Stanford ADRC Publications

2020

Gate D, Saligrama N, Leventhal O, Yang AC, Unger MS, Middeldorp J, Chen K, Lehallier B, Channappa D, De Los Santos MB, McBride A, Pluvinage J, Elahi F, Tam GK, Kim Y, Greicius M, Wagner AD, Aigner L, Galasko DR, Davis MM, Wyss-Coray T. Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease. Nature. 2020;577(7790):399-404. PubMed PMID: 31915375; PubMed Central PMCID PMC7445078.

Belloy ME, Napolioni V, Han SS, Le Guen Y, Greicius MD. Association of Klotho-VS heterozygosity with risk of Alzheimer disease in individuals who carry ApoE4. JAMA neurology. 2020; 77(7):849-862. PubMed PMID: 32282020; PubMed Central PMCID: PMC7154955.

Boggess MB, Barber JM, Jicha GA, Caban-Holt A. Subjective memory complaints are an important surrogate for objective cognitive performance in African Americans. Alzheimer disease and associated disorders. 2020;34(1):79-84. PubMed PMID: 31633556; PubMed Central PMCID: PMC7170708.

Cholerton B, Poston KL, Tian L, Quinn JF, Chung KA, Hiller AL, Hu SC, Specketer K, Montine TJ, Edwards KL, Zabetian CP. Participant and study partner reported impact of cognition on functional activities in Parkinson's disease. Movement disorders clinical practice. 2020;7(1):61-69. PubMed PMID: 31970213; PubMed Central PMCID: PMC6962683.

Culhane JE, Chan KCG, Teylan MA, Chen YC, Mock C, Gauthreaux K, Kukull WA. Factor consistency of neuropsychological test battery versions in the NACC uniform data set. Alzheimer disease and associated disorders. 2020;34(2):175-177. PubMed PMID: 32218065; PubMed Central PMCID: PMC7242135.

Fremin BJ, Sberro H, Bhatt AS. MetaRibo-Seq measures translation in microbiomes. Nature communications. 2020;11(1):3268. PubMed PMID: 32601270; PubMed Central PMCID: PMC7324362.

Gold D, Rosowsky E, Piryatinsky I, Sinclair SJ. Comparing patient and informant ratings of depressive symptoms in various stages of Alzheimer's disease. Neuropsychology. 2020;34(5):535-550. PubMed PMID: 32191055; PubMed Central PMCID: PMC7319875.

Hackett K, Mis R, Drabick DAG, Giovannetti T. Informant reporting in mild cognitive impairment: sources of discrepancy on the functional activities questionnaire. Journal of the International Neuropsychological Society: JINS. 2020;26(5):503-514. PubMed PMID: 31964443; PubMed Central PMCID: PMC7205566.

John SE, Evans SA, Hanfelt J, Loring DW, Goldstein FC. Subjective memory complaints in White and African American participants. Journal of geriatric psychiatry and neurology. 2020;33(3):135-143. PubMed PMID: 31409180; PubMed Central PMCID: PMC7015770.

Ledger C, Karameh WK, Munoz DG, Fischer CE, Schweizer TA. Gender role in sleep disturbances among older adults with traumatic brain injury. International review of psychiatry (Abingdon, England). 2020;32(1):39-45. PubMed PMID: 31544552; PubMed Central PMCID: PMC7255060.

Liew TM. Neuropsychiatric symptoms in cognitively normal older persons, and the association with Alzheimer's and non-Alzheimer's dementia. Alzheimer's research & therapy. 2020;12(1):35. PubMed PMID: 32234066; PubMed Central PMCID: PMC7110750.

Mock C, Teylan M, Beecham G, Besser L, Cairns NJ, Crary JF, Katsumata Y, Nelson PT, Kukull W. The utility of the National Alzheimer's Coordinating Center's database for the rapid assessment of evolving neuropathologic conditions. Alzheimer disease and associated disorders. 2020;34(2):105-111. PubMed PMID: 32304374; PubMed Central PMCID: PMC7242145.

Moss EL, Maghini DG, Bhatt AS. Complete, closed bacterial genomes from microbiomes using nanopore sequencing. Nature biotechnology. 2020;38(6):701-707. PubMed PMID: 32042169; PubMed Central PMCID: PMC7283042.

Nelson MJ, Moeller S, Basu A, Christopher L, Rogalski EJ, Greicius M, Weintraub S, Bonakdarpour B, Hurley RS, Mesulam MM. Taxonomic interference associated with phonemic paraphasias in agrammatic primary progressive aphasia. Cerebral cortex (New York, N.Y.: 1991). 2020;30(4):2529-2541. PubMed PMID: 31800048; PubMed Central PMCID: PMC7174997.

Ording AG, Horváth-Puhó E, Veres K, Glymour MM, Rørth M, Sørensen HT, Henderson VW. Cancer and risk of Alzheimer's disease: small association in a nationwide cohort study. Alzheimer's & dementia: the journal of the Alzheimer's Association. 2020;16(7):953-964. PubMed PMID: 32432415; PubMed Central PMCID: PMC7351601.

Periyakoil VJ. The need of the hour: culturally competent care for seriously ill patients. Journal of palliative medicine. 2020;23(4):440-441. PubMed PMID: 32216689; PubMed Central PMCID: PMC7364299.

Poston KL, Ua Cruadhlaoich MAI, Santoso LF, Bernstein JD, Liu T, Wang Y, Rutt B, Kerchner GA, Zeineh MM. Substantia nigra volume dissociates bradykinesia and rigidity from tremor in Parkinson's disease: a 7 Tesla imaging study. Journal of Parkinson's disease. 2020;10(2):591-604. PubMed PMID: 32250317; PubMed Central PMCID: PMC7242837.

Ryman SG, Poston KL. MRI biomarkers of motor and non-motor symptoms in Parkinson's disease. Parkinsonism & related disorders. 2020;73:85-93. PubMed PMID: 31629653; PubMed Central PMCID: PMC7145760.

Schaffert J, LoBue C, White CL 3rd, Wilmoth K, Didehbani N, Lacritz L, Nguyen T, Peters ME, Fields L, Li C, Cullum CM. Risk factors for earlier dementia onset in autopsy-confirmed Alzheimer's disease, mixed Alzheimer's with Lewy bodies, and pure Lewy body disease. Alzheimer's & dementia: the journal of the Alzheimer's Association. 2020;16(3):524-530. PubMed PMID: 32043803; PubMed Central PMCID: PMC7067630.

Shinohara M, Tashiro Y, Suzuki K, Fukumori A, Bu G, Sato N. Interaction between APOE genotype and diabetes in cognitive decline. Alzheimer's & dementia (Amsterdam, Netherlands). 2020;12(1):e12006. PubMed PMID: 32211501; PubMed Central PMCID: PMC7085280.

Xiong C, Luo J, Coble D, Agboola F, Kukull W, Morris JC. Complex interactions underlie racial disparity in the risk of developing Alzheimer's disease dementia. Alzheimer's & dementia: the journal of the Alzheimer's Association. 2020;16(4):589-597. PubMed PMID: 32067357; PubMed Central PMCID: PMC7259475.

Younan D, Petkus AJ, Widaman KF, Wang X, Casanova R, Espeland MA, Gatz M, Henderson VW, Manson JE, Rapp SR, Sachs BC, Serre ML, Gaussoin SA, Barnard R, Saldana S, Vizuete W, Beavers DP, Salinas JA, Chui HC, Resnick SM, Shumaker SA, Chen JC. Particulate matter and episodic memory decline mediated by early neuroanatomic biomarkers of Alzheimer's disease. Brain: a journal of neurology. 2020;143(1):289-302. PubMed PMID: 31746986; PubMed Central PMCID: PMC6938036.

Wilson EN, Swarovski MS, Linortner P, Shahid M, Zuckerman AJ, Wang Q, Channappa D, Minhas PS, Mhatre SD, Plowey ED, Quinn JF, Zabetian CP, Tian L, Longo FM, Cholerton B, Montine TJ, Poston KL, Andreasson KI. Soluble TREM2 is elevated in Parkinson's disease subgroups with increased CSF tau. Brain: a journal of neurology. 2020;143(3):932-943. PubMed PMID: 32065223; PubMed Central PMCID: PMC7089668.

