vojta D, Warren CM. Sensor-Based Electronic Monitoring for Asthma: A Randomized Controlled Trial. Pediatrics. 2021 Jan;147(1):e20201330.
- Turner-Bowker DM, Jalbert JJ, Krohe M, Yaworsky A, Kelly MT, Padilla B, Chaston E, Radin A, Mastey V, Nadeau KC. A novel patient-reported outcomes instrument assessing the side effects of peanut oral immunotherapy. Ann Allergy Asthma Immunol. 2021 Jan;126(1):61-68.
- Chakraborty S, Gonzalez J, Edwards K, Mallajosyula V, Buzzanco AS, Sherwood R, Buffone C, Kathale N, Providenza S, Xie MM, Andrews JR, Blish CA, Singh U, Dugan H, Wilson PC, Pham TD, Boyd SD, Nadeau KC, Pinsky BA, Zhang S, Memoli MJ, Taubenberger JK, Morales T, Schapiro JM, Tan GS, Jagannathan P, Wang TT. Proinflammatory IgG Fc structures in patients with severe COVID-19. Nat Immunol. 2021 Jan;22(1):67-73.
- Yu W, Zhou X, Lyu SC, Davis MM, Nadeau KC. Regulation of peanut-specific CD8+ T cells from nonallergic individuals. J Allergy Clin Immunol. 2021 Jan;147(1):385-387.
- Neeland MR, Tursi AR, Perrett KP, Saffery R, Koplin JJ, Nadeau KC, Andorf S. Vitamin D insufficiency is associated with reduced regulatory T cell frequency in food-allergic infants. Pediatr Allergy Immunol. 2020 Dec 22. [Epub ahead of print].
- Arasi S, Nurmatov U, Turner PJ, Ansotegui IJ, Daher S, Dunn-Galvin A, Ebisawa M, Eigenmann P, Fernandez-Rivas M, Gupta R, Nowak-Wegrzyn A, Petrou S, Roberts G, Sánchez Borges MA, Sindher SB, Tanno LK, Vazquez-Ortiz M, Vickery BP, Wong GW, Fiocchi A. Consensus on DEfinition of Food Allergy SEverity (DEFASE): Protocol for a systematic review. World Allergy Organ J. 2020 Dec 19;13(12):100493.
- Paranjape A, Tsai M, Mukai K, Hoh RA, Joshi SA, Chinthrajah RS, Nadeau KC, Boyd SD, Galli SJ. Oral Immunotherapy and Basophil and Mast Cell Reactivity in Food Allergy. Front Immunol. 2020 Dec 14;11:602660.
- Kalil AC, Patterson TF, Mehta AK, Tomashek KM, Wolfe CR, Ghazaryan V, Marconi VC, Ruiz-Palacios GM, Hsieh L, Kline S, Tapson V, Iovine NM, Jain MK, Sweeney DA, El Sahly HM, Branche AR, Regalado Pineda J, Lye DC, Sandkovsky U, Luetkemeyer AF, Cohen SH, Finberg RW, Jackson PEH, Taiwo B, Paules CI, Arguinchona H, Goepfert P, Ahuja N, Frank M, Oh MD, Kim ES, Tan SY, Mularski RA, Nielsen H, Ponce PO, Taylor BS, Larson L, Rouphael NG, Saklawi Y, Cantos VD, Ko ER, Engemann JJ, Amin AN, Watanabe M, Billings J, Elie MC, Davey RT, Burgess TH, Ferreira J, Green M, Makowski M, Cardoso A, de Bono S, Bonnett T, Proschan M, Deye GA, Dempsey W, Nayak SU, Dodd LE, Beigel JH. Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19. N Engl J Med. 2020 Dec 11. [Epub ahead of print]
- Duan L, Celik A, Hoang JA, Schmidthaler K, So D, Yin X, Ditlof CM, Ponce M, Upton JEM, Lee JS, Hung L, Breiteneder H, Palladino C, Atkinson AR, Kim VHD, Berenjy A, Asper M, Hummel D, Wong S, Alexanian-Farr M, Magder A, Chinthrajah SR, Mukai K, Tsai M, Nadeau K, Galli SJ, Ramani AK, Szepfalusi Z, Eiwegger T. Basophil activation test shows high accuracy in the diagnosis of peanut and tree nut allergy: The Markers of Nut Allergy Study. Allergy. 2020 Dec 9. [Epub ahead of print].
- Roltgen K, Powell AE, Wirz OF, Stevens BA, Hogan CA, Najeeb J, Hunter M, Wang H, Sahoo MK, Huang C, Yamamoto F, Manohar M, Manalac J, Otrelo-Cardoso AR, Pham TD, Rustagi A, Rogers AJ, Shah NH, Blish CA, Cochran JR, Jardetzky TS, Zehnder JL, Wang TT, Narasimhan B, Gombar S, Tibshirani R, Nadeau KC, Kim PS, Pinsky BA, Boyd SD. Defining the features and duration of antibody responses to SARS-CoV-2 infection associated with disease severity and outcome. Sci Immunol. 2020 Dec 7;5(54):eabe0240.
- Satitsuksanoa P, Daanje M, Akdis M, Boyd SD, van de Veen W. Biology and dynamics of B cells in the context of IgE-mediated food allergy. Allergy. 2020 Dec 3. [Epub ahead of print].
- Baker N, Bromley-Dulfano R, Chan J, Gupta A, Herman L, Jain N, Taylor AL, Lu J, Pannu J, Patel L, Prunicki M. COVID-19 Solutions Are Climate Solutions: Lessons From Reusable Gowns. Front Public Health. 2020 Nov 25;8:590275.
- Goshua A, Gomez J, Erny B, Burke M, Luby S, Sokolow S, LaBeaud AD, Auerbach P, Gisondi MA, Nadeau K. Addressing Climate Change and Its Effects on Human Health: A Call to Action for Medical Schools. Acad Med. 2020 Nov 24. [Epub ahead of print].
- Pham TD, Huang C, Wirz OF, Röltgen K, Sahoo MK, Layon A, Pandey S, Foung SK, Boyd SD, Pinsky BA. SARS-CoV-2 RNAemia in a Healthy Blood Donor 40 Days After Respiratory Illness Resolution. Ann Intern Med. 2020 Nov 17;173(10):853-854.
- Gonzalez NV, Oliveria JP, Tebaykin D, Ivison GT, Mukai K, Tsai MM, Borges L, Nadeau KC, Galli SJ, Tsai AG, Bendall SC. Mass cytometry phenotyping of human granulocytes reveals novel basophil functional heterogeneity. iScience. 2020 Nov 20;23(11):101724.
- Wawrzyniak P, Krawczyk K, Swati A, Tan G, Wawrzyniak M, Karouzakis E, Dreher A, Jakiela B, Altunbulakli C, Sanak M, O'Mahony L, Nadeau K, and Akdis C. Inhibition of CpG methylation improves the barrier integrity of bronchial epithelial cells in asthma. Allergy. 2020 Nov 19. [Epub ahead of print].
- Dreskin SC, Koppelman S, Andorf S, Nadeau KC, Kalra A, Braun W, Negi SS, Chen X, Schein CH. The importance of the 2S albumins for allergenicity and cross-reactivity of peanuts, tree nuts and sesame seeds. J Allergy Clin Immunol. 2020 Nov 17. [Epub ahead of print].
- Beigel JH, Tomashek KM, Dodd LE and ACTT-1 Study Group Members (K Nadeau - middle author). Remdesivir for the Treatment of Covid-19 - Final Report. N Engl J Med. Nov 5;383(19):1813-1826.
- Sharif H, Acharya S, Dhondalay GKR, Varricchi G, Krasner-Macleod S, Laisuan W, Zhang J, Switzer A, Lenormand M, Kashe E, Parkin RV, Yi Y, Koc M, Fedina O, Vilà-Nadal G, Marone G, Eifan A, Scadding G, Fear D, Nadeau KC, Durham SR, Shamji MH. Grass pollen immunotherapy alters chromatin landscape in circulating T follicular and regulatory cells. J Allergy Clin Immunol. J Allergy Clin Immunol. 2020 Nov 5 [Epub ahead of print].
