Eligibility criteria for subjects without a history of clinical coronary disease in the ADVANCE study
Cohort 4 (n = 264): “Young Controls from Kaiser”
Inclusion
- Membership in KPNC continuously since 1/1/1998
- Age on 6/30/2003 between 30 and 45 years for males and 30 and 55 years for females
- Living in Oakland, San Francisco, Berkeley, Emeryville, Piedmont, Richmond or Albany, California
Exclusion
- Evidence in the electronic databases (going back to 01/01/1996) of any of the following: atherosclerotic vascular disease (including CAD, CHF, stroke, PVD, cerebrovascular disease, and vascular disease not otherwise specified), HIV, dementia, cancer, cirrhosis, renal failure, entry in “no contact list”, no assigned PCP, and remote distance from the study clinics.
- A report during a screening interview an inability to speak and write English, or of any of the above exclusion criteria at any time.
Cohort 5 (n = 479): “Young Controls from CARDIA”
Inclusion
- Participants in the CARDIA study with white/European and African American ancestry originally recruited in the Oakland KPNC field center in 1985-86 who completed the year 15 examination in 2000-2001 and had adequate samples of DNA.
Exclusion
- A personal history of clinically significant CAD or documented CAD by CARDIA investigators
Cohort 6 (n = 1023): “Older Controls”
Inclusion
- Membership in KPNC continuously since 1/1/1996
- Age on 6/30/2001 between 60 and 69 years
Exclusion
- Evidence in the electronic databases (going back to 01/01/1996) of any of the following: atherosclerotic vascular disease (including CAD, CHF, stroke, PVD, cerebrovascular disease, and vascular disease not otherwise specified), HIV, dementia, cancer, cirrhosis, renal failure, entry in “no contact list”, no assigned PCP, and remote distance from the study clinics.
- A report during a screening interview an inability to speak and write English, or of any of the above exclusion criteria at any time.