2019

Andrews JS, Desai U, Kirson NY, Zichlin ML, Ball DE, Matthews BR. Disease severity and minimal clinically important differences in clinical outcome assessments for Alzheimer's disease clinical trials. Alzheimer's & dementia (New York, N. Y.). 2019;5:354-363. PubMed PMID: 31417957; PubMed Central PMCID: PMC6690415.

Bailey KC, Burmaster SA, Schaffert J, LoBue C, Vela D, Rossetti H, Cullum CM. Associations of race-ethnicity and history of traumatic brain injury with age at onset of Alzheimer's disease. The journal of neuropsychiatry and clinical neurosciences. 2019;32(3):280-285. PubMed PMID: 31619118; PubMed Central PMCID: PMC7162699.

Bardach SH, Jicha GA, Karanth S, Zhang X, Abner EL. Genetic sample provision among National Alzheimer's Coordinating Center participants. Journal of Alzheimer's disease: JAD. 2019;69(1):123-133. PubMed PMID: 30958359; PubMed Central PMCID: PMC6513699.

Bayram E, Shan G, Cummings JL. Associations between comorbid TDP-43, Lewy body pathology, and neuropsychiatric symptoms in Alzheimer's disease. Journal of Alzheimer's disease: JAD. 2019;69(4):953-961. PubMed PMID: 31127776; PubMed Central PMCID: PMC6597983.

Belloy ME, Napolioni V, Greicius MD. A quarter century of ApoE and Alzheimer's disease: progress to date and the path forward. Neuron. 2019;101(5):820-838. PubMed PMID: 30844401; PubMed Central PMCID: PMC6407643.

Besser LM, Mock C, Teylan MA, Hassenstab J, Kukull WA, Crary JF. Differences in cognitive impairment in primary age-related tauopathy versus Alzheimer disease. Journal of neuropathology and experimental neurology. 2019; 78(3):219-228. PubMed PMID: 30715383; PubMed Central PMCID: PMC6380319.

Brunger AT, Choi UB, Lai Y, Leitz J, White KI, Zhou Q. The pre-synaptic fusion machinery. Current opinion in structural biology. 2019;54:179-188. PubMed PMID: 30986753; PubMed Central PMCID: PMC6939388.

Burke SL, Hu T, Naseh M, Fava NM, O'Driscoll J, Alvarez D, Cottler LB, Duara R. Factors influencing attrition in 35 Alzheimer's Disease Centers across the USA: a longitudinal examination of the National Alzheimer's Coordinating Center's Uniform Data Set. Aging clinical and experimental research. 2019;31(9):1283-1297. PubMed PMID: 30535620; PubMed Central PMCID: PMC6557707.

Carpenter J, Miller SC, Kolanowski AM, Karel MJ, Periyakoil VS, Lowery J, Levy C, Sales AE, Ersek M. Partnership to enhance resident outcomes for community living center residents with dementia: description of the protocol and preliminary findings. Journal of gerontological nursing. 2019;45(3):21-30. PubMed PMID: 30789986; PubMed Central PMCID: PMC7310712.

Chen KT, Gong E, de Carvalho Macruz FB, Xu J, Boumis A, Khalighi M, Poston KL, Sha SJ, Greicius MD, Mormino E, Pauly JM, Srinivas S, Zaharchuk G. Ultra-low-dose 18F-Florbetaben amyloid PET imaging using deep learning with multi-contrast MRI inputs. Radiology. 2019;290(3):649-656. PubMed PMID: 30526350; PubMed Central PMCID: PMC6394782.

Chavda R, Cao JS, Benge JF. Neuropsychological impact of white matter hyperintensities in older adults without dementia. Applied neuropsychology. Adult. 2019:1-9. PubMed PMID: 31287337; PubMed Central PMCID: PMC6949427.

Chiou SH, Austin MD, Qian J, Betensky RA. Transformation model estimation of survival under dependent truncation and independent censoring. Statistical methods in medical research. 2019;28(12):3785-3798. PubMed PMID: 30543153; PubMed Central PMCID: PMC6565507.

Cho H, Matthews GJ, Harel O. Confidence intervals for the area under the receiver operating characteristic curve in the presence of ignorable missing data. International statistical review = Revue internationale de statistique. 2019; 87(1):152-177. PubMed PMID: 31007356; PubMed Central PMCID: PMC6472951.

Cholerton B, Weiner MW, Nosheny RL, Poston KL, Mackin RS, Tian L, Ashford JW, Montine TJ. Cognitive performance in Parkinson's disease in the Brain Health Registry. Journal of Alzheimer's disease: JAD. 2019;68(3):1029-1038. PubMed PMID: 30909225; PubMed Central PMCID: PMC6497062.

Cloutier M, Gauthier-Loiselle M, Gagnon-Sanschagrin P, Guerin A, Hartry A, Baker RA, Duffy R, Gwin K, Sanon Aigbogun M. Institutionalization risk and costs associated with agitation in Alzheimer's disease. Alzheimer's & dementia (New York, N. Y.). 2019;5:851-861. PubMed PMID: 31799369; PubMed Central PMCID: PMC6881649.

Cotter K, Siskind CE, Sha SJ, Hanson-Kahn AK. Positive attitudes and therapeutic misconception around hypothetical clinical trial participation in the Huntington's disease community. Journal of Huntington's disease. 2019;8(4):421-430. PubMed PMID: 31594242; PubMed Central PMCID: PMC6839474.

Creese B, Vassos E, Bergh S, Athanasiu L, Johar I, Rongve A, Medbøen IT, Vasconcelos Da Silva M, Aakhus E, Andersen F, Bettella F, Braekhus A, Djurovic S, Paroni G, Proitsi P, Saltvedt I, Seripa D, Stordal E, Fladby T, Aarsland D, Andreassen OA, Ballard C, Selbaek G. Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease. Translational psychiatry. 2019;9(1):273. PubMed PMID: 31641104; PubMed Central PMCID: PMC6805870.

Dallaire-Théroux C, Beheshti I, Potvin O, Dieumegarde L, Saikali S, Duchesne S. Braak neurofibrillary tangle staging prediction from in vivo MRI metrics. Alzheimer's & dementia (Amsterdam, Netherlands). 2019;11:599-609. PubMed PMID: 31517022; PubMed Central PMCID: PMC6731211.

Evans S, McRae-McKee K, Hadjichrysanthou C, Wong MM, Ames D, Lopez O, de Wolf F, Anderson RM. Alzheimer's disease progression and risk factors: A standardized comparison between six large data sets. Alzheimer's & dementia (New York, N. Y.). 2019;5:515-523. PubMed PMID: 31650008; PubMed Central PMCID: PMC6804515.

Grill JD, Kwon J, Teylan MA, Pierce A, Vidoni ED, Burns JM, Lindauer A, Quinn J, Kaye J, Gillen DL, Nan B. Retention of Alzheimer disease research participants. Alzheimer disease and associated disorders. 2019;33(4):299-306. PubMed PMID: 31567302; PubMed Central PMCID: PMC6878201.

Han JY, Besser LM, Xiong C, Kukull WA, Morris JC. Cholinesterase inhibitors may not benefit mild cognitive impairment and mild Alzheimer disease dementia. Alzheimer disease and associated disorders. 2019;33(2):87-94. PubMed PMID: 30633043; PubMed Central PMCID: PMC6542289.

Hendershott TR, Zhu D, Llanes S, Zabetian CP, Quinn J, Edwards KL, Leverenz JB, Montine T, Cholerton B, Poston KL. Comparative sensitivity of the MoCA and Mattis Dementia Rating Scale-2 in Parkinson's disease. Movement disorders: official journal of the Movement Disorder Society. 2019;34(2):285-291. PubMed PMID: 30776152; PubMed Central PMCID: PMC6532623.

Hobel Z, Isenberg AL, Raghupathy D, Mack W, Pa J. APOEɛ4 Gene Dose and Sex Effects on Alzheimer's disease MRI biomarkers in older adults with mild cognitive impairment. Journal of Alzheimer's disease: JAD. 2019;71(2):647-658. PubMed PMID: 31424388; PubMed Central PMCID: PMC6839478.

Hsieh CH, Li L, Vanhauwaert R, Nguyen KT, Davis MD, Bu G, Wszolek ZK, Wang X. Miro1 marks Parkinson's disease subset and Miro1 reducer rescues neuron loss in Parkinson's models. Cell metabolism. 2019;30(6):1131-1140.e7. PubMed PMID: 31564441; PubMed Central PMCID: PMC6893131.