- Radzikowska U, Ding M, Tan G, Zhakparov D, Peng Y, Wawrzyniak P, Wang M, Li S, Morita H, Altunbulakli C, Reiger M, Neumann AU, Lunjani N, Traidl-Hoffmann C, Nadeau K, O'Mahony L, Akdis CA, Sokolowska M. Distribution of ACE2, CD147, CD26 and other SARS-CoV-2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID-19 risk factors. Allergy. 2020 Nov;75(11):2829-2845.
- Goyard S, Balbino B, Chinthrajah RS, Lyu SC, Janin YL, Bruhns P, Poncet P, Galli SJ, Nadeau KC, Reber LL, Rose T. A highly sensitive bioluminescent method for measuring allergen-specific IgE in microliter samples. Allergy. 2020 Nov;75(11):2952-2956.
- Krempski JW, Dant C, Nadeau KC. The Origins of Allergy from a Systems Approach. Ann Allergy Asthma Immunol. 2020 Nov;125(5):507-516.
- Steffes LC, Froistad AA, Andruska A, Boehm M, McGlynn M, Zhang F, Zhang W, Hou D, Tian X, Miquerol L, Nadeau K, Metzger RJ, Spiekerkoetter E, Kumar ME. A Notch3-Marked Subpopulation of Vascular Smooth Muscle Cells is the Cell of Origin for Occlusive Pulmonary Vascular Lesions. Circulation. 2020 Oct 20;142(16):1545-1561.
- Bao R, Hesser LA, He Z, Zhou X, Nadeau KC*, Nagler CR*. Fecal microbiome and metabolome differ in healthy and food-allergic twins. J Clin Invest. Accepted Oct 21, 2020. In Press. (co-senior authors)
- Han X, Krempski JW, Nadeau K. Advances and novel developments in mechanisms of allergic inflammation. Allergy. 2020 Oct 17. [Epub ahead of print].
- Prunicki M, Cauwenberghs N, Ataam JA, Movassagh H, Kim JB, Kuznetsova T, Wu JC, Maecker H, Haddad F, Nadeau K. Immune biomarkers link air pollution exposure to blood pressure in adolescents. Environ Health. 2020 Oct 16;19(1):108.
- Starkl P, Watzenboeck ML, Popov LM, Zahalka S, Hladik A, Lakovits K, Radhouani M, Haschemi A, Marichal T, Reber LL, Gaudenzio N, Sibilano R, Stulik L, Fontaine F, Mueller AC, Amieva MR, Galli SJ, Knapp S. IgE Effector Mechanisms, in Concert with Mast Cells, Contribute to Acquired Host Defense against Staphylococcusaureus. Immunity. 2020 Oct 13;53(4):793-804.e9.
- Alkotob SS, Cannedy C, Harter K, Movassagh H, Paudel B, Prunicki M, Sampath V, Schikowski T, Smith E, Zhao Q, Traidl-Hoffmann C, Nadeau KC. Advances and novel developments in environmental influences on the development of atopic diseases. Allergy. 2020 Oct 9. [Epub ahead of print].
- Nielsen SCA, Yang F, Jackson KJL, Hoh RA, Röltgen K, Jean GH, Stevens BA, Lee JY, Rustagi A, Rogers AJ, Powell AE, Hunter M, Najeeb J, Otrelo-Cardoso AR, Yost KE, Daniel B, Nadeau KC, Chang HY, Satpathy AT, Jardetzky TS, Kim PS, Wang TT, Pinsky BA, Blish CA, Boyd SD. Human B Cell Clonal Expansion and Convergent Antibody Responses to SARS-CoV-2. Cell Host Microbe. 2020 Oct 7;28(4):516-525.
- Kabasser S, Hafner C, Chinthrajah S, Sindher SB, Kumar D, Kost LE, Long AJ, Nadeau KC, Breiteneder H, Bublin M. Identification of Pru du 6 as a potential marker allergen for almond allergy. Allergy. 2020 Oct 6. [Epub ahead of print].
- Sindher S, Alkotob SS, Shojinaga MN, Brough HA, Bahnson T, S C, Lack G, Leung DYM, Nadeau KC. Pilot study measuring transepidermal water loss (TEWL) in children suggests trilipid cream is more effective than a paraffin-based emollient. Allergy. 2020 Oct;75(10):2662-2664.
- Riggioni C, Comberiati P, Giovannini M, Agache I, Akdis M, Alves-Correia M, Antó JM, Arcolaci A, Kursat Azkur A, Azkur D, Beken B, Boccabella C, Bousquet J, Breiteneder H, Carvalho D, De Las Vecillas L, Diamant Z, Eguiluz-Gracia I, Eiwegger T, Eyerich S, Fokkens W, Gao YD, Hannachi F, Johnston SL, Jutel M, Karavelia A, Klimek L, Moya B, Nadeau K, O'Hehir R, O'Mahony L, Pfaar O, Sanak M, Schwarze J, Sokolowska M, Torres MJ, van de Veen W, van Zelm MC, Wang Y, Zhang L, Jiménez-Saiz R, Akdis CA. A compendium answering 150 questions on COVID-19 and SARS-CoV-2. Allergy. 2020 Oct;75(10):2503-2541.
- Wang W, Lyu SC, Ji X, Gupta S, Manohar M, Dhondalay GKR, Chinthrajah S, Andorf S, Boyd SD, Tibshirani R, Galli SJ, Nadeau KC, Maecker HT. Transcriptional changes in peanut-specific CD4+ T cells over the course of oral immunotherapy. Clin Immunol. 2020 Oct;219:108568.
- Sokolowska M, Lukasik Z, Agache I, Akdis CA, Akdis D, Akdis M, Barcik W, Brough H, Eiwegger T, Eliaszewicz A, Eyerich S, Feleszko W, Gomez Casado C, Hoffmann-Sommergruber K, Janda J, Jiménez-Saiz R, Jutel M, Knol E, Kortekaas Krohn I, Kothari A, Makowska J, Moniuszko M, Morita H, O'Mahony L, Nadeau K, Ozdemir C, Pali-Schöll I, Palomares O, Papaleo F, Prunicki M, Schmidt-Weber CB, Sediva A, Schwarze J, Shamji MH, Tramper-Stranders G, van W, de Veen, Untersmayr E. Immunology of COVID-19: mechanisms, clinical outcome, diagnostics and perspectives - a report of the European Academy of Allergy and Clinical Immunology (EAACI). Allergy. 2020 Oct;75(10):2445-2476.
- Galic I, Warren CM, Jiang J, Tobin MC, Gupta RS. Parent report of physician diagnosis in pediatric food allergy: An update. J Allergy Clin Immunol Pract. 2020 Sep 30. [Epub ahead of print].
- Chinthrajah RS, Cao S, Dunham T, Sampath V, Chandra S, Chen M, Sindher S, Nadeau K. Oral immunotherapy for peanut allergy: The pro argument. World Allergy Organ J. 2020 Sep 18;13(8):100455.
- Breiteneder H, Peng YQ, Agache I, Diamant Z, Eiwegger T, Fokkens WJ, Traidl-Hoffmann C, Nadeau K, O'Hehir RE, O'Mahony L, Pfaar O, Torres MJ, Wang DY, Zhang L, Akdis CA. Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma. Allergy. 2020 Sep 7. [Epub ahead of print].
- Prunicki MM, Dant CC, Cao S, Maecker H, Haddad F, Kim JB, Snyder M, Wu J, Nadeau K. Immunologic effects of forest fire exposure show increases in IL-1β and CRP. Allergy. 2020 Sep;75(9):2356-2358.
- Brough HA, Nadeau KC, Sindher SB, Alkotob SS, Chan S, Bahnson H, Leung DYM, Lack G. Epicutaneous sensitization in the development of food allergy: what is the evidence and how can this be prevented? Allergy. 2020 Sep;75(9):2185-2205. (*: joint first authors, ** joint last authors).
- Bozen A, Zaslavsky JM, Cohn D, Samady W, Lombard L, Nadeau K, Tobin M, Warren CM, Gupta RS. Barriers to food allergy management among Americans with low income. Ann Allergy Asthma Immunol. 2020 Sep;125(3):341-343.
- Asai Y, Martino D, Eiwegger T, Nadeau K, Koppelman GH, Clarke AE, Lee YA, Chan ES, Simons E, Laprise C, Mazer B, Marenholz I, Royce D, Elliott SJ, Hampson C, Gerdts J, Eslami A, Soller L, Hui J, Azad M, Sandford A, Daley D. Phenotype consensus is required to enable large-scale genetic consortium studies of food allergy. Allergy. 2020 Sep;75(9):2383-2387.
- Diffenbaugh NS, Field CB, Appel EA, Azevedo IL, Baldocchi DD, Burke M , Burney JA , Ciais P, Davis SJ, Fiore AM, Fletcher SM, Hertel TW, Horton DE, Hsiang SM , Jackson RB, Jin X, Levi M, Lobell DB, McKinley GA, Moore FC, Montgomery A, Nadeau KC, Pataki DE, Randerson JT, Reichstein M, Schnell JL, Seneviratne SI , Singh D, Steiner AL, Wong-Parodi G. The COVID-19 lockdowns: a window into the Earth System. Nat Rev Earth Environ. 2020 Sep;1:470-481.
- Valent P, Akin C, Hartmann K, Nilsson G, Reiter A, Hermine O, Sotlar K, Sperr WR, Escribano L, George TI, Kluin-Nelemans HC, Ustun C, Triggiani M, Brockow K, Gotlib J, Orfao A, Kovanen PT, Hadzijusufovic E, Sadovnik I, Horny HP, Arock M, Schwartz LB, Austen KF, Metcalfe DD, Galli SJ. Mast cells as a unique hematopoietic lineage and cell system: From Paul Ehrlich's visions to precision medicine concepts. Theranostics. 2020 Aug 29;10(23):10743-10768.
- Oyoshi M, Chinthrajah RS. Editorial: Insights Into the Etiology, Prevention, and Treatment of Food Allergy. Front Immunol. 2020 Aug 21;11:1937.
- He Z, Vadali VG, Szabady RL, Zhang W, Norman JM, Roberts B, Tibshirani R, Desai M, Chinthrajah RS, Galli SJ, Andorf S, Nadeau KC. Increased diversity of gut microbiota during active oral immunotherapy in peanut allergic adults. Allergy. 2020 Aug 4. [Epub ahead of print].
- Sindher S, Alkotob SS, Shojinaga MN, Hamilton R, Chan S, Cao S, Bahnson HT, Brough HA, Lack G, Leung DYM, Nadeau KC. Increases in plasma IgG4/IgE with trilipid vs paraffin/petrolatum-based emollients for dry skin/eczema. Pediatr Allergy Immunol. 2020 Aug;31(6):699-703.
- He Z, Dongre P, Lyu SC, Manohar M, Chinthrajah RS, Galli SJ, DeKruyff RH, Nadeau KC, Andorf S. Identification of cross-reactive allergens in cashew- and pistachio-allergic children during oral immunotherapy. Pediatr Allergy Immunol. 2020 Aug;31(6):709-714.
- Sonnet F, Namork E, Stylianou E, Gaare-Olstad I, Huse K, Andorf S, Mjaaland S, Dirven H, Nygaard U. Reduced polyfunctional T cells and increased cellular activation markers in adult allergy patients reporting adverse reactions to food. BMC Immunol. 2020 Jul 22;21(1):43.
- Pham TD, Huang C, Wirz OF, Röltgen K, Sahoo MK, Layon A, Pandey S, Foung SK, Boyd SD, Pinsky BA. SARS-CoV-2 RNAemia in a Healthy Blood Donor 40 Days After Respiratory Illness Resolution. Ann Intern Med. 2020 Jul 17. [Epub ahead of print.]
- Azkur AK, Akdis M, Azkur D, Sokolowska M, van de Veen W, Brüggen MC, O'Mahony L, Gao Y, Nadeau K, Akdis CA. Immune response to SARS-CoV-2 and mechanisms of immunopathological changes in COVID-19. Allergy. 2020 Jul;75(7):1564-1581.
- Fleischer DM, Shreffler WG, Campbell DE, Green TD, Anvari S, Assa'ad A, Bégin P, Beyer K, Bird JA, Brown-Whitehorn T, Byrne A, Chan ES, Cheema A, Chinthrajah S, Chong H, Davis CM, Ford LS, Gagnon R, Greenhawt M, O'B Hourihane J, Jones SM, Kim EH, Lange L, Lanser BJ, Leonard S, Mahler V, Maronna A, Nowak-Wegrzyn A, Oriel RC, O'Sullivan M, Petroni D, Pongracic JA, Prescott SL, Schneider LC, Smith P, Staab D, Sussman G, Wood R, Yang WH, Lambert R, Peillon A, Bois T, Sampson HA. Long-Term, Open-Label Extension Study of the Efficacy and Safety of Epicutaneous Immunotherapy for Peanut Allergy in Children: PEOPLE 3-Year Results. J Allergy Clin Immunol. 2020 Jul. [Epub ahead of print].
- Bousquet J, Jutel M, Akdis CA, Klimek L, Pfaar O, Nadeau KC, Eiwegger T, Bedbrook A, Ansotegui IJ, Anto JM, Bachert C, Bateman ED, Bennoor KS, Berghea EC, Bergmann KC, Blain H, Bonini M, Bosnic-Anticevich S, Boulet LP, Brussino L, Buhl R, Camargos P, Canonica GW, Cardona V, Casale T, Chinthrajah S, Akdis M, Chivato T, Christoff G, Cruz AA, Czarlewski W, Del Giacco S, Du H, El-Gamal Y, Fokkens WJ, Fonseca JA, Gao Y, Gaga M, Gemicioglu B, Gotua M, Haahtela T, Halpin D, Hamelmann E, Hoffmann-Sommergruber K, Humbert M, Ilina N, Ivancevich JC, Joos G, Khaitov M, Kirenga B, Knol EF, Ko FW, Koskinen S, Kowalski ML, Kraxner H, Kudlay D, Kuna P, Kupczyk M, Kvedariene V, Abdul Latiff AH, Le LT, Levin M, Larenas-Linnemann D, Louis R, Masjedi MR, Melén E, Mihaltan F, Milenkovic B, Mohammad Y, Morais-Almeida M, Mullol J, Namazova L, Neffen H, Nunes E, O'Byrne P, O'Hehir R, O'Mahony L, Ohta K, Okamoto Y, Onorato GL, Panzner P, Papadopoulos NG, Passalacqua G, Patella V, Pawankar R, Pham-Thi N, Pigearias B, Popov TA, Puggioni F, Regateiro FS, Rolla G, Rottem M, Samolinski B, Sastre J, Schwarze J, Sheikh A, Scichilone N, Soto-Quiros M, Sova M, Nicola S, Stelmach R, Suppli-Ulrik C, Taborda-Barata L, To T, Tomazic PV, Toppila-Salmi S, Tsiligianni I, Usmani O, Valiulis A, Ventura MT, Viegi G, Vontetsianos T, Wang Y, Williams S, Wong GW, Yorgancioglu A, Zernotti M, Zidarn M, Zuberbier T, Agache I. ARIA-EAACI statement on Asthma and COVID-19 (June 2, 2020). Allergy. 2020 Jun 26. [Epub ahead of Print].
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- Rice MB, Malea NM, Pinkerton KE, Schwartz J, Nadeau KC, Browner CM, Whitehouse S, Thurston GD. Realizing the Paris Climate Agreement to Improve Cardiopulmonary Health: Where Science Meets Policy. Ann Am Thorac Soc. 2018 Jul;15(7):791-798.
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- Gaudenzio N, Marichal T, Galli SJ, Reber LL. Genetic and Imaging Approaches Reveal Pro-Inflammatory and Immunoregulatory Roles of Mast Cells in Contact Hypersensitivity. Front Immunol. 2018 Jun 5;9:1275.
- Zhang W, Lin C, Sampath V, Nadeau K. Impact of allergen immunotherapy in allergic asthma. Immunotherapy. 2018 Jun;10(7):579-593.