Kiselica AM, Benge JF. Quantitative and qualitative features of executive dysfunction in frontotemporal and Alzheimer's dementia. Applied neuropsychology. Adult. 2019:1-15. PubMed PMID: 31424275; PubMed Central PMCID: PMC7028481.

Kiselica AM, Benge JF. Quantitative and qualitative features of executive dysfunction in frontotemporal and Alzheimer's dementia. Applied neuropsychology. Adult. 2019:1-15. PubMed PMID: 31424275; PubMed Central PMCID: PMC7028481.

Koo KYG, Schweizer TA, Fischer CE, Munoz DG. Abnormal sleep behaviours across the spectrum of Alzheimer's disease severity: influence of ApoE genotypes and Lewy bodies. Current Alzheimer research. 2019;16(3):243-250. PubMed PMID: 30605058; PubMed Central PMCID: PMC6613208.

Kornak J, Fields J, Kremers W, Farmer S, Heuer HW, Forsberg L, Brushaber D, Rindels A, Dodge H, Weintraub S, Besser L, Appleby B, Bordelon Y, Bove J, Brannelly P, Caso C, Coppola G, Dever R, Dheel C, Dickerson B, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fishman A, Fong J, Foroud T, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant IM, Grossman M, Haley D, Hsiao J, Hsiung R, Huey ED, Irwin D, Jones D, Jones L, Kantarci K, Karydas A, Kaufer D, Kerwin D, Knopman D, Kraft R, Kramer J, Kukull W, Lapid M, Litvan I, Ljubenkov P, Lucente D, Lungu C, Mackenzie I, Maldonado M, Manoochehri M, McGinnis S, McKinley E, Mendez M, Miller B, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin K, Rascovsky K, Roberson ED, Rogalski-Miller E, Sengdy P, Shaw L, Staffaroni AM, Sutherland M, Syrjanen J, Tartaglia C, Tatton N, Taylor J, Toga A, Trojanowski J, Wang P, Wong B, Wszolek Z, Boeve B, Boxer A, Rosen H. Nonlinear z-score modeling for improved detection of cognitive abnormality. Alzheimer's & dementia (Amsterdam, Netherlands). 2019;11:797-808. PubMed PMID: 31872042; PubMed Central PMCID: PMC6911910.

Krejciova Z, Carlson GA, Giles K, Prusiner SB. Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein. Acta neuropathologica communications. 2019;7(1):81. PubMed PMID: 31109379; PubMed Central PMCID: PMC6526619.

Lehallier B, Gate D, Schaum N, Nanasi T, Lee SE, Yousef H, Moran Losada P, Berdnik D, Keller A, Verghese J, Sathyan S, Franceschi C, Milman S, Barzilai N, Wyss-Coray T. Undulating changes in human plasma proteome profiles across the lifespan. Nature medicine. 2019;25(12):1843-1850. PubMed PMID: 31806903; PubMed Central PMCID: PMC7062043.

Leoutsakos JS, Wise EA, Lyketsos CG, Smith GS. Trajectories of neuropsychiatric symptoms over time in healthy volunteers and risk of MCI and dementia. International journal of geriatric psychiatry. 2019;34(12):1865-1873. PubMed PMID: 31452260; PubMed Central PMCID: PMC6854285.

Liew TM. Symptom clusters of neuropsychiatric symptoms in mild cognitive impairment and their comparative risks of dementia: a cohort study of 8530 older persons. Journal of the American Medical Directors Association. 2019;20(8):1054.e1-1054.e9. PubMed PMID: 30926409; PubMed Central PMCID: PMC6663577.

Liew TM. Developing a brief neuropsychological battery for early diagnosis of cognitive impairment. Journal of the American Medical Directors Association. 2019;20(8):1054.e11-1054.e20. PubMed PMID: 30992186; PubMed Central PMCID: PMC6663638.

Liew TM. The optimal short version of Montreal Cognitive Assessment in diagnosing mild cognitive impairment and dementia. Journal of the American Medical Directors Association. 2019;20(8):1055.e1-1055.e8. PubMed PMID: 30910550; PubMed Central PMCID: PMC6663597.

Liew TM. Depression, subjective cognitive decline, and the risk of neurocognitive disorders. Alzheimer's research & therapy. 2019;11(1):70. PubMed PMID: 31399132; PubMed Central PMCID: PMC6689179.

Ma Y, Jun GR, Chung J, Zhang X, Kunkle BW, Naj AC, White CC, Bennett DA, De Jager PL, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GD, Farrer LA, Lunetta KL. CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease. Aging cell. 2019;18(4):e12964. PubMed PMID: 31144443; PubMed Central PMCID: PMC6612647.

Milani SA, Marsiske M, Striley CW. Discriminative ability of Montreal Cognitive Assessment subtests and items in racial and ethnic minority groups. Alzheimer disease and associated disorders. 2019;33(3):226-232. PubMed PMID: 31058685; PubMed Central PMCID: PMC6710139.

Minhas PS, Liu L, Moon PK, Joshi AU, Dove C, Mhatre S, Contrepois K, Wang Q, Lee BA, Coronado M, Bernstein D, Snyder MP, Migaud M, Majeti R, Mochly-Rosen D, Rabinowitz JD, Andreasson KI. Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation. Nature immunology. 2019;20(1):50-63. PubMed PMID: 30478397; PubMed Central PMCID: PMC6768398.

Mrdjen D, Fox EJ, Bukhari SA, Montine KS, Bendall SC, Montine TJ. The basis of cellular and regional vulnerability in Alzheimer's disease. Acta neuropathologica. 2019;138(5):729-749. PubMed PMID: 31392412; PubMed Central PMCID: PMC6802290.

Moloney M, Oh G, Moga DC. Determinants of sleep medication use among participants in the National Alzheimer's Coordinating Center uniform data set. Journal of applied gerontology: the official journal of the Southern Gerontological Society. 2019:733464819888447. PubMed PMID: 31747852; PubMed Central PMCID: PMC7237298.

Nance C, Ritter A, Miller JB, Lapin B, Banks SJ. The pathology of rapid cognitive decline in clinically diagnosed Alzheimer's disease. Journal of Alzheimer's disease: JAD. 2019;70(4):983-993. PubMed PMID: 31306127; PubMed Central PMCID: PMC7306887.

Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Chui HC, Fardo DW, Flanagan ME, Halliday G, Hokkanen SRK, Hunter S, Jicha GA, Katsumata Y, Kawas CH, Keene CD, Kovacs GG, Kukull WA, Levey AI, Makkinejad N, Montine TJ, Murayama S, Murray ME, Nag S, Rissman RA, Seeley WW, Sperling RA, White Iii CL, Yu L, Schneider JA. Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report. Brain: a journal of neurology. 2019;142(6):1503-1527. PubMed PMID: 31039256; PubMed Central PMCID: PMC6536849.

Oh G, Abner EL, Fardo DW, Freeman PR, Moga DC. Patterns and predictors of chronic opioid use in older adults: a retrospective cohort study. PloS one. 2019;14(1):e0210341. PubMed PMID: 30633773; PubMed Central PMCID: PMC6329525.

Ouyang J, Chen KT, Gong E, Pauly J, Zaharchuk G. Ultra-low-dose PET reconstruction using generative adversarial network with feature matching and task-specific perceptual loss. Medical physics. 2019;46(8):3555-3564. PubMed PMID: 31131901; PubMed Central PMCID: PMC6692211.

Perales-Puchalt J, Gauthreaux K, Flatt J, Teylan MA, Resendez J, Kukull WA, Chan KCG, Burns J, Vidoni ED. Risk of dementia and mild cognitive impairment among older adults in same-sex relationships. International journal of geriatric psychiatry. 2019;34(6):828-835. PubMed PMID: 30864178; PubMed Central PMCID: PMC6502266.

Peterson B, Armstrong M, Galasko D, Galvin JE, Goldman J, Irwin D, Paulson H, Kaufer D, Leverenz J, Lunde A, McKeith IG, Siderowf A, Taylor A, Amodeo K, Barrett M, Domoto-Reilly K, Duda J, Gomperts S, Graff-Radford N, Holden S, Honig L, Huddleston D, Lippa C, Litvan I, Manning C, Marder K, Moussa C, Onyike C, Pagan F, Pantelyat A, Pelak V, Poston K, Quinn J, Richard I, Rosenthal LS, Sabbagh M, Scharre D, Sha S, Shill H, Torres-Yaghi Y, Christie T, Graham T, Richards I, Koehler M, Boeve B. Lewy Body Dementia Association's research centers of excellence program: inaugural meeting proceedings. Alzheimer's research & therapy. 2019;11(1):23. PubMed PMID: 30867052; PubMed Central PMCID: PMC6417280.

Petkus AJ, Resnick SM, Rapp SR, Espeland MA, Gatz M, Widaman KF, Wang X, Younan D, Casanova R, Chui H, Barnard RT, Gaussoin S, Goveas JS, Hayden KM, Henderson VW, Sachs BC, Saldana S, Shadyab AH, Shumaker SA, Chen JC. General and domain-specific cognitive reserve, mild cognitive impairment, and dementia risk in older women. Alzheimer's & dementia (New York, N. Y.). 2019;5:118-128. PubMed PMID: 31011622; PubMed Central PMCID: PMC6461572.

Puzo C, Labriola C, Sugarman MA, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Stein TD, Kowall NW, McKee AC, Mez J, Killiany RJ, Stern RA, Alosco ML. Independent effects of white matter hyperintensities on cognitive, neuropsychiatric, and functional decline: a longitudinal investigation using the National Alzheimer's Coordinating Center Uniform Data Set. Alzheimer's research & therapy. 2019;11(1):64. PubMed PMID: 31351489; PubMed Central PMCID: PMC6661103.

Quintas-Neves M, Teylan MA, Besser L, Soares-Fernandes J, Mock CN, Kukull WA, Crary JF, Oliveira TG. Magnetic resonance imaging brain atrophy assessment in primary age-related tauopathy (PART). Acta neuropathologica communications. 2019;7(1):204. PubMed PMID: 31818331; PubMed Central PMCID: PMC6902469.

Ruthirakuhan M, Herrmann N, Vieira D, Gallagher D, Lanctôt KL. The roles of apathy and depression in predicting Alzheimer disease: a longitudinal analysis in older adults with mild cognitive impairment. The American journal of geriatric psychiatry: official journal of the American Association for Geriatric Psychiatry. 2019;27(8):873-882. PubMed PMID: 30910421; PubMed Central PMCID: PMC6646066.

Sha SJ, Deutsch GK, Tian L, Richardson K, Coburn M, Gaudioso JL, Marcal T, Solomon E, Boumis A, Bet A, Mennes M, van Oort E, Beckmann CF, Braithwaite SP, Jackson S, Nikolich K, Stephens D, Kerchner GA, Wyss-Coray T. Safety, tolerability, and feasibility of young plasma infusion in the plasma for Alzheimer symptom amelioration study: a randomized clinical trial. JAMA neurology. 2019;76(1):35-40. PubMed PMID: 30383097; PubMed Central PMCID: PMC6439869.

Shahid M, Kim J, Leaver K, Hendershott T, Zhu D, Cholerton B, Henderson VW, Tian L, Poston KL. An increased rate of longitudinal cognitive decline is observed in Parkinson's disease patients with low CSF Aß42 and an APOE ε4 allele. Neurobiology of disease. 2019;127:278-286. PubMed PMID: 30826425; PubMed Central PMCID: PMC6588475.

Shinall MC Jr, Hoskins A, Hawkins AT, Bailey C, Brown A, Agarwal R, Duggan MC, Beskow LM, Periyakoil VS, Penson DF, Jarrett RT, Chandrasekhar R, Ely EW. A randomized trial of a specialist palliative care intervention for patients undergoing surgery for cancer: rationale and design of the Surgery for Cancer with Option of Palliative Care Expert (SCOPE) Trial. Trials. 2019;20(1):713. PubMed PMID: 31829237; PubMed Central PMCID: PMC6907134

Sørensen TT, Horváth-Puhó E, Nørgaard M, Ehrenstein V, Henderson VW. Risk of amyotrophic lateral sclerosis and other motor neuron disease among men with benign prostatic hyperplasia: a population-based cohort study. BMJ open. 2019;9(7):e030015. PubMed PMID: 31278107; PubMed Central PMCID: PMC6615877.

Spangler-Bickell MG, Khalighi MM, Hoo C, DiGiacomo PS, Maclaren J, Aksoy M, Rettmann D, Bammer R, Zaharchuk G, Zeineh M, Jansen F. Rigid motion correction for brain PET/MR imaging using optical tracking. IEEE transactions on radiation and plasma medical sciences. 2019;3(4):498-503. PubMed PMID: 31396580; PubMed Central PMCID: PMC6686883.

Sriprasert I, Hodis HN, Karim R, Stanczyk FZ, Shoupe D, Henderson VW, Mack WJ. Differential effect of plasma estradiol on subclinical atherosclerosis progression in early vs late postmenopause. The Journal of clinical endocrinology and metabolism. 2019;104(2):293-300. PubMed PMID: 30272234; PubMed Central PMCID: PMC6300071.

Stasenko A, Jacobs DM, Salmon DP, Gollan TH. The Multilingual Naming Test (MINT) as a measure of picture naming ability in Alzheimer's disease. Journal of the International Neuropsychological Society: JINS. 2019;25(8):821-833. PubMed PMID: 31248465; PubMed Central PMCID: PMC6757330.

Sugarman MA, McKee AC, Stein TD, Tripodis Y, Besser LM, Martin B, Palmisano JN, Steinberg EG, O'Connor MK, Au R, McClean M, Killiany R, Mez J, Weiner MW, Kowall NW, Stern RA, Alosco ML. Failure to detect an association between self-reported traumatic brain injury and Alzheimer's disease neuropathology and dementia. Alzheimer's & dementia: the journal of the Alzheimer's Association. 2019;15(5):686-698. PubMed PMID: 30852157; PubMed Central PMCID: PMC6511462.

Sundaram S, Müller-Oehring EM, Fama R, Brontë-Stewart HM, Poston KL, Goodcase R, Martin T, Prabhakar V, Karpf J, Schulte T. Information processing deficit in older adults with HIV infection: A comparison with Parkinson's disease. Neuropsychology. 2019;33(2):157-168. PubMed PMID: 30475047; PubMed Central PMCID: PMC7372910.

Teylan M, Besser LM, Crary JF, Mock C, Gauthreaux K, Thomas NM, Chen YC, Kukull WA. Clinical diagnoses among individuals with primary age-related tauopathy versus Alzheimer's neuropathology. Laboratory investigation; a journal of technical methods and pathology. 2019;99(7):1049-1055. PubMed PMID: 30710118; PubMed Central PMCID: PMC6609478.

Tran QNH, Dieu-Hien HT, King IN, Sheehan K, Iglowitz ML, Periyakoil VS. Providing culturally respectful care for seriously ill Vietnamese Americans. Journal of pain and symptom management. 2019;58(2):344-354. PubMed PMID: 30922704; PubMed Central PMCID: PMC7310713.

Trotter JH, Hao J, Maxeiner S, Tsetsenis T, Liu Z, Zhuang X, Südhof TC. Synaptic neurexin-1 assembles into dynamically regulated active zone nanoclusters. The journal of cell biology. 2019;218(8):2677-2698. PubMed PMID: 31262725; PubMed Central PMCID: PMC6683742.

Vöglein J, Paumier K, Jucker M, Preische O, McDade E, Hassenstab J, Benzinger TL, Noble JM, Berman SB, Graff-Radford NR, Ghetti B, Farlow MR, Chhatwal J, Salloway S, Xiong C, Karch CM, Cairns N, Mori H, Schofield PR, Masters CL, Goate A, Buckles V, Fox N, Rossor M, Chrem P, Allegri R, Ringman JM, Höglinger G, Steiner H, Dieterich M, Haass C, Laske C, Morris JC, Bateman RJ, Danek A, Levin J. Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease. Brain: a journal of neurology. 2019;142(5):1429-1440. PubMed PMID: 30897203; PubMed Central PMCID: PMC6735903.

Wang Y, Haaksma ML, Ramakers IHGB, Verhey FRJ, van de Flier WM, Scheltens P, van Maurik I, Olde Rikkert MGM, Leoutsakos JS, Melis RJF. Cognitive and functional progression of dementia in two longitudinal studies. International journal of geriatric psychiatry. 2019;34(11):1623-1632. PubMed PMID: 31318090; PubMed Central PMCID: PMC6803041.

Werry AE, Daniel M, Bergström B. Group differences in normal neuropsychological test performance for older non-Hispanic White and Black/African American adults. Neuropsychology. 2019;33(8):1089-1100. PubMed PMID: 31343234; PubMed Central PMCID: PMC6823108.