- Tsai CT, Mukai K, Robinson PV, Gray MA, Waschmann MB, Lyu SC, Tsai M, Chinthrajah RS, Nadeau KC, Bertozzi CR, Galli SJ. Isotype-Specific Agglutination- PCR (ISAP): a sensitive and multiplex method for measuring allergen-specific IgE. J Allergy Clin Immunol. 2018 May;141(5):1901-1904.e15.
- Pajno GB, Fernandez-Rivas M, Arasi S, Roberts G, Akdis CA, Alvaro-Lozano M, Beyer K, Bindslev-Jensen C, Burks W, Ebisawa M, Eigenmann P, Knol E, Nadeau KC, Poulsen LK, van Ree R, Santos AF, du Toit G, Dhami S, Nurmatov U, Boloh Y, Makela M, O'Mahony L, Papadopoulos N, Sackesen C, Agache I, Angier E, Halken S, Jutel M, Lau S, Pfaar O, Ryan D, Sturm G, Varga EM, van Wijk RG, Sheikh A, Muraro A; EAACI Allergen Immunotherapy Guidelines Group. EAACI Guidelines on allergen immunotherapy: IgE-mediated food allergy. Allergy. 2018 Apr;73(4):799-815.
- Sampath V, Sindher SB, Zhang W, Nadeau KC. New Treatment Directions in Food Allergy. Ann Allergy Asthma Immunol. 2018 Mar;120(3):254-262.
- Mukai K, Tsai M, Saito H, Galli SJ. Mast cells as sources of cytokines, chemokines, and growth factors. Immunol Rev. 2018 Mar;282(1):121-150.
- Andorf S, Purington N, Block WM, Long AJ, Tupa D, Brittain E, Spergel AR, Desai M, Galli SJ, Nadeau KC, Chinthrajah RS. Anti-IgE treatment with oral immunotherapy in multifood allergic participants: a double-blind, randomised, controlled trial. Lancet Gastroenterol Hepatol. 2018 Feb;3(2):85-94.
- Prunicki M, Stell L, Dinakarpandian D, De Planell-Saguerd M, Lucas RW, Hammond SK, Balmes JR, Zhou X, Paglino T, Sabatti C, Miller RL, Nadeau KC. Exposure to NO2, CO, and PM2.5 Is Linked to Regional DNA Methylation Differences in Asthma. Clin Epigenetics. 2018 Jan 5;10:2.
- Dhondalay GK, Rael E, Acharya, S, Zhang W, Sampath V, Galli SJ, Tibshirani, R, Boyd SD, Maecker, H, Nadeau KC, Andorf S. Food allergy and omics. J Allergy Clin Immunol. 2018 Jan;141:20-29.
- Pellerin L, Jenks JA, Chinthrajah S, Dominguez T, Block W, Zhou X, Noshirvan A, Gregori S, Roncarolo MG, Nadeau KC, Bacchetta R. Peanut-specific Tr1 cells induced in vitro from allergic individuals are functionally impaired. J Allergy Clin Immunol. 2018 Jan;141(1):202-213.e8.
- Galli SJ, Gaudenzio N. Human mast cells as antigen-presenting cells: when is this role important in vivo? J Allergy Clin Immunol. 2018 Jan;141(1):92-93.
- Tam IYS, Ng CW, Lau HYA, Tam SY. Degradation of Monocyte Chemoattractant Protein-1 by Tryptase Co-Released in Immunoglobulin E-Dependent Activation of Primary Human Cultured Mast Cells. Int Arch Allergy Immunol. 2018;177(3):199-206.
- Andorf S, Manohar M, Dominguez T, Block W, Tupa D, Kshirsagar RA, Sampath V,Chinthrajah RS, Nadeau KC. Feasibility of sustained response through long-term dosing in food allergy immunotherapy. Allergy Asthma Clin Immunol. 2017 Dec 21;13:52.
- Andorf S, Manohar M, Dominguez T, Block W, Tupa D, Kshirsagar RA, Sampath V, Chinthrajah RS, Nadeau KC. Observational long-term follow-up study of rapid food oral immunotherapy with omalizumab. Allergy Asthma Clin Immunol. 2017 Dec 21;13:51.
- Klein O, Roded A, Zur N, Azouz NP, Pasternak O, Hirschberg K, Hammel I, Roche PA, Yatsu A, Fukuda M, Galli SJ, Sagi-Eisenberg R. Rab5 is critical for SNAP23 regulated granule-granule fusion during compound exocytosis. Sci Rep. 2017 Nov 10;7(1):15315.
- Sampson HA, Shreffler WG, Yang WH, Sussman GL, Brown-Whitehorn TF, Nadeau KC, Cheema AS, Leonard SA, Pongracic JA, Sauvage-Delebarre C, Assa'ad AH, de Blay F, Bird JA, Tilles SA, Boralevi F, Bourrier T, Hébert J, Green TD, Gerth van Wijk R, Knulst AC, Kanny G, Schneider LC, Kowalski ML, Dupont C. Effect of Varying Doses of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Exposure Among Patients With Peanut Sensitivity: A Randomized Clinical Trial. JAMA. 2017 Nov 14;318(18):1798-1809.
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- Elizur A, Bollyky JB, Block WM. Elimination diet and the development of multiple tree-nut allergies. Pediatr Res. 2017 Oct;82(4):671-677
- Frischmeyer-Guerrerio PA, Masilamani M, Gu W, Brittain E, Wood R, Kim J, Nadeau K, Jarvinen KM, Grishin A, Lindblad R, Sampson HA. Mechanistic Correlates of Clinical Responses to Omalizumab in the Setting of Oral Immunotherapy for Milk Allergy. J Allergy Clin Immunol. 2017 Oct;140(4):1043-1053.e8.
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- Boyd SD, Hoh RA, Nadeau KC, Galli SJ. Immune monitoring for precision medicine in allergy and asthma. Curr Opin Immunol. 2017 Sep 6;48:82-91.
- Reber LL, Hernandez JD, Galli SJ. The pathophysiology of anaphylaxis. J Allergy Clin Immunol. 2017 Aug;140(2):335-348.
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- Chang HY, Nadeau KC. IL-4Rα Inhibitor for Atopic Disease. Cell. 2017 Jul 13;170(2):222.
- Muraro A, Lemanske RF Jr, Castells M, Torres MJ, Khan D, Simon HU, Bindslev-Jensen C, Burks W, Poulsen LK, Sampson HA, Worm M, Nadeau KC. Precision Medicine in Allergic Disease - Food Allergy, Drug Allergy, and Anaphylaxis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. Allergy. 2017 Jul;72(7):1006-1021.
- Nygaard UC, Li Z, Palys T, Jackson B, Subbiah M, Malipatlolla M, Sampath V, Maecker H, Karagas MR, Nadeau KC. Cord blood T cell subpopulations and associations with maternal cadmium and arsenic exposures. PLoS One. 2017 Jun 29;12(6):e0179606.
- Park HK, Cheng KC, Tetteh AO, Hildemann LM, Nadeau KC. Effectiveness of Air Purifier on Health Outcomes and Indoor Particles in Homes of Children with Allergic Diseases in Fresno: A Pilot Study. J Asthma. 2017 May;54(4):341-346.
- Galli SJ. Mast Cells and KIT as Potential Therapeutic Targets in Severe Asthma. N Engl J Med. 2017 May 18;376(20):1983-1984.
- Lee EY, Lin J, Noth EM, Hammond SK, Nadeau KC, Eisen EA, Balmes JR. Traffic-Related Air Pollution and Telomere Length in Children and Adolescents Living in Fresno, CA: A Pilot Study. J Occup Environ Med. 2017 May;59(5):446-452.
- Otani IM, Nadeau KC. Biologic Therapies for Immunoglobulin E-mediated Food allergy and Eosinophilic Esophagitis. Immunol Allergy Clin North Am. 2017 May;37(2):369-396.
- Mukai K, Karasuyama H, Kabashima K, Kubo M, Galli SJ. Differences in the Importance of Mast Cells, Basophils, IgE, and IgG versus That of CD4(+) T Cells and ILC2 Cells in Primary and Secondary Immunity to Strongyloides venezuelensis. Infect Immun. 2017 Apr 21;85(5).
- Breton CV, Marsit CJ, Faustman E, Nadeau K, Goodrich JM, Dolinoy DC, Herbstman J, Holland N, LaSalle JM, Schmidt R, Yousefi P, Perera F, Joubert BR, Wiemels J, Taylor M, Yang IV, Chen R, Hew KM, Freeland DM, Miller R, Murphy SK. Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group. Environ Health Perspect. 2017 Apr;125(4):511-526.
- Freeland DMH, Manohar M, Andorf S, Hobson BD, Zhang W, Nadeau KC. Oral immunotherapy for food allergy. Semin Immunol. 2017 Apr;30:36-44.
- MacGinnitie AJ, Rachid R, Gragg H, Little SV, Lakin P, Cianferoni A, Heimall J, Makhija M, Robison R, Chinthrajah RS, Lee J, Lebovidge J, Dominguez T, Rooney C, Lewis MO, Koss J, Burke-Roberts E, Chin K, Logvinenko T, Pongracic JA, Umetsu DT, Spergel J, Nadeau KC, Schneider LC. Omalizumab facilitates rapid oral desensitization for peanut allergy. J Allergy Clin Immunol. 2017 Mar;139(3):873-881.e8.
- Ahuja SK, Manoharan MS, Harper NL, Jimenez F, Hobson BD, Martinez H, Ingale P, Liu YG, Carrillo A, Lou Z, Kellog DL, Ahuja SS, Rather CG, Esch RE, Ramirez DA, Clark RA, Nadeau K, Andrews CP, Jacobs RL, He W. Preservation of epithelial cell barrier function and muted inflammation in resistance to allergic rhinoconjunctivitis from house dust mite challenge. J Allergy Clin Immunol. 2017 Mar;139(3):844-854.
- Mukai K, Gaudenzio N, Gupta S, Vivanco N, Bendall SC, Maecker HT, Chinthrajah RS, Tsai M, Nadeau KC, Galli SJ. Assessing basophil activation by using flow cytometry and mass cytometry in blood stored 24 hours before analysis. J Allergy Clin Immunol. 2017 Mar;139(3):889-899.e11.
- Mukai K, Chinthrajah RS, Nadeau KC, Tsai M, Gaudenzio N, Galli SJ. A new fluorescent-avidin-based method for quantifying basophil activation in whole blood. J Allergy Clin Immunol. 2017 Mar;139(3):889-899.e11.
- Balbino B, Sibilano R, Starkl P, Marichal T, Gaudenzio N, Karasuyama H, Bruhns P, Tsai M, Reber LL, Galli SJ. Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis. J Allergy Clin Immunol. 2017 Feb;139(2):584-596.e10.
- Zhang YZ, Du WX, Fan Y, Yi J, Lyu SC, Nadeau KC, Thomas AL, McHugh T. Purification and Characterization of a Black Walnut (Juglans nigra) Allergen, Jug n 4. J Agric Food Chem. 2017 Jan 18;65(2):454-462.
- Beutier H, Gillis CM, Iannascoli B, Godon O, England P, Sibilano R, Reber LL, Galli SJ, Cragg MS, Van Rooijen N, Mancardi DA, Bruhns P, Jönsson F. IgG subclasses determine pathways of anaphylaxis in mice. J Allergy Clin Immunol. 2017 Jan;139(1):269-280.e7.
- Gebe JA, Yadava K, Ruppert SM, Marshall P, Hill P, Falk BA, Sweere JM, Han H, Kaber G, Medina C, Mikecz K, Ziegler SF, Balaji S, Keswani SG, de Jesus Perez VA, Butte MJ, Nadeau K, Altemeier WA, Fanger N, Bollyky PL. Modified High Molecular Weight Hyaluronan Promotes Allergen-Specific Immune Tolerance. Am J Respir Cell Mol Biol. 2017 Jan;56(1):109-120.
- Sampath V, Tupa D, Graham MT, Chatila TA, Spergel JM, Nadeau KC. Deciphering the black box of food allergy mechanisms. Ann Allergy Asthma Immunol. 2017 Jan;118(1):21-27.
- Sibilano R, Gaudenzio N, DeGorter MK, Reber LL, Hernandez JD, Starkl PM, Zurek OW, Tsai M, Zahner S, Montgomery SB, Roers A, Kronenberg M, Yu M, Galli SJ. A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice. Nat Commun. 2016 Dec 16;7:13696.
- Yu W, Freeland DM, Nadeau KC. Food allergy: immune mechanisms, diagnosis and immunotherapy. Nat Rev Immunol. 2016 Dec;16(12):751-765.
- Zhang Y, Du WX, Fan Y, Yi J, Lyu SC, Nadeau KC, McHugh TH. Identification, characterization, and initial epitope mapping of pine nut allergen Pin k 2. Food Research International. 2016 Dec;90:268-274.
- Walter JE, Rosen LB, Csomos K, Rosenberg JM, Mathew D, Keszei M, Ujhazi B, Chen K, Lee YN, Tirosh I, Dobbs K, Al-Herz W, Cowan MJ, Puck J, Bleesing JJ, Grimley MS, Malech H, De Ravin SS, Gennery AR, Abraham RS, Joshi AY, Boyce TG, Butte MJ, Nadeau KC, Balboni I, Sullivan KE, Akhter J, Adeli M, El-Feky RA, El-Ghoneimy DH, Dbaibo G, Wakim R, Azzari C, Palma P, Cancrini C, Capuder K, Condino-Neto A, Costa-Carvalho BT, Oliveira JB, Roifman C, Buchbinder D, Kumanovics A, Franco JL, Niehues T, Schuetz C, Kuijpers T, Yee C, Chou J, Masaad MJ, Geha R, Uzel G, Gelman R, Holland SM, Recher M, Utz PJ, Browne SK, Notarangelo LD. Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency. J Clin Invest. 2016 Nov 1;126(11).
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- Yip KH, Kolesnikoff N, Hauschild N, Biggs L, Lopez AF, Galli SJ, Kumar S, Grimbaldeston MA. The Nedd4-2/Ndfip1 axis is a negative regulator of IgE-mediated mast cell activation. Nat Commun. 2016 Oct 27;7:13198
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- Mukai K, Tsai M, Starkl P, Marichal T, Galli SJ. IgE and mast cells in host defense against parasites and venoms. Semin Immunopathol. 2016 Sep;38(5):581-603.
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- Farzan SF, Li Z, Korrick SA, Spiegelman D, Enelow R, Nadeau K, Baker E, Karagas MR. Infant Infections and Respiratory Symptoms in Relation to in Utero Arsenic Exposure in a U.S. Cohort. Environ Health Perspect. 2016 Jun;124(6):840-7.
- Zhang Y, Lee B, Du WX, Lyu SC, Nadeau KC, Grauke LJ, Zhang Y, Wang S, Fan Y, Yi J, McHugh TH. Identification and Characterization of a New Pecan [Carya illinoinensis (Wangenh.) K. Koch] Allergen, Car i 2. J Agric Food Chem. 2016 May 25;64(20):4146-51
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- Galli SJ. Toward precision medicine and health: Opportunities and challenges in allergic diseases. J Allergy Clin Immunol. 2016 May;137(5):1289-300.
- Wood RA, Kim JS, Lindblad R, Nadeau K, Henning AK, Dawson P, Plaut M, Sampson HA. A randomized, double-blind, placebo-controlled study of omalizumab combined with oral immunotherapy for the treatment of cow's milk allergy. J Allergy Clin Immunol. 2016 Apr;137(4):1103-10.e1-11.
- Chinthrajah RS, Hernandez JD, Boyd SD, Galli SJ, Nadeau KC. Molecular and cellular mechanisms of food allergy and food tolerance. J Allergy Clin Immunol. 2016 Apr;137(4):984-97.
- Ryan JF, Hovde R, Glanville J, Lyu S-C, Ji X, Gupta S, Tibshirani RJ, Jay DC, Boyd SD, Chinthrajah RS, Davis MM, Galli SJ, Maecker HT, Nadeau KC. Successful immunotherapy induces previously unidentified allergen-specific CD4+ T-cell subsets. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1286-95.
- Bauer RN, Chinthrajah RS, Andorf S, Hobson B, Miller RL, Nadeau KC. T-Cell Immunophenotyping of Second-Hand Smoke-related Asthma. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S95.