Wingo TS, Cutler DJ, Wingo AP, Le NA, Rabinovici GD, Miller BL, Lah JJ, Levey AI. Association of early-onset Alzheimer disease with elevated low-density lipoprotein cholesterol levels and rare genetic coding variants of ApoE. JAMA neurology. 2019;76(7):809-817. PubMed PMID: 31135820; PubMed Central PMCID: PMC6547122.

Wise EA, Rosenberg PB, Lyketsos CG, Leoutsakos JM. Time course of neuropsychiatric symptoms and cognitive diagnosis in National Alzheimer's Coordinating Centers volunteers. Alzheimer's & dementia (Amsterdam, Netherlands). 2019;11:333-339. PubMed PMID: 31024987; PubMed Central PMCID: PMC6476801.

2018

Askari N, Bilbrey AC, Garcia Ruiz I, Humber MB, Gallagher-Thompson D.  Dementia awareness campaign in the Latino community: a novel community engagement pilot program with promotoras. Clinical Gerontologist. 2018;41(3):200-208. PMID:29240536; PMCID: PMC5935246.

Bagge CN, Henderson VW, Laursen HB, Adelborg K, Olsen M, Madsen NL. Risk of dementia in adults with congenital heart disease: Population-based cohort study. Circulation. 2018;137(2):1912-1920. PMID: 29440121; PMCID: PMC5930034.

Barnes J, Bartlett JW, Wolk DA, van der Flier WM, Frost C. Disease course varies according to age and symptom length in Alzheimer’s disease. Journal of Alzheimer’s Disease. 2018;64(2):631-642. PMID: 29914016; PMCID: PMC6207933.

Bennett FC, Bennett ML, Yaqoob F, Mulinyawe SB, Grant GA, Hayden GM, Plowey ED, Barres BA. A Combination of ontogeny and CNS environment establishes microglial identity. Neuron. 2018;98(6) :1170-1183.e8. PMID: 29861285; PMCID: PMC6023731. 

Bharadwaj R, Cimino PJ, Flanagan ME, Latimer CS, Gonzalez-Cuyar LF, Juric-Sekhar G, Montine TJ, Marshall DA, Keene CD. Application of the condensed protocol for the NIA-AA guidelines for the neuropathological assessment of Alzheimer’s disease in an academic clinical practice. Histopathology. 2018;72(3):433-440. PMID: 28815699; PMCID: PMC5771846.

Bilbrey AC, Humber MB, Plowey ED, Garcia I, Chennapragada L, Desai K, Rosen A, Askari N, Gallagher-Thompson D.  The impact of Latino values and cultural beliefs on brain donation: Results of a pilot study to develop culturally appropriate materials and methods to increase rates of brain donation in this under-studied patient group. Clinical Gerontologist. 2018;41(3):237-248. PMID: 29227743; PMCID: PMC5962259.

Brenowitz WD, Han F, Kukull WA, Nelson PT. Treated hypothyroidism is associated with cerebrovascular disease but not Alzheimer's disease pathology in older adults. Neurobiology of Aging. 2018 02; 62 :64-71. PMID: 29107848: PMCID: PMC5743774. 

Burke SL, Cadet T, Maddux M. Chronic health illnesses as predictors of mild cognitive impairment among African American older adults. Journal of the National Medical Association. 2018;110(4):314-325. PMID: 30126555; PMCID: PMC6108440.

Burke SL, Hu T, Fava NM, Li T, Rodriguez MJ, Schuldiner KL, Burgess A, Laird A. Sex differences in the development of mild cognitive impairment and probable Alzheimer's disease as predicted by hippocampal volume or white matter hyperintensities. Journal of Women & Aging. 2018:1-25. PMID: 29319430; PMCID: PMC6039284.

Burke SL, Maramaldi P, Cadet T, Kukull W. Decreasing hazards of Alzheimer's disease with the use of antidepressants: mitigating the risk of depression and apolipoprotein E.  International Journal of Geriatric Psychiatry. 2018;33(1):200-211. PMID: 28560728; PMCID: PMC5711617.

Clark, JL; Phoenix S, Bilbrey, AC; McManis, T, Escal KA, Arulanantham R, Sisay T, Ghatak R. Cultural Competency in dementia care: An African American case study. Clinical Gerontologist. 2018;41(3):255-260. PMID: 29338663; PMCID: PMC5962259. 

Cocoros NM, Ording AG, Horváth-Puhó E, Henderson VW, Sørensen HT. In utero exposure to the 1918 pandemic influenza in Denmark and risk of dementia. Influenza and Other Respiratory Viruses. 2018;12(3):314-318. PMID: 29356338; PMCID: PMC5907820.

Crum J, Wilson J, Sabbagh M. Does taking statins affect the pathological burden in autopsy-confirmed Alzheimer’s dementia? Alzheimer’s Research & Therapy. 2018;10(1):104. PMID: 30285877; PMCID: PMC6169006.

Flanagan, ME, Keene CD, Louis DN, Juric‐Sekhar G. Localized crystal-storing histiocytosis of the posterior fossa.  Neuropathology. 2018;38(5):529-534. PMID: 30066398; PMCID: PMC 6172157.

Flanagan ME, Larson EB, Walker RL, Keene CD, Postupna N, Cholerton B, Sonnen JA, Dublin S, Crane PK, Montine TJ. Associations between use of specific analgesics and concentrations of amyloid-β 42 or phospho-tau in regions of human cerebral cortex. Journal of Alzheimer’s Disease. 2018;61(2):653-662. PMID: 29226863; PMCID: PMC5745256.

Gallagher D, Kiss A, Lanctot K, Herrmann, N.  Depression and risk of Alzheimer dementia: A longitudinal analysis to determine predictors of increased risk among older adults with depression. American Journal of Geriatric Psychiatry. 2018;26(8):819-827. PMID: 29960668; PMCID: PMC6101977.

Ge T, Sabuncu MR, Smoller JW, Sperling RA, Mormino EC; Alzheimer's Disease Neuroimaging Initiative. Dissociable influences of ApoE ε4 and polygenic risk of AD dementia on amyloid and cognition. Neurology. 2018;90(18):e1605-e1612. PMID: 29592889; PMCID: PMC5931806.

Haaksma ML, Calderón-Larrañaga A, Olde R, Marcel GM; Melis RJF, Leoutsakos JMS. Cognitive and functional progression in Alzheimer’s disease: a prediction model of latent classes. International Journal of Geriatric Psychiatry. 2018;33(8):1057-1064.  PMID: 29761569: PMCID: PMC6039270.

Hadjichrysanthou C, McRae-McKee K, Evans S, de Wolf F, Anderson RM; Alzheimer’s Disease Neuroimaging Initiative. Potential factors associated with cognitive improvement of individuals diagnosed with mild cognitive impairment or dementia in longitudinal studies. Journal of Alzheimer’s Disease. 2018;66(2):587-600. PMID: 30320573; PMCID: PMC6218131.

Hanfelt JJ, Peng L, Goldstein FC, Lah JJ. Latent classes of mild cognitive impairment are associated with clinical outcomes and neuropathology: analysis of data from the National Alzheimer's Coordinating Center. Neurobiology of Disease. 2018;117:62-71. PMC: 29859866; PMCID: PMC6093304.

Harvey ZH, Chen Y, Jarosz DF. Protein-based inheritance: Epigenetics beyond the chromosome. Molecular Cell. 2018;69(2):195-202. PMID: 29153393; PMCID: PMC5775936.

Kamara DM, Gangishetti U, Gearing M, Willis-Parker M, Zhao L, Hu WT, Walker LC. Cerebral amyloid angiopathy: Similarity in African-Americans and Caucasians with Alzheimer’s disease. Journal of Alzheimer’s disease. 2018:62(4):1815-1826. PMID: 29614657; PMCID: PMC6103628.

Kaur A, Edland SD, Peavy GM. The MoCA-memory index score: an efficient alternative to paragraph recall for the detection of amnestic mild cognitive impairment. Alzheimer Disease and Associated Disorders. 2018;32(2):120-124. PMID: 29319601; PMCID: PMC5963962.

Kirson NY, Scott Andrews J, Desai U, King SB, Schonfeld S, Birnbaum HG, Ball DE, Kahle-Wrobleski K. Patient characteristics and outcomes associated with receiving an earlier versus later diagnosis of probable Alzheimer’s disease. Journal of Alzheimer’s Disease. 2018;61(1):295-307. PMID:29154268; PMCID: PMC5734126.