- Chang, A, Block W, Bollyky JB, Chinthrajah RS, Nadeau KC, Elizur A. Exploring Correlations Between Cross-Reactive Tree Nuts in Multiple Food Allergic Patients. J Allergy Clin Immunol. 2016 Feb;137(2):AB200.
- Singh S, Kshirsagar RA , Dominguez TLR, Tupa D, Block W, Chinthrajah RS, Nadeau KC. Long-Term Follow-up of Oral Immunotherapy for Multiple Food Allergies. J Allergy Clin Immunol, 2016 Feb;137(2):AB132.
- Elizur A, Bollyky JB, Block W, Nadeau KC. Different Triggers for the Diagnosis of Individual Food Allergies in Multiple Food Allergic Patients. J Allergy Clin Immunol, 2016 Feb;137(2):AB156.
- Prunicki M, Zhou X, de Planell-Saguer M, Miller R, Nadeau KC. Identification of Tr1 Cells and Other CD4+ T Cell Subsets in Humans Using Mass Cytometry: A Tool for Understanding Asthma. J Allergy Clin Immuol, 2016 Feb;137(2):AB410.
- Slatkin SC, Tupa D, Nadeau KC, Chinthrajah RS. Fraction of Exhaled Nitric Oxide (FeNO) and Abdominal Pain and/or Vomiting in Reaction to Oral Food Challenge. J Allergy Clin Immunol, 2016 Feb;137(2):AB135.
- De Schryver S, Dery A, Clarke AE, Nadeau KC, Harada L, Greenwood C, Weatherall K, Daley D, Asai Y, Bamforth F, Ben-Shoshan M. START: Susceptibility to Food Allergies in a Registry of Twins. J Allergy Clin Immunol, 2016 Feb;137(2):AB152
- Zhang Y, Du WX, Fan Y, Nadeau KC, McHugh TH. Prediction and Identification of Korean Pine (Pinus koraiensis) Vicilin As a Food. J Allergy Clin Immunol, 2016 Feb;137(2):AB267.
- Noshirvan A, Petroni DH, Tsai M, Galli SJ, Chintrajah RS, Nadeau KC. Trends in Adverse Reactions Requiring Epinephrine in the Build-up Phase of Oral Immunotherapy. J Allergy Clin Immunol, 2016 Feb;137(2):AB131.
- Galli SJ. The Mast Cell-IgE Paradox: From Homeostasis to Anaphylaxis. Am J Pathol. 2016 Feb;186(2):212-24.
- Ma J, Strub P, Lv N, Xiao L, Camargo CA Jr, Buist AS, Lavori PW, Wilson SR, Nadeau KC, Rosas LG. Pilot randomised trial of a healthy eating behavioural intervention in uncontrolled asthma. Eur Respir J. 2016 Jan;47(1):122-32.
- Hoh RA, Joshi SA, Liu Y, Wang C, Roskin KM, Lee JY, Pham T, Looney TJ, Jackson KJ, Dixit VP, King J, Lyu SC, Jenks J, Hamilton RG, Nadeau KC, Boyd SD. Single B-cell deconvolution of peanut-specific antibody responses in allergic patients. J Allergy Clin Immunol. 2016 Jan;137(1):157-67.
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- Cheng K-C, Zheng D, Tetteh AO, Park H-K, Nadeau KC & Hildemann LM. Personal exposure to airborne particulate matter due to residential dryer lint cleaning. Building and Environment. 2016. 98:145-149.
- Cheng K-C, Park H-K, Tetteh AO, Zheng D, Ouellette NT, Nadeau KC & Hildemann LM. Mixing and sink effects of air purifiers on indoor PM2.5 concentrations: A pilot study of eight residential homes in Fresno, California. Aerosol Science and Technology. 2016. 50(8):835-845.
- Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA Jr, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, Fuhlbrigge A, Gaston BM, Hartert TV, Kolls JK, Lynch SV, Moore WC, Morgan WJ, Nadeau KC, Ownby DR, Solway J, Szefler SJ, Wenzel SE, Wright RJ, Smith RA, Erzurum SC. Future Research Directions in Asthma: An NHLBI Working Group Report. Am J Respir Crit Care Med. 2015 Dec 1;192(11):1366-72.
- Chinthrajah RS, Tupa D, Prince BT, Block WM, Rosa JS, Singh AM, Nadeau K. Diagnosis of Food Allergy. Pediatr Clin North Am. 2015 Dec;62(6):1393-408.
- Prince BT, Mandel MJ, Nadeau K, Singh AM. Gut Microbiome and the Development of Food Allergy and Allergic Disease. Pediatr Clin North Am. 2015 Dec;62(6):1479-92.
- Geifman N, Bollyky J, Bhattacharya S, Butte AJ. Opening clinical trial data:are the voluntary data-sharing portals enough? BMC Med. 2015 Nov 11;13:280.
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- Bégin P, Schulze J, Baron U, Olek S, Bauer RN, Passerini L, Baccheta R, Nadeau KC. Human in vitro induced T regulatory cells and memory T cells share common demethylation of specific FOXP3 promoter region. Clin Transl Allergy. 2015 Oct 20;5:35.
- Vercelli D, Galli SJ. Editorial overview: Allergy and hypersensitivity: New developments in allergy and type 2 immunity: never a dull moment. Curr Opin Immunol. 2015 Oct;36:ix-xi.
- Roskin KM, Simchoni N, Liu Y, Lee JY, Seo K, Hoh RA, Pham T, Park JH, Furman D, Dekker CL, Davis MM, James JA, Nadeau KC, Cunningham-Rundles C, Boyd SD. IgH sequences in common variable immune deficiency reveal altered B cell development and selection. Sci Transl Med. 2015 Aug 26;7(302):302ra135
- Lambrecht BN, Galli SJ. SnapShot: Integrated Type 2 Immune Responses. Immunity. 2015 Aug 18; 43(2):408-408.
- Quake C, Nadeau KC. The role of epigenetic mediation and the future of food allergy research. Semin Cell Dev Biol. 2015 Jul;43:125-30.
- Sabounchi S, Bollyky J, Nadeau K. Review of Environmental Impact on the Epigenetic Regulation of Atopic Diseases. Curr Allergy Asthma Rep. 2015 Jun;15(6):533.
- Bégin P, Nadeau KC. Changes in peanut-specific T-cell clonotype with oral immunotherapy. J Allergy Clin Immunol. 2015 Jun;135(6):1636-8.
- Reber LL, Sibilano R, Mukai K, Galli SJ. Potential effector and immunoregulatory functions of mast cells in mucosal immunity. Mucosal Immunol. 2015 May; 8(3):444-63.
- Mathieu AL, Verronese E, Rice GI, Fouyssac F, Bertrand Y, Picard C, Chansel M, Walter JE, Notarangelo LD, Butte MJ, Nadeau KC, Csomos K, Chen DJ, Chen K, Delgado A, Rigal C, Bardin C, Schuetz C, Moshous D, Reumaux H, Plenat F, Phan A, Zabot MT, Balme B, Viel S, Bienvenu J, Cochat P, van der Burg M, Caux C, Kemp EH, Rouvet I, Malcus C, Méritet JF, Lim A, Crow YJ, Fabien N, Ménétrier-Caux C, De Villartay JP, Walzer T, Belot A. PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator-dependent autoimmunity. J Allergy Clin Immunol. 2015 Apr 1; S0091-6749(15)00185-2.
- Hong X, Hao K, Ladd-Acosta C, Hansen KD, Tsai HJ, Liu X, Xu X, Thornton TA, Caruso D, Keet CA, Sun Y, Wang G, Luo W, Kumar R, Fuleihan R, Singh AM, Kim JS, Story RE, Gupta RS, Gao P, Chen Z, Walker SO, Bartell TR, Beaty TH, Fallin MD, Schleimer R, Holt PG, Nadeau KC, Wood RA, Pongracic JA, Weeks DE, Wang X. Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children. Nat Commun. 2015 Feb 24;6:6304.
- Bauer RN, Manohar M, Singh AM, Jay DC, Nadeau KC. The future of biologics: Applications for food allergy. J Allergy Clin Immunol. 2015 Feb;135(2):312-323.
- Pajno GB, Nadeau KC, Passalacqua G, Caminiti L, Hobson B, Jay DC, Arasi S, Chiera F, Salzano G. The evolution of allergen and non-specific immunotherapy: past achievements, current applications and future outlook. Expert Rev Clin Immunol. 2015 Jan;11(1):141-54.
- Hew KM, Walker AI, Kohli A, Garcia M, Syed A, McDonald-Hyman C, Noth B, Mann J, Pratt B, Balmes J, Hammond K, Eisen E, Nadeau KC. Childhood exposure to ambient polycyclic aromatic hydrocarbons is linked to epigenetic modifications and impaired systemic immunity in T cells. Clin Exp Allergy. 2015 Jan;45(1):238-48.
- Graham MT, Nadeau KC. Lessons learned from mice and man: mimicking human allergy through mouse models. Clin Immunol. 2014 Nov;155(1):1-16.
- Sleiman P, Wang ML, Cianferoni A, Aceves S, Gonsalves N, Nadeau KC, Bredenoord A, Furuta G, Spergel J, and Hakonarson H. GWAS identifies four novel eosinophilic esophagitis loci. Nature Communications. 2014 Nov 19;5:5593. *Participated in enrolling patients, provided technical support and material support.
- Arasi S, Klingbeil E, Dominguez T, and Nadeau KC. Two year long term data on Quality of Life in Multiple Food Allergy Oral Immunotherapy. Allergy, Asthma, and Clinical Immunology. 2014 Nov; 10:57
- Jay D, Manohar M, and Nadeau KC. Immune Mechanisms of Sublingual Immunotherapy. Current Allergy and Asthma Reports. 2014 Nov;14(11):473.
- Lv N, Xiao L, Camargo C, Wilson S, Buist S, Strub P, Nadeau K, and Ma J. Abdominal and General Adiposity and Level of Asthma Control in Adults with Uncontrolled Asthma. Annals of the American Thoracic Society. 2014 Oct;11(8):1218-24. *Participated in acquisition of data, technical support, material support, and analysis and interpretation of data.
- Luskin AT, Chipps BE, Rasouliyan L, Miller DP, Haselkorn T, Dorenbaum A. Impact of asthma exacerbations and asthma triggers on asthma-related quality of life in patients with severe or difficult-to-treat asthma. J Allergy Clin Immunol Pract. 2014 Sep-Oct; 2(5):544-52. [Epub 2014 Jul 3]
- Rothenberg ME, Wen T, Greenberg A, Alpan O, Enav B, Hirano I, Nadeau KC, Kaiser S, Peters T, Perez A, Jones I, Arm JP, Strieter RM, Sabo R, Gunawardena KA. Intravenous anti-IL-13 mAb QAX576 for the treatment of eosinophilic esophagitis. J Allergy Clin Immunol. 2014 Sep 13. *Participated in enrolling patients in the study, acquisition of data, and analysis and interpretation of data.
- Alexander ES, Martin LJ, Collins MH, Kottyan LC, Sucharew H, He H, Mukkada VA, Succop PA, Abonia JP, Foote H, Eby MD, Grotjan TM, Greenler AJ, Dellon ES, Demain JG, Furuta GT, Gurian LE, Harley JB, Hopp RJ, Kagalwalla A, Kaul A, Nadeau KC, Noel RJ, Putnam PE, von Tiehl KF, Rothenberg ME. Twin and family studies reveal strong environmental and weaker genetic cues explaining heritability of eosinophilic esophagitis. J Allergy Clin Immunol. 2014 Sep 1. *Participated in enrolling patients in the study and acquisition of data.
- Sampson H, Aceves S, Bock A, James J, Jones S, Lang D, Nadeau KC, Nowak-Wegrzyn A, Oppenheimer J, Perry T, Randolph C, Sicherer S, Simon R, Vickery B, and Wood R. Food Allergy: A practice parameter update-2014. J. of Allergy and Clinical Immunology. 2014 Aug. E publication. *Participated in design of parameters, material support, and review of data.
- Manohar M and Nadeau KC. The Potential of anti-IgE in Food Allergy Therapy. Current Treatment Options in Allergy. 2014 Jun 1;1(2):145-156
- Padula AM, Balmes JR, Eisen EA, Mann J, Noth EM, Lurmann FW, Pratt B, Tager IB, Nadeau K, Hammond SK. Ambient polycyclic aromatic hydrocarbons and pulmonary function in children. J Expo Sci Environ Epidemiol. 2014 Jun 18. *Participated in conception and design, enrolling patients in the study, acquisition of data, and analysis and interpretation of data.
- McKenzie RB, Berquist WE, Nadeau KC, Louie CY, Chen SF, Sibley RK, Glader BE, Wong WB, Hofmann LV, Esquivel CO, Cox KL. Novel protocol including liver biopsy to identify and treat CD8+ T-cell predominant acute hepatitis and liver failure. Pediatr Transplant. 2014 Jun 14. *Participated in conception and design, enrolling patients in the study, acquisition of data, and analysis and interpretation of data.
- Begin P, Chinthrajah RS, Nadeau KC. Oral immunotherapy for the treatment of food allergy. Hum Vaccin Immunother. 2014 Jun 5;10(8).
- Begin P and Nadeau KC. Epigenetic regulation of asthma and allergic disease. Allergy, Asthma, and Clinical Immunology. 2014 May 28;10 (1):27.
- Otani IM, Bégin P, Kearney C, Dominguez TL, Mehrotra A, Bacal LR, Wilson S, Nadeau KC. Multiple-allergen oral immunotherapy improves quality of life in caregivers of food-allergic pediatric subjects. Allergy Asthma Clin Immunol. 2014 May 12;10(1):25.
- Jones PP, Nadeau KC. Introduction to the special issue on Stanford Immunology. Immunol Res. 2014 May;58(2-3):161-3.
- Pellerin L, Jenks JA, Bégin P, Bacchetta R, Nadeau KC. Regulatory T cells and their roles in immune dysregulation and allergy. Immunol Res. 2014 May;58(2-3):358-68.
- Klingbeil EC, Hew KM, Nygaard UC, Nadeau KC. Polycyclic aromatic hydrocarbons, tobacco smoke, and epigenetic remodeling in asthma. Immunol Res. 2014 May;58(2-3):369-73.
- Bégin P, Dominguez T, Wilson SP, Bacal L, Mehrotra A, Kausch B, Trela A, Tavassoli M, Hoyte E, O'Riordan G, Blakemore A, Seki S, Hamilton RG, Nadeau KC. Phase 1 results of safety and tolerability in a rush oral immunotherapy protocol to multiple foods using Omalizumab. Allergy, Asthma, and Clinical Immunology. 2014 Feb 20;10(1):7.
- Syed A, Garcia M, Kohli A, Maecker H, Tsai M, Galli S, and Nadeau KC. Peanut oral immunotherapy results in increased antigen-induced Treg function and hypomethylation of FOXP3. The Journal of Allergy and Clinical Immunology. 2014 Feb;133(2):500-10.
- Kanai T, Jenks J, Seki S, Bacchetta R, and Nadeau KC. Identification of STAT5A and STAT5B Target Genes in Human T cells. PLoS One. 2014 Jan 30;9(1):e86790.
- Bégin P, Winterroth LC, Dominguez T, Wilson SP, Bacal L, Mehrotra A, Kausch B, Trela A, Hoyte E, O'Riordan G, Seki S, Blakemore A, Woch M, Hamilton RG, Nadeau KC. Safety and feasibility of oral immunotherapy to multiple allergens for food allergy. Allergy, Asthma, and Clinical Immunology. 2014 Jan 15;10(1):1.
- Liu, J, Zhang, L, Winterroth, L, Garcia, M, Weiman, S, Wong, J, Sunwoo, J, and Nadeau, KC. Epigenetically-mediated pathogenic effects of phenanthrene on regulatory T cells. J Toxicol. 2013; 967-981.
- Reber LL, Marichal T, Mukai K, Kita Y, Tokuoka SM, Roers A, Hartmann K, Karasuyama H, Nadeau KC, Tsai M, Galli SJ. Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice. J Allergy Clin Immunol. 2013 Oct;132(4):881-8. *Participated in obtaining funding, analysis and interpretation of data.