Lin, M, Gong, P, Yang, T, Ye, J, Albin, RL, Dodge, HH. Big data analytical approaches to the NACC dataset: aiding preclinical trial enrichment. Alzheimer Disease and Associated Disorders. 2018;32(1):18-27. PMID: 29227306; PMCID: PMC5854492.

Qiu S, Chang GH, Panagia M, Gopal DM, Au R, Kolachalama VB. Fusion of deep learning models of MRI scans, Mini-Mental State Examination, and logical memory test enhances diagnosis of mild cognitive impairment. Alzheimer’s & Dementia. 2018;10:737-749. PMID: 30480079; PMCID: PMC6240705.

Schaffert J, LoBue C, White CL, Chiang HS, Didehbani N, Lacritz L, Rossetti H, Dieppa M, Hart J, Cullum CM.  Traumatic brain injury history is associated with an earlier age of dementia onset in autopsy-confirmed Alzheimer's disease. Neuropsychology. 2018:32(4):410-416. PMID:29389151; PMCID: PMC5975092.

Sclesi MA, Khan RR, Lorenzi M, Chrisopher L, Greicius MD, Schott JM, Ourselin S, Altmann A: Genetic study of multimodal imaging Alzheimer’s disease progression score implicates novel loci. Brain. 2018; 141:2167-2180. PMID:29860282; PMCID: PMC6022660.

Smith AK, Periyakoil VS. Should we bury "The Good Death"?  Journal of the American Geriatrics Society. 2018;66(5):856-858. PMID: 29508391; PMCID: PMC5992042.

Svensson E, Henderson VW, Szépligeti S, Stokholm MG, Klug TE, Sørensen HT, Borghammer P. Tonsillectomy and risk of Parkinson ‘s disease: a Danish nationwide population-based cohort study. Movement Disorders. 2018;33(2):321-324. PMID: 29193401; PMCID: PMC5809198.

Ting SKS, Foo H, Chia PS, Hameed S, Ng KP, Ng A, Kandiah N.  Dyslexic characteristics of Chinese-speaking semantic variant of primary progressive aphasia. Journal of Neuropsychiatry and Clinical Neurosciences. 2018;30(1):31-37. PMID: 29061089; PMCID: PMC5794526.

Tse KH, Cheng A, Ma F, Herrup K. DNA damage-associated oligodendrocyte degeneration precedes amyloid pathology and contributes to Alzheimer's disease and dementia. Alzheimer's & Dementia. 2018;14(5):664-679.  PMID:29328926; PMCID: PMC5938117.  

Turk KW, Flanagan ME, Josephson S, Keene CD, Jayadev S, Bird TD. Psychosis in spinocerebellar ataxias: a case series and study of tyrosine hydroxylase in substantia nigra. Cerebellum. 2018;17(2):143-151. PMID: 28887803; PMCID: PMC5843512.

Wang T, Qiu RG,Yu M.  Predictive modeling of the progression of Alzheimer’s disease with recurrent neural networks. Scientific Reports. 2018;8(1):9161. PMC: 29907747; PMCID: PMC6003986.

Weintraub S, Besser L, Dodge HH, Teylan M, Ferris S, Goldstein FC, Giordani B, Kramer J, Loewenstein D, Marson D, Mungas D, Salmon D, Welsh-Bohmer K, Zhou XH, Shirk SD, Atri A, Kukull WA, Phelps C, Morris JC. Version 3 of the Alzheimer Disease Centers & ApoE neuropsychological test battery in the Uniform Data Set (UDS). Alzheimer Disease and Associated Disorders. 2018;32(1):10-17. PMID: 29240561; PMCID: PMC5821520.

Wilmoth K, LoBue C, Clem MA, Reddy R, Hynan LS, Didehbani N, Bell K, Womack KB, Hart Jr J, Batjer H, Cullum CM.  Consistency of traumatic brain injury reporting in older adults with and without cognitive impairment.  Clinical Neuropsychologist. 2018;32(3):524-529. PMID: 28988512; PMCID: PMC5851823.

2017

Alagappan M, Richardson MT, Schoen MK, Muffly L, Tierney K, Jenkins P, Neri E, Kraemer HC, Periyakoil VS. A three-step letter advance directive procedure to facilitate patient-proxy alignment in advance care planning. Journal of palliative medicine. 2018;21(12):1749-1754. PubMed PMID: 30247088; PubMed Central PMCID: PMC6308271.

Adelborg K, Horváth-Puhó E, Ording A, Pedersen L, Toft Sørensen H, Henderson VW. Heart failure and risk of dementia: a Danish nationwide population-based cohort study. European Journal of Heart Failure. 2017;19(2):253-260. PMID: 27612177; PMCID: PMC5522185.

Beaudreau SA, Hantke NC, Mashal N, Gould CE, Henderson VW, O'Hara, R. Unlocking neurocognitive substrates of late-life affective symptoms using the research domain criteria: worry is an essential dimension. Frontiers of Aging Neuroscience. 2017;9:380. PMID: 29249958; PMCID: PMC5715397.

Bernier PJ, Gourdeau C, Carmichael PH, Beauchemin JP, Verreault R,  Bouchard RW, Kröger E, Laforce Jr R. Validation and diagnostic accuracy of predictive curves of age-associated longitudinal cognitive decline in older adults. Canadian Medical Association journal. 2017;189(48):E1472-E1480. PMID: 29203616; PMCID: PMC5714699.

Boise L, Hinton L, Rosen HJ, Ruhl MC, Dodge H, Mattek N, Albert M, Denny A, Grill JD, Hughes T, Lingler JH, Morhardt D, Parfitt F, Peterson-Hazan S, Pop V, Rose T, Shah RC. Willingness to be a brain donor: a survey of research volunteers from 4 racial/ethnic groups. Alzheimer Disease and Associated Disorders. 2017;31(2):135-140. PMID: 27779492; PMCID: PMC5403614.

Brenowitz WD, Hubbard RA, Keene CD, Hawes SE, Longstreth WT Jr, Woltjer RL, Kukull WA. Mixed neuropathologies and estimated rates of clinical progression in a large autopsy sample. Alzheimer’s Dement. 2017;13(6):654-662. PMID: 27870939; PMCID: PMC5438283.

Brenowitz WD, Keene CD, Hawes SE, Hubbard RA, Longstreth WT Jr., Woltjer RL, Crane PK, Larson EB, Kukull WA. Alzheimer’s disease neuropathologic change, Lewy body disease, and vascular brain injury in clinic- and community-based samples. Neurobiology of Aging. 2017;53:83-92. PMID: 28236716; PMCID: PMC5385292.

Burke SL, O'Driscoll J, Alcide A, Li T. Moderating risk of Alzheimer's disease through the use of anxiolytic agents. International Journal of Geriatric Psychiatry. 2017;32(12):1312-1321. PMID: 27805724; PMCID: PMC5441966.

Castellano JM, Mosher KI, Abbey RJ, McBride AA, James ML, Berdnik D, Shen JC, Zou B, Xie XS, Tingle M, Hinkson IV, Angst MS, Wyss-Coray T. Human umbilical cord plasma proteins revitalize hippocampal function in aged mice. Nature. 2017;544(7651):488-492. PMID: 28424512; PMCID: PMC5586222.

Christopher L, Napolioni V, Khan RR, Han SS, Greicius MD. A variant in PPP4R3A protects against Alzheimer-related metabolic decline. Annals of Neurology. 2017;82(6):900-911. PMID: 29130521; PMCID: PMC5752155.

Corces MR, Trevino AE, Hamilton EG, Greenside PG, Sinnott-Armstrong NA, Vesuna S, Satpathy AT, Rubin AJ, Montine KS, Wu B, Kathiria A, Cho SW, Mumbach MR, Carter AC, Kasowski M, Orloff LA, Risca VI, Kundaje A, Khavari PA, Montine TJ, Greenleaf WJ, Chang HY. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nature Methods. 2017;14(10):959-962. PMID: 28846090; PMCID: PMC5623106.

Czirr E, Castello NA, Mosher KI, Castellano JM, Hinkson IV, Lucin KM, Baeza-Raja B, Ryu JK, Li L, Farina SN, Belichenko NP, Longo FM, Akassoglou K, Britschgi M, Cirrito JR, Wyss-Coray T. Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity. Journal of Experimental Medicine. 2017;214(4):1081-1092. PMID: 28298456; PMCID: PMC5379986.

Flanagan ME, Marshall DA, Shofer JB, Montine KS, Nelson PT, Montine TJ, Keene CD. Performance of a condensed protocol that reduces effort and cost of NIA-AA guidelines for neuropathologic assessment of Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 2017;76(1):39-43. PMID: 28062571; PMCID: PMC6251587.

Goldstein FC, Steenland K, Zhao L, Wharton W, Levey AI, Hajjar I. Proton pump inhibitors and risk of mild cognitive impairment and dementia. Journal of the American Geriatrics Society. 2017;65(9):1969-1974.  PMID: 28590010; PMCID: PMC5797939.

Hendershott TR, Zhu D, Llanes S, Poston KL. Domain-specific accuracy of the Montreal cognitive assessment subsections in Parkinson’s disease. Parkinsonism & Related Disorders. 2017:38:31-34. PMID: 28215728; PMCID: PMC5400012.

Jefferson-George KS, Wolk DA, Lee EB, McMillan CT. Cognitive decline associated with pathological burden in primary age-related tauopathy. Alzheimer’s & Dementia. 2017;13(9):1048-1053. PMID: 28322204; PMCID: PMC5585025.

Jutkowitz E, Kane RL, Gaugler JE, MacLehose RF, Dowd B, Kuntz KM. Societal and family lifetime cost of dementia: implications for policy. Journal of the American Geriatrics Society. 2017;65(10):2169-2175. PMID: 28815557; PMCID: PMC5657516.

Jutkowitz E, MacLehose RF, Gaugler JE, Dowd B, Kuntz KM, Kane RL. Risk factors associated with cognitive, functional, and behavioral trajectories of newly diagnosed dementia patients. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2017;72(2):251-258. PMID: 27129917; PMCID: PMC5344797.

Katsumata Y, Nelson PT, Ellingson SR, Fardo DW. Gene-based association study of genes linked to hippocampal sclerosis of aging neuropathology: GRN, TMEM106B, ABCC9, and KCNMB2. Neurobiology of Aging. 2017;53:193.e17-193.e25. PMID: 28131462; PMCID: PMC5385271.

Kim J, Schweizer TA, Fischer CE, Munoz DG. The role of cerebrovascular disease on cognitive and functional status and psychosis in severe Alzheimer’s disease. Journal of Alzheimer & ApoE disease. 2017;55(1):381-389. PMID: 27662301; PMCID: PMC5115606.

Lange C, Suppa P,  Mäurer A, Ritter K, Pietrzyk U, Steinhagen-Thiessen E,  Fiebach JB, Spies L, Buchert R. Mental speed is associated with the shape irregularity of white matter MRI hyperintensity load. Brain Imaging and Behavior. 2017;11(6):1720-1730. PMID: 27796731; PMCID: PMC5843991.

Latimer CS, Keene CD, Flanagan ME, Hemmy LS, Lim KO, White LR, Montine KS, Montine TJ. Resistance to Alzheimer disease neuropathologic changes and apparent cognitive resilience in the nun and Honolulu-Asia aging studies. Journal of Neuropathology and Experimental Neurology. 2017;76(6):458-466. PMID: 28499012.

Lim YY, Mormino EC; Alzheimer's Disease Neuroimaging Initiative. ApoE genotype and early β-amyloid accumulation in older adults without dementia. Neurology. 2017;89(10):1028-1034. PMID: 28794245; PMCID: PMC5589795.

Mathur V, Burai R, Vest RT, Bonanno LN, Lehallier B, Zardeneta ME, Mistry KN, Do D, Marsh SE, Abud EM, Blurton-Jones M, Li L, Lashuel HA, Wyss-Coray T. Activation of the STING-dependent Type I interferon response reduces microglial reactivity and neuroinflammation. Neuron. 2017;96(6):1290-1302.e6. PMID: 29268096; PMCID: PMC5806703.

Moga DC, Taipale H, Tolppanen AM, Tanskanen A, Tiihonen J, Hartikainen S, Wu Q, Jicha GA, Gnjidic D. A comparison of sex differences in psychotropic medication use in older people with Alzheimer’s disease in the US and Finland. Drugs & Aging. 2017;34(1):55-65. PMID: 27896799; PMCID: PMC5253689.

Moga DC, Abner EL, Wu Q, Jicha GA. Bladder antimuscarinics and cognitive decline in elderly patients. Alzheimer’s & Dementia. 2017;3(1):139-148. PMID: 28462390; PMCID: PMC5408467.

Moheb N, Mendez MF, Kremen SA, Teng E. Executive dysfunction and behavioral symptoms are associated with deficits in instrumental activities of daily living in frontotemporal dementia. Dementia and Geriatric Cognitive Disorders. 2017;43(1-2):89-99. PMID: 28103593; PMCID: PMC5300022.

Montgomery V, Harris K, Stabler A, Lu LH. Effects of delay duration on the WMS logical memory performance of older adults with probable Alzheimer’s disease, probable vascular dementia, and normal cognition. Archives of Clinical Neuropsychology. 2017;32(3):375-380. PMID: 28431036; PMCID: PMC5400025.

Neu SC, Pa J, Kukull W, Beekly D, Kuzma A, Gangadharan P, Wang LS, Romero K, Arneric SP, Redolfi A, Orlandi D, Frisoni GB, Au R, Devine S, Auerbach S, Espinosa A, Boada M, Ruiz A, Johnson SC, Koscik R, Wang JJ, Hsu WC, Chen YL, Toga AW. Apolipoprotein E genotype and sex risk factors for Alzheimer disease: a meta-analysis. JAMA Neurology. 2017;74(10):1178-1189. PMID: 28846757; PMCID: PMC5759346.

Ng B, Varoquaux G, Poline JB, Thirion B, Greicius MD, Poston KL. Distinct alterations in Parkinson’s medication-state and disease-state connectivity. NeuroImage. Clinical. 2017;16:575-585. PMID: 28971008; PMCID: PMC5608603.

Pandya SY, Lacritz LH, Weiner MF, Deschner M, Woon FL. Predictors of reversion from mild cognitive impairment to normal cognition. Dementia and Geriatric Cognitive Disorders. 2017;43(3-4):204-214. PMID: 28301848; PMCID: PMC5495561.

Postupna N, Latimer CS, Larson EB, Sherfield E, Paladin J, Shively CA, Jorgensen MJ, Andrews RN, Kaplan JR, Crane PK, Montine KS, Craft S, Keene CD, Montine TJ. Human striatal dopaminergic and regional serotonergic synaptic degeneration with Lewy Body Disease and inheritance of APOE ε4. American Journal of Pathology. 2017;187(4): 884-895. PMID: 28212814; PMCID: PMC5397713.

Ramsey CM, Gnjidic D, Agogo GO, Allore H, Moga D. Longitudinal patterns of potentially inappropriate medication use following incident dementia diagnosis. Alzheimer’s & Dementia. 2017;4:1-10. PMID: 29296658; PMCID: PMC5738721.

Ritter AR, Leger GC, Miller JB, Banks SJ. Neuropsychological testing in pathologically verified Alzheimer disease and frontotemporal dementia: How well do the Uniform Data Set measures differentiate between diseases?  Alzheimer Disease and Associated Disorders. 2017;31(3):187-191. PMID: 28005562; PMCID: PMC5479762.

Sano M, Zhu CW, Grossman H, Schimming C. Longitudinal cognitive profiles in diabetes: results from the National Alzheimer's Coordinating Center's Uniform Data. Journal of the American Geriatrics Society. 2017;65(10):2198-2204. PMID: 28771679; PMCID: PMC5641239.

Schmidt SA, Ording AG, Horváth-Puhó E, Sørensen HT, Henderson VW. Non- melanoma skin cancer and risk of Alzheimer’s disease and all-cause dementia. PloS ONE. 2017;12(2): e0171527. PMID: 28225789; PMCID: PMC5321271.

Sennik S, Schweizer TA, Fischer CE, Munoz DG. Risk factors and pathological substrates associated with agitation/aggression in Alzheimer’s disease: A preliminary study using NACC data. Journal of Alzheimer’s Disease. 2017;55(4):1519-1528. PMID: 27911311; PMCID: PMC5607738.