- Syed A, Kohli A, and Nadeau KC. Food allergy diagnosis and therapy: where are we now? Immunotherapy. 2013 Sep; 5(9):931-44.
- Chen R, Giliani S, Lanzi G, Mias GI, Lonardi S, Dobbs K, Manis J, Im H, Gallagher JE, Phanstiel DH, Euskirchen G, Lacroute P, Bettinger K, Moratto D, Weinacht K, Montin D, Gallo E, Mangili G, Porta F, Notarangelo LD, Pedretti S, Al-Herz W, Alfahdli W, Comeau AM, Traister RS, Pai SY, Carella G, Facchetti F, Nadeau KC, Snyder M, Notarangelo LD. Whole-exome sequencing identifies tetratricopeptide repeat domain 7A (TTC7A) mutations for combined immunodeficiency with intestinal atresias. J Allergy Clin Immunol. 2013 Sep;132(3):656-664. *Participated in acquisition of data, and analysis and interpretation of data.
- Syed, A, Hew K, Kohli A, Knowlton G, Nadeau KC. Air Pollution and Epigenetics. Journal of Environmental Protection. 2013 Aug; 4:8A, 114-122.
- Jenks JA, Seki S, Kanai T, Huang J, Morgan AA, Scalco RC, Nath R, Bucayu R, Wit JM, Al-Herz W, Ramadan D, Jorge AA, Bacchetta R, Hwa V, Rosenfeld R, Nadeau KC. Differentiating the roles of STAT5B and STAT5A in human CD4+ T cells. Clin Immunol. 2013 Aug;148(2):227-36.
- Dominguez TL, Bégin P, Nadeau KC. The use of epinephrine in acute allergic reaction to food. Pediatric Annals. 2013 Jul;42(7):293-5.
- Bégin P, Nadeau KC. Diagnosis of food allergy. Pediatr Ann. 2013 Jun 1;42(6):102-9.
- Iyengar SR, Hoyte EG, Loza A, Bonaccorso S, Chiang D, Umetsu DT, Nadeau KC. Immunologic effects of omalizumab in children with severe refractory atopic dermatitis: a randomized, placebo-controlled clinical trial. Int Arch Allergy Immunol. Jun 2013;162(1):89-93
- Ma J, Strub P, Lavori PW, Buist AS, Camargo CA Jr, Nadeau KC, Wilson SR, Xiao L. DASH for asthma: A pilot study of the DASH diet in not-well-controlled adult asthma. Contemporary Clinical Trials. 2013 May 3. *Participated in acquisition of data, analysis and interpretation of data, technical, and material support.
- Le-Carlson M, Seki S, Abarbanel D, Quiros A, Cox K, and Nadeau KC. Markers of antigen presentation and activation on eosinophils and T-cells in the esophageal tissue of patients with eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2013 Mar;56(3):257-62.
- Abarbanel DN, Seki SM, Davies Y, Marlen N, Benavides JA, Cox K, Nadeau KC, Cox KL. Immunomodulatory Effect of Vancomycin on Treg in Pediatric Inflammatory Bowel Disease and Primary Sclerosing Cholangitis. J Clin Immunol. 2013 Feb;33(2):397-406. *Participated in acquisition of data, analysis and interpretation of data, drafting of manuscript, critical revision of the manuscript for important intellectual content, technical support, material support, and statistical analysis.
- Runyon RS, Cachola LM, Rajeshuni N, Hunter T, Garcia M, Ahn R, Lurmann F, Krasnow R, Jack LM, Miller RL, Swan GE, Kohli A, Jacobson AC, and Nadeau KC. Asthma discordance in twins is linked to epigenetic modifications of T cells. PLoS One. 2012;7(11): p. 487-496.
- Kanai T, Jenks J, Nadeau KC. The STAT5b pathway defect and Autoimmunity. Frontiers in Immunology. 2012; 3:234.
- Kohli, A, Garcia, M, Miller, R, Maher, C, Humblet, O, Hammond, K, and Nadeau, KC. Secondhand smoke in combination with ambient air pollution exposure is associated with increased CpG methylation and decreased expression of IFN-γ in T effector cells and Foxp3 in T regulatory cells in children. J. of Clinical Epigenetics. 2012 Sep 25;4(1):17. 2012.
- Swamy RS, Reshamwala N, Hunter T, Vissamsetti S, Santos CB, Baroody FM, Hwang PH, Hoyte EG, Garcia MA, Nadeau KC. Epigenetic modifications and improved regulatory T-cell function in subjects undergoing dual sublingual immunotherapy. J Allergy Clin Immunol. 2012 Jul;130(1):215-224. (Recommended by Faculty 1000)
- Yu GP, Weldon B, Neale-May S, Nadeau KC. The Safety of Peanut Oral Immunotherapy in Peanut-Allergic Subjects in a Single-Center Trial. Int Arch Allergy Immunol. 2012 Jun 1;159(2):179-182.
- Gernez Y, Tirouvanziam R, Reshamwala N, Yu G, Weldon BC, Galli SJ, Herzenberg LA, Nadeau KC. Modulation of mTOR effector phosphoproteins in blood basophils from allergic patients. J Clin Immunol. 2012 Jun;32(3):565-73.
- Bedoret D, Singh AK, Shaw V, Hoyte EG, Hamilton R, DeKruyff RH, Schneider LC, Nadeau KC (co-senior author), Umetsu DT. Changes in antigen-specific T-cell number and function during oral desensitization in cow's milk allergy enabled with omalizumab. Mucosal Immunol. 2012 May;5(3):267-76.
- Morgan AA, Pyrgos VJ, Nadeau KC, Williamson PR, Butte AJ. Multiplex meta-analysis of RNA expression to identify genes with variants associated with immune dysfunction. J Am Med Inform Assoc. 2012 Mar-Apr;19(2):284-8. *Participated in enrolling patients in the study, acquisition of data, and analysis and interpretation of data.
- Chen R, Mias GI, Li-Pook-Than J, Jiang L, Lam HY, Chen R, Miriami E, Karczewski KJ, Hariharan M, Dewey FE, Cheng Y, Clark MJ, Im H, Habegger L, Balasubramanian S, O'Huallachain M, Dudley JT, Hillenmeyer S, Haraksingh R, Sharon D, Euskirchen G, Lacroute P, Bettinger K, Boyle AP, Kasowski M, Grubert F, Seki S, Garcia M, Whirl-Carrillo M, Gallardo M, Blasco MA, Greenberg PL, Snyder P, Klein TE, Altman RB, Butte AJ, Ashley EA, Gerstein M, Nadeau KC, Tang H, Snyder M. Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell. 2012 Mar 16;148(6):1293-307. *Participated in enrolling patients in the study, acquisition of data, and analysis and interpretation of data.
- Recher M, Burns S, de la Fuente MA, Volpi S, Dahlberg C, Walter J, Moffitt K, Matthew D, Honke N, Lang, P, Patrizi L, Falet H, Keszei M, Mizui M, Csizmadia E, Candotti F, Nadeau KC, Bouma G, Delmonte O, Frugoni F, Fomin A, Buchbinder D, Lundequist E-M, Massaad MJ, Tsokos G, Hartwig J, Manis J, Terhorst C, Geha R, Snapper S, Lang K, Malley R, Westerberg L, Thrasher A, Notarangelo L. B-cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein causes severe abnormalities of the peripheral B-cell compartment in mice. Blood. 2012 Mar 22;119(12):2819-28. *Participated in enrolling patients in the study, and analysis and interpretation of data.
- Pedroza L, Kumar V, Mace E, Nadeau KC, Perez E, Ruuskanen O, Orange J. AIRE contributes to Dectin-1-induced TNF-a production 1 and complexes with CARD9, Syk, and Dectin-1. J Allergy Clin Immunol. 2012 Feb;129(2):464-72. *Participated in enrolling patients in the study and analysis and interpretation of data.
- Nadeau KC, Kohli A, Iyengar S, DeKruyff RH, Umetsu DT. Oral immunotherapy and anti-IgE antibody-adjunctive treatment for food allergy. Immunol Allergy Clin North Am. 2012 Feb;32(1):111-33.