Tchakoute CT, Sainani KL, Henderson VW. Semantic memory in the clinical progression of Alzheimer disease. Cognitive and Behavioral Neurology. 2017;30(3):81-89. PMID: 28926415; PMCID: PMC5617354.

Tripodis Y, Alosco ML, Zirogiannis N, Gavett BE, Chaisson C, Martin B, McClean MD, Mez J, Kowall N, Stern RA. The effect of traumatic brain injury history with loss of consciousness on rate of cognitive decline among older adults with normal cognition and Alzheimer’s disease dementia. Journal of Alzheimer's Disease. 2017;59(1):251-263. PMID: 28655133; PMCID: PMC5614490.

Qian J, Hyman BT, Betensky RA. Neurofibrillary tangle stage and the rate of progression of Alzheimer symptoms: modeling using an autopsy cohort and application to clinical trial design. JAMA Neurology. 2017;74(5):540-548. PMID: 28288263; PMCID: PMC5547572.

2016

Andreasson KI, Bachstetter AD, Colonna M, Ginhoux F, Holmes C, Lamb B, Landreth G, Lee DC, Low D, Lynch MA, Monsonego A, O’Banion MK, Pekny M, Puschmann T, Russek-Blum N, Sandusky LA, Selenica ML, Takata K, Teeling J, Town T, Van Eldik LJ. Targeting innate immunity for neurodegenerative disorders of the nervous system. Journal of Neurochemistry. 2016; 138(5):653-93. PMID: 27248001; PMCID: PMC5433264.

Bonham LW, Geier EG, Fan CC, Leong JK, Besser L, Kukull WA, Kornak J, Andreassen OA, Schellenberg GD, Rosen HJ, Dillon WP, Hess CP, Miller BL, Dale AM, Desikan RS, Yokoyama JS. Age-dependent effects of APOE ε4 in preclinical Alzheimer’s disease. Annals of Clinical and Translational Neurology. 2016;3(9):668-77. PMID: 27648456; PMCID: PMC5018579.

Burke SL, Maramaldi P, Cadet T, Kukull W. Neuropsychiatric symptoms and Apolipoprotein E: associations with eventual Alzheimer’s disease development. Archives of Gerontology and Geriatrics. 2016;65:231-8. PMID: 27111252; PMCID: PMC5029123.

Day GS, Musiek ES, Roe CM, Norton J, Goate AM, Cruchaga C, Cairns NJ, Morris JC. Phenotypic similarities between late-onset autosomal dominant and sporadic Alzheimer disease: a single-family case-control study. JAMA Neurology. 2016;73(9):1125-32. PMID: 27454811; PMCID: PMC5025942.

Henderson VW, St John JA, Hodis HN, McCleary CA, Stanczyk FZ, Shoupe D, Kono N, Dustin L, Allayee H, Mack WJ. Cognitive effects of estradiol after menopause: a randomized trial of the timing hypothesis. Neurology. 2016;87(7):699-708. PMID: 27421538; PMCID: PMC4999165.

Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hoffree M, Huang R, Johns H, Karydas A, Knopman DS, Loboda A, Masliah E, Narasimhan R, Petersen RC, Podtelezhnikov A, Pradhan S, Rademakers R, Sun CH, Younkin SG, Miller BL, Ideker T, Wyss-Coray T. Network-driven plasma proteomics expose molecular changes in the Alzheimer’s brain. Molecular Neurodegeneration. 2016;11:31. PMID: 27112350; PMCID: PMC4845325.

Karim R, Dang H, Henderson VW, Hodis HN, St John J, Brinton RD, Mack WJ. Effect of reproductive history and exogenous hormone use on cognitive function in mid- and late life. Journal of the American Geriatrics Society. 2016;64(12):2448- 2456. PMID: 27996108; PMCID: PMC5180359.

Middeldorp J, Lehallier B, Villeda SA, Miedema SS, Evans E, Czirr E, Zhang H, Luo J, Stan T, Mosher KI, Masliah E, Wyss-Coray T. Preclinical assessment of young blood plasma for Alzheimer disease. JAMA Neurology. 2016;73(11):1325-1333. PMID: 27598869; PMCID: PMC5172595.

Nead KT, Gaskin G, Chester C, Swisher-McClure S, Dudley JT, Leeper NJ, Shah NH. Androgen deprivation therapy and future Alzheimer’s disease risk. Journal of Clinical Oncology. 2016;34(6):566-71. PMID: 26644522; PMCID: PMC5070576.

Nead KT, Gaskin G, Chester C, Swisher-McClure S, Dudley JT, Leeper NJ, Shah NH. Influence of age on androgen deprivation therapy-associated Alzheimer’s disease. Scientific Reports. 2016;6:35695. PMID: 27752112; PMCID: PMC5067668.

Plowey ED, Ziskin JL. Hippocampal phospho-tau/MAPT neuropathology in the fornix in Alzheimer disease: an immunohistochemical autopsy study. Acta Neuropathologica Communications. 2016;4(1):114. PMID: 27793193; PMCID: PMC5086039.

Poston KL, YorkWilliams S, Zhang K, Cai W, Everling D, Tayim FM, Llanes S, Menon V. Compensatory neural mechanisms in cognitively unimpaired Parkinson disease. Annals of Neurology. 2016;79(3):448-63. PMID: 26696272; PMCID: PMC4789131.

Rettberg JR, Dang H, Hodis HN, Henderson VW, St John JA, Mack WJ, Brinton RD. Identifying postmenopausal women at risk for cognitive decline within a healthy cohort using a panel of clinical metabolic indicators: potential for detecting an at-Alzheimer’s risk metabolic phenotype. Neurobiology of Aging. 2016;40:155-63. PMID: 26973115; PMCID: PMC4921204.

Simmons DA, Belichenko NP, Ford EC, Semaan S, Monbureau M, Aiyaswamy S, Holman CM, Condon C, Shamloo M, Massa SM, Longo FM. A small molecule p75NTR ligand normalizes signaling and reduces Huntington’s disease phenotypes in R6/2 and BACHD mice. Human Molecular Genetics. 2016;25(22):4920- 4938. PMID: 28171570; PMCID: PMC5418739.

Warden C, Hwang J, Marshall A, Fenesy M, Poston KL. The effects of dopamine on digit span in Parkinson’s disease. Journal of Clinical Movement Disorders. 2016;3:5. PMID: 26955482; PMCID: PMC4780147.

Woodling NS, Andreasson KI. Untangling the web: Toxic and protective effects of neuroinflammation and PGE2 signaling in Alzheimer’s disease. ACS Chemical Neuroscience. 2016;7(4):454-63. PMID: 26979823; PMCID: PMC5239037.

Woodling NS, Colas D, Wang Q, Minhas P, Panchal M, Liang X, Mhatre SD, Brown H, Ko N, Zagol-Ikapitte I, van der Hart M, Khroyan TV, Chuluun B, Priyam PG, Milne GL, Rassoulpour A, Boutaud O, Manning-Boğ AB, Heller HC, Andreasson KI. Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer’s disease model mice. Brain. 2016;139(Pt 7):2063-81. PMID: 27190010; PMCID: PMC4939702.

Wyss-Coray T. Ageing, neurodegeneration and brain rejuvenation. Nature. 2016;539(7628):180-186. PMID: 27830812; PMCID: PMC517260.

2015

Leaver K, Poston KL. Do CSF biomarkers predict progression to cognitive impairment in Parkinson‘s disease patients? a systematic review. Neuropsychology Review. 2015;25(4):411-23. PMID: 26626621; PMCID: PMC5152566.

Lehallier B, Essioux L, Gayan J, Alexandridis R, Nikolcheva T, Wyss-Coray T, Britschgi M. Combined plasma and cerebrospinal fluid signature for the prediction of midterm progression from mild cognitive impairment to Alzheimer disease. JAMA Neurology. 2015;1-10. PMID: 26659895; PMCID: PMC5214993.

Lehert P, Villaseca P, Hogervorst E, Maki PM, Henderson VW. Individually modifiable risk factors to ameliorate cognitive aging: a systematic review and meta-analysis. Climacteric. 2015;18(5):678-89. PMID: 26361790; PMCID: PMC5199766.

Müller-Oehring EM, Sullivan EV, Pfefferbaum A, Huang NC, Poston KL, Bronte-Stewart HM, Schulte T. Task-rest modulation of basal ganglia connectivity in mild to moderate Parkinson’s disease. Brain Imaging and Behavior. 2015;9(3):619-38. PMID: 25280970; PMCID: PMC4385510